Sclerostin

mammalian protein found in Mus musculus
Protein protein Q14887297
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Sclerostin

Summary

Sclerostin is a protein[1].

Key Facts

  • Sclerostin's instance of is recorded as protein[2].
  • Sclerostin's subclass of is recorded as protein[3].
  • Sclerostin's UniProt protein ID is recorded as Q99P68[4].
  • Sclerostin's part of is recorded as Cystine-knot cytokine[5].
  • Sclerostin's part of is recorded as Sclerostin[6].
  • Sclerostin's RefSeq protein ID is recorded as NP_077769[7].
  • Sclerostin's RefSeq protein ID is recorded as XP_006534439[8].
  • Sclerostin's PDB structure ID is recorded as 2KD3[9].
  • Sclerostin's molecular function is recorded as transcription factor binding[10].
  • Sclerostin's molecular function is recorded as heparin binding[11].
  • Sclerostin's molecular function is recorded as protein binding[12].
  • Sclerostin's cell component is recorded as extracellular region[13].
  • Sclerostin's cell component is recorded as extracellular space[14].
  • Sclerostin's cell component is recorded as Golgi apparatus[15].
  • Sclerostin's cell component is recorded as protein-containing complex[16].
  • Sclerostin's biological process is recorded as negative regulation of protein-containing complex assembly[17].
  • Sclerostin's biological process is recorded as negative regulation of Wnt signaling pathway[18].
  • Sclerostin's biological process is recorded as positive regulation of transcription, DNA-templated[19].
  • Sclerostin's biological process is recorded as cellular response to parathyroid hormone stimulus[20].
  • Sclerostin's biological process is recorded as negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification[21].
  • Sclerostin's biological process is recorded as Wnt signaling pathway[22].
  • Sclerostin's biological process is recorded as negative regulation of canonical Wnt signaling pathway[23].
  • Sclerostin's biological process is recorded as ossification[24].
  • Sclerostin's biological process is recorded as negative regulation of ossification[25].
  • Sclerostin's biological process is recorded as negative regulation of BMP signaling pathway[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . Q905695. Retrieved . wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . Q20641742. Retrieved . wikidata.org.
  7. [8] . Q20641742. Retrieved . wikidata.org.
  8. [9] . Q905695. Retrieved . wikidata.org.
  9. [10] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Osteocyte control of bone formation via sclerostin, a novel BMP antagonist. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Conditionals by inversion provide a universal method for the generation of conditional alleles. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Osteocyte control of bone formation via sclerostin, a novel BMP antagonist. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Sclerostin. Retrieved May 3, 2026, from https://4ort.xyz/entity/sclerostin
MLA “Sclerostin.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/sclerostin.
BibTeX @misc{4ortxyz_sclerostin_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Sclerostin}}, year = {2026}, url = {https://4ort.xyz/entity/sclerostin}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Sclerostin — https://4ort.xyz/entity/sclerostin (retrieved 2026-05-03)

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