Protein kinase cAMP-dependent type I regulatory subunit alpha

mammalian protein found in Homo sapiens

Protein protein Q21105823

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Protein kinase cAMP-dependent type I regulatory subunit alpha

Summary

Protein kinase cAMP-dependent type I regulatory subunit alpha is a protein^[1].

Key Facts

Protein kinase cAMP-dependent type I regulatory subunit alpha's instance of is recorded as protein^[2].
Protein kinase cAMP-dependent type I regulatory subunit alpha's UniProt protein ID is recorded as P10644^[3].
Protein kinase cAMP-dependent type I regulatory subunit alpha's part of is recorded as RmlC-like jelly roll fold^[4].
Protein kinase cAMP-dependent type I regulatory subunit alpha's part of is recorded as Cyclic nucleotide-binding-like^[5].
Protein kinase cAMP-dependent type I regulatory subunit alpha's part of is recorded as cAMP-dependent protein kinase regulatory subunit^[6].
Protein kinase cAMP-dependent type I regulatory subunit alpha's part of is recorded as cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, protein family^[7].
Protein kinase cAMP-dependent type I regulatory subunit alpha's part of is recorded as Cyclic nucleotide-binding domain, protein family^[8].
Protein kinase cAMP-dependent type I regulatory subunit alpha's part of is recorded as Cyclic nucleotide-binding, conserved site, protein family^[9].
Protein kinase cAMP-dependent type I regulatory subunit alpha's has part is recorded as Cyclic nucleotide-binding domain^[10].
Protein kinase cAMP-dependent type I regulatory subunit alpha's has part is recorded as Cyclic nucleotide-binding, conserved site^[11].
Protein kinase cAMP-dependent type I regulatory subunit alpha's has part is recorded as cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain^[12].
Protein kinase cAMP-dependent type I regulatory subunit alpha's RefSeq protein ID is recorded as NP_001263218^[13].
Protein kinase cAMP-dependent type I regulatory subunit alpha's RefSeq protein ID is recorded as NP_001263219^[14].
Protein kinase cAMP-dependent type I regulatory subunit alpha's RefSeq protein ID is recorded as NP_001265362^[15].
Protein kinase cAMP-dependent type I regulatory subunit alpha's RefSeq protein ID is recorded as NP_002725^[16].
Protein kinase cAMP-dependent type I regulatory subunit alpha's RefSeq protein ID is recorded as NP_997636^[17].
Protein kinase cAMP-dependent type I regulatory subunit alpha's RefSeq protein ID is recorded as NP_997637^[18].
Protein kinase cAMP-dependent type I regulatory subunit alpha's RefSeq protein ID is recorded as XP_011523286^[19].
Protein kinase cAMP-dependent type I regulatory subunit alpha's RefSeq protein ID is recorded as NP_001356318^[20].
Protein kinase cAMP-dependent type I regulatory subunit alpha's RefSeq protein ID is recorded as NP_001356319^[21].
Protein kinase cAMP-dependent type I regulatory subunit alpha's molecular function is recorded as nucleotide binding^[22].
Protein kinase cAMP-dependent type I regulatory subunit alpha's molecular function is recorded as protein kinase A catalytic subunit binding^[23].
Protein kinase cAMP-dependent type I regulatory subunit alpha's molecular function is recorded as cAMP binding^[24].
Protein kinase cAMP-dependent type I regulatory subunit alpha's molecular function is recorded as protein binding^[25].
Protein kinase cAMP-dependent type I regulatory subunit alpha's molecular function is recorded as cAMP-dependent protein kinase regulator activity^[26].

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Quick Facts

Instance of protein

Part of RmlC-like jelly roll fold, Cyclic nucleotide-binding-like, cAMP-dependent protein kinase regulatory subunit, cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, protein family, Cyclic nucleotide-binding domain, protein family, Cyclic nucleotide-binding, conserved site, protein family

Properties

Biological process regulation of protein phosphorylation, activation of protein kinase A activity, intracellular signal transduction, negative regulation of protein kinase activity, regulation of transcription by RNA polymerase II, cellular response to glucagon stimulus, mesoderm formation, blood coagulation, female meiotic nuclear division, negative regulation of meiotic nuclear division, cardiac muscle cell proliferation, negative regulation of cAMP-dependent protein kinase activity, negative regulation of activated T cell proliferation, development of the heart, renal water homeostasis, regulation of protein kinase activity, sarcomere organization, cGMP-mediated signaling

