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parthenolide

chemical compound
Class type of: germacrane sesquiterpenoid Q2662393

Facts

9 properties
Instance of
type of chemical entity
Subclass of
germacrane sesquiterpenoid
Canonical SMILES
CC1=CCCC2(C(O2)C3C(CC1)C(=C)C(=O)O3)C[3]
Chemical formula
C₁₅H₂₀O₃[4]
Found in taxon
Tanacetum parthenium, Tