Polo like kinase 1

mammalian protein found in Mus musculus

Protein protein Q21988920

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Polo like kinase 1

Summary

Polo like kinase 1 is a protein^[1].

Key Facts

Polo like kinase 1's instance of is recorded as protein^[2].
Polo like kinase 1's subclass of is recorded as protein^[3].
Polo like kinase 1's UniProt protein ID is recorded as Q07832^[4].
Polo like kinase 1's part of is recorded as Protein kinase-like domain superfamily^[5].
Polo like kinase 1's part of is recorded as POLO box domain superfamily^[6].
Polo like kinase 1's part of is recorded as First polo-box domain, protein family^[7].
Polo like kinase 1's part of is recorded as polo-like kinase 1, catalytic domain, protein family^[8].
Polo like kinase 1's part of is recorded as POLO box domain, protein family^[9].
Polo like kinase 1's part of is recorded as Protein kinase domain, protein family^[10].
Polo like kinase 1's part of is recorded as Second polo-box domain, protein family^[11].
Polo like kinase 1's part of is recorded as Protein kinase, ATP binding site, protein family^[12].
Polo like kinase 1's part of is recorded as Serine/threonine-protein kinase, active site, protein family^[13].
Polo like kinase 1's has part is recorded as Second polo-box domain^[14].
Polo like kinase 1's has part is recorded as POLO box domain^[15].
Polo like kinase 1's has part is recorded as serine/threonine-protein kinase, active site^[16].
Polo like kinase 1's has part is recorded as Polo-like kinase 1, catalytic domain^[17].
Polo like kinase 1's has part is recorded as protein kinase, ATP binding site^[18].
Polo like kinase 1's has part is recorded as protein kinase domain^[19].
Polo like kinase 1's has part is recorded as First polo-box domain^[20].
Polo like kinase 1's RefSeq protein ID is recorded as NP_035251^[21].
Polo like kinase 1's PDB structure ID is recorded as 5DMV^[22].
Polo like kinase 1's PDB structure ID is recorded as 5DMS^[23].
Polo like kinase 1's PDB structure ID is recorded as 5DNJ^[24].
Polo like kinase 1's molecular function is recorded as transferase activity^[25].
Polo like kinase 1's molecular function is recorded as nucleotide binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Protein kinase-like domain superfamily, POLO box domain superfamily, First polo-box domain, protein family, polo-like kinase 1, catalytic domain, protein family, POLO box domain, protein family, Protein kinase domain, protein family, Second polo-box domain, protein family, Protein kinase, ATP binding site, protein family, Serine/threonine-protein kinase, active site, protein family

Properties

Biological process phosphorylation, negative regulation of cyclin-dependent protein serine/threonine kinase activity, establishment of protein localization, synaptonemal complex disassembly, mitotic cytokinesis, negative regulation of apoptotic process, negative regulation of transcription by RNA polymerase II, homologous chromosome segregation, regulation of mitotic spindle assembly, mitotic spindle assembly checkpoint signaling, cell division, protein phosphorylation, G2/M transition of mitotic cell cycle, positive regulation of peptidyl-threonine phosphorylation, peptidyl-serine phosphorylation, microtubule bundle formation, protein ubiquitination, protein destabilization, regulation of mitotic cell cycle, positive regulation of ubiquitin-protein transferase activity, positive regulation of proteolysis, mitotic sister chromatid segregation, regulation of mitotic metaphase/anaphase transition, cell cycle, regulation of protein binding, protein localization to chromatin, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, female meiosis chromosome segregation, positive regulation of ubiquitin protein ligase activity, nuclear membrane disassembly, protein localization to nuclear envelope, mitotic cell cycle, centrosome cycle, regulation of cytokinesis, mitotic G2 DNA damage checkpoint signaling, polar body extrusion after meiotic divisions, peptidyl-serine phosphorylation, protein localization to organelle, regulation of protein binding, mitotic cell cycle, regulation of cytokinesis, establishment of mitotic spindle orientation, regulation of protein localization to cell cortex, establishment of mitotic spindle orientation, regulation of protein localization to cell cortex

Cell component centrosome, spindle pole, microtubule cytoskeleton, spindle, chromosome, microtubule organizing center, midbody, spindle microtubule, spindle midzone, chromatin, synaptonemal complex, chromosome, centromeric region, cytoskeleton, nucleus, kinetochore, cytoplasm, centriole, centriolar satellite, spindle pole, nucleus, cytoplasm, centrosome

Encoded by Plk1

Found in taxon house mouse

Has part(s) Second polo-box domain, POLO box domain, serine/threonine-protein kinase, active site, Polo-like kinase 1, catalytic domain, protein kinase, ATP binding site, protein kinase domain, First polo-box domain

Imported from wholeness_audit_2026-05-02

Molecular function transferase activity, nucleotide binding, protein kinase activity, microtubule binding, kinase activity, protein serine/threonine kinase activity, protein binding, anaphase-promoting complex binding, protein kinase binding, magnesium ion binding, ATP binding, identical protein binding, protein serine/threonine kinase activity, protein serine/threonine kinase activity

External References (4)

Ensembl protein id ENSMUSP00000033154, ENSMUSP00000146253, ENSMUSP00000145631

Pdb structure id 5DMV, 5DMS, 5DNJ

Refseq protein id NP_035251

Uniprot protein id Q07832

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Polo like kinase 1 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Polo like kinase 1 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Polo like kinase 1 — UniProt protein ID (P352): Q07832. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Polo like kinase 1 — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Polo like kinase 1 — part of (P361): POLO box domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Polo like kinase 1 — part of (P361): First polo-box domain, protein family. wikidata.org.
[8] ↑ Polo like kinase 1 — part of (P361): polo-like kinase 1, catalytic domain, protein family. wikidata.org.
[9] ↑ Polo like kinase 1 — part of (P361): POLO box domain, protein family. wikidata.org.
[10] ↑ Polo like kinase 1 — part of (P361): Protein kinase domain, protein family. wikidata.org.
[11] ↑ Polo like kinase 1 — part of (P361): Second polo-box domain, protein family. wikidata.org.
[12] ↑ Polo like kinase 1 — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[13] ↑ Polo like kinase 1 — part of (P361): Serine/threonine-protein kinase, active site, protein family. wikidata.org.
[14] ↑ Polo like kinase 1 — has part(s) (P527): Second polo-box domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Polo like kinase 1 — has part(s) (P527): POLO box domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Polo like kinase 1 — has part(s) (P527): serine/threonine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Polo like kinase 1 — has part(s) (P527): Polo-like kinase 1, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Polo like kinase 1 — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Polo like kinase 1 — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Polo like kinase 1 — has part(s) (P527): First polo-box domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Polo like kinase 1 — RefSeq protein ID (P637): NP_035251. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Polo like kinase 1 — PDB structure ID (P638): 5DMV. Q905695. Retrieved 2016-08-10. wikidata.org.
[23] ↑ Polo like kinase 1 — PDB structure ID (P638): 5DMS. Q905695. Retrieved 2016-08-10. wikidata.org.
[24] ↑ Polo like kinase 1 — PDB structure ID (P638): 5DNJ. Q905695. Retrieved 2016-08-10. wikidata.org.
[25] ↑ Polo like kinase 1 — molecular function (P680): transferase activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Polo like kinase 1 — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Polo like kinase 1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Polo like kinase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/polo-like-kinase-1-q21988920

MLA

“Polo like kinase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/polo-like-kinase-1-q21988920.

BibTeX

@misc{4ortxyz_polo-like-kinase-1-q21988920_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Polo like kinase 1}}, year = {2026}, url = {https://4ort.xyz/entity/polo-like-kinase-1-q21988920}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Polo like kinase 1 — https://4ort.xyz/entity/polo-like-kinase-1-q21988920 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/polo-like-kinase-1-q21988920 · Last refreshed: May 3, 2026