Protein kinase cAMP-dependent type II regulatory subunit alpha

mammalian protein found in Homo sapiens

Protein protein Q21105026

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Protein kinase cAMP-dependent type II regulatory subunit alpha

Summary

Protein kinase cAMP-dependent type II regulatory subunit alpha is a protein^[1].

Key Facts

Protein kinase cAMP-dependent type II regulatory subunit alpha's instance of is recorded as protein^[2].
Protein kinase cAMP-dependent type II regulatory subunit alpha's physically interacts with is recorded as Viroporin 3a^[3].
Protein kinase cAMP-dependent type II regulatory subunit alpha's UniProt protein ID is recorded as P13861^[4].
Protein kinase cAMP-dependent type II regulatory subunit alpha's part of is recorded as RmlC-like jelly roll fold^[5].
Protein kinase cAMP-dependent type II regulatory subunit alpha's part of is recorded as Cyclic nucleotide-binding-like^[6].
Protein kinase cAMP-dependent type II regulatory subunit alpha's part of is recorded as cAMP-dependent protein kinase regulatory subunit^[7].
Protein kinase cAMP-dependent type II regulatory subunit alpha's part of is recorded as cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, protein family^[8].
Protein kinase cAMP-dependent type II regulatory subunit alpha's part of is recorded as Cyclic nucleotide-binding domain, protein family^[9].
Protein kinase cAMP-dependent type II regulatory subunit alpha's part of is recorded as Cyclic nucleotide-binding, conserved site, protein family^[10].
Protein kinase cAMP-dependent type II regulatory subunit alpha's has part is recorded as Cyclic nucleotide-binding domain^[11].
Protein kinase cAMP-dependent type II regulatory subunit alpha's has part is recorded as Cyclic nucleotide-binding, conserved site^[12].
Protein kinase cAMP-dependent type II regulatory subunit alpha's has part is recorded as cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain^[13].
Protein kinase cAMP-dependent type II regulatory subunit alpha's RefSeq protein ID is recorded as NP_001308911^[14].
Protein kinase cAMP-dependent type II regulatory subunit alpha's RefSeq protein ID is recorded as NP_001308912^[15].
Protein kinase cAMP-dependent type II regulatory subunit alpha's RefSeq protein ID is recorded as NP_001308918^[16].
Protein kinase cAMP-dependent type II regulatory subunit alpha's RefSeq protein ID is recorded as NP_004148^[17].
Protein kinase cAMP-dependent type II regulatory subunit alpha's RefSeq protein ID is recorded as XP_005265372^[18].
Protein kinase cAMP-dependent type II regulatory subunit alpha's RefSeq protein ID is recorded as XP_011532244^[19].
Protein kinase cAMP-dependent type II regulatory subunit alpha's RefSeq protein ID is recorded as XP_011532245^[20].
Protein kinase cAMP-dependent type II regulatory subunit alpha's PDB structure ID is recorded as 2IZX^[21].
Protein kinase cAMP-dependent type II regulatory subunit alpha's PDB structure ID is recorded as 2KYG^[22].
Protein kinase cAMP-dependent type II regulatory subunit alpha's PDB structure ID is recorded as 4ZP3^[23].
Protein kinase cAMP-dependent type II regulatory subunit alpha's molecular function is recorded as nucleotide binding^[24].
Protein kinase cAMP-dependent type II regulatory subunit alpha's molecular function is recorded as protein kinase A catalytic subunit binding^[25].
Protein kinase cAMP-dependent type II regulatory subunit alpha's molecular function is recorded as cAMP binding^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Part of RmlC-like jelly roll fold, Cyclic nucleotide-binding-like, cAMP-dependent protein kinase regulatory subunit, cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, protein family, Cyclic nucleotide-binding domain, protein family, Cyclic nucleotide-binding, conserved site, protein family

Properties

Biological process regulation of protein phosphorylation, activation of protein kinase A activity, intracellular signal transduction, cellular response to glucagon stimulus, blood coagulation, negative regulation of cAMP-dependent protein kinase activity, renal water homeostasis, cGMP-mediated signaling

Cell component cytoplasm, cytosol, centrosome, membrane, focal adhesion, plasma membrane raft, plasma membrane, ciliary base, nucleotide-activated protein kinase complex, extracellular exosome, axoneme, cAMP-dependent protein kinase complex, cytosol, focal adhesion, membrane, protein-containing complex, extracellular exosome

Encoded by PRKAR2A

Found in taxon Homo sapiens

Has part(s) Cyclic nucleotide-binding domain, Cyclic nucleotide-binding, conserved site, cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain

Imported from wholeness_audit_2026-05-02

Molecular function nucleotide binding, protein kinase A catalytic subunit binding, cAMP binding, protein binding, cAMP-dependent protein kinase regulator activity, cAMP-dependent protein kinase inhibitor activity, ubiquitin protein ligase binding, protein domain specific binding, 3',5'-cyclic-GMP phosphodiesterase activity

Physically interacts with Viroporin 3a

External References (4)

Ensembl protein id ENSP00000265563, ENSP00000296446, ENSP00000394041, ENSP00000400840, ENSP00000409239, ENSP00000411432, ENSP00000416438

Pdb structure id 2IZX, 2KYG, 4ZP3

Refseq protein id NP_001308911, NP_001308912, NP_001308918, NP_004148, XP_005265372, XP_011532244, XP_011532245

Uniprot protein id P13861

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — physically interacts with (P129): Viroporin 3a. BioGRID. Retrieved 2020-04-19. thebiogrid.org. Provenance: wikidata.org.
[4] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — UniProt protein ID (P352): P13861. Q905695. Retrieved 2019-11-13. wikidata.org.
[5] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — part of (P361): RmlC-like jelly roll fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — part of (P361): Cyclic nucleotide-binding-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — part of (P361): cAMP-dependent protein kinase regulatory subunit. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — part of (P361): cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, protein family. wikidata.org.
[9] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — part of (P361): Cyclic nucleotide-binding domain, protein family. wikidata.org.
[10] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — part of (P361): Cyclic nucleotide-binding, conserved site, protein family. wikidata.org.
[11] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — has part(s) (P527): Cyclic nucleotide-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — has part(s) (P527): Cyclic nucleotide-binding, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — has part(s) (P527): cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — RefSeq protein ID (P637): NP_001308911. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — RefSeq protein ID (P637): NP_001308912. Q20641742. Retrieved 2020-05-30. wikidata.org.
[16] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — RefSeq protein ID (P637): NP_001308918. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — RefSeq protein ID (P637): NP_004148. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — RefSeq protein ID (P637): XP_005265372. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — RefSeq protein ID (P637): XP_011532244. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — RefSeq protein ID (P637): XP_011532245. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — PDB structure ID (P638): 2IZX. Q905695. Retrieved 2016-08-09. wikidata.org.
[22] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — PDB structure ID (P638): 2KYG. Q905695. Retrieved 2016-08-09. wikidata.org.
[23] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — PDB structure ID (P638): 4ZP3. Q905695. Retrieved 2016-08-09. wikidata.org.
[24] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — molecular function (P680): protein kinase A catalytic subunit binding. Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha — molecular function (P680): cAMP binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Protein kinase cAMP-dependent type II regulatory subunit alpha is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Protein kinase cAMP-dependent type II regulatory subunit alpha. Retrieved May 3, 2026, from https://4ort.xyz/entity/protein-kinase-camp-dependent-type-ii-regulatory-subunit-alpha-q21105026

MLA

“Protein kinase cAMP-dependent type II regulatory subunit alpha.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/protein-kinase-camp-dependent-type-ii-regulatory-subunit-alpha-q21105026.

BibTeX

@misc{4ortxyz_protein-kinase-camp-dependent-type-ii-regulatory-subunit-alpha-q21105026_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Protein kinase cAMP-dependent type II regulatory subunit alpha}}, year = {2026}, url = {https://4ort.xyz/entity/protein-kinase-camp-dependent-type-ii-regulatory-subunit-alpha-q21105026}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Protein kinase cAMP-dependent type II regulatory subunit alpha — https://4ort.xyz/entity/protein-kinase-camp-dependent-type-ii-regulatory-subunit-alpha-q21105026 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/protein-kinase-camp-dependent-type-ii-regulatory-subunit-alpha-q21105026 · Last refreshed: May 3, 2026