Cell component cytoplasm, cytosol, membrane, plasma membrane raft, neuromuscular junction, plasma membrane, ciliary base, nucleotide-activated protein kinase complex, immunological synapse, cAMP-dependent protein kinase complex, axoneme, cytosol, membrane, protein-containing complex, synapse, glutamatergic synapse

Encoded by PRKAR1A

Found in taxon Homo sapiens

Has part(s) Cyclic nucleotide-binding domain, Cyclic nucleotide-binding, conserved site, cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain

Imported from wholeness_audit_2026-05-02

Length unit: www.wikidata.org, amount: +381

Mass unit: www.wikidata.org, amount: +42.982

Molecular function nucleotide binding, protein kinase A catalytic subunit binding, cAMP binding, protein binding, cAMP-dependent protein kinase regulator activity, cAMP-dependent protein kinase inhibitor activity, ubiquitin protein ligase binding, protein domain specific binding, 3',5'-cyclic-GMP phosphodiesterase activity

External References (3)

Ensembl protein id ENSP00000351410, ENSP00000376475, ENSP00000445625, ENSP00000464977, ENSP00000466459, ENSP00000468106, ENSP00000376474, ENSP00000464701, ENSP00000464715, ENSP00000465013, ENSP00000465445, ENSP00000465740, ENSP00000466314, ENSP00000466649, ENSP00000466722, ENSP00000467311, ENSP00000467500, ENSP00000467867

Refseq protein id NP_001263218, NP_001263219, NP_001265362, NP_002725, NP_997636, NP_997637, XP_011523286, NP_001356318, NP_001356319

Uniprot protein id P10644

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — UniProt protein ID (P352): P10644. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — part of (P361): RmlC-like jelly roll fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — part of (P361): Cyclic nucleotide-binding-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — part of (P361): cAMP-dependent protein kinase regulatory subunit. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — part of (P361): cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, protein family. wikidata.org.
[8] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — part of (P361): Cyclic nucleotide-binding domain, protein family. wikidata.org.
[9] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — part of (P361): Cyclic nucleotide-binding, conserved site, protein family. wikidata.org.
[10] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — has part(s) (P527): Cyclic nucleotide-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — has part(s) (P527): Cyclic nucleotide-binding, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — has part(s) (P527): cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — RefSeq protein ID (P637): NP_001263218. Q20641742. Retrieved 2020-05-30. wikidata.org.
[14] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — RefSeq protein ID (P637): NP_001263219. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — RefSeq protein ID (P637): NP_001265362. Q20641742. Retrieved 2020-05-30. wikidata.org.
[16] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — RefSeq protein ID (P637): NP_002725. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — RefSeq protein ID (P637): NP_997636. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — RefSeq protein ID (P637): NP_997637. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — RefSeq protein ID (P637): XP_011523286. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — RefSeq protein ID (P637): NP_001356318. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — RefSeq protein ID (P637): NP_001356319. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — molecular function (P680): protein kinase A catalytic subunit binding. Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — molecular function (P680): cAMP binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — molecular function (P680): protein binding. Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha — molecular function (P680): cAMP-dependent protein kinase regulator activity. Molecular cloning, cDNA structure and deduced amino acid sequence for a type I regulatory subunit of cAMP-dependent protein kinase from human testis. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Protein kinase cAMP-dependent type I regulatory subunit alpha is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Protein kinase cAMP-dependent type I regulatory subunit alpha. Retrieved May 3, 2026, from https://4ort.xyz/entity/protein-kinase-camp-dependent-type-i-regulatory-subunit-alpha-q21105823

MLA

“Protein kinase cAMP-dependent type I regulatory subunit alpha.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/protein-kinase-camp-dependent-type-i-regulatory-subunit-alpha-q21105823.

BibTeX

@misc{4ortxyz_protein-kinase-camp-dependent-type-i-regulatory-subunit-alpha-q21105823_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Protein kinase cAMP-dependent type I regulatory subunit alpha}}, year = {2026}, url = {https://4ort.xyz/entity/protein-kinase-camp-dependent-type-i-regulatory-subunit-alpha-q21105823}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Protein kinase cAMP-dependent type I regulatory subunit alpha — https://4ort.xyz/entity/protein-kinase-camp-dependent-type-i-regulatory-subunit-alpha-q21105823 (retrieved 2026-05-03)

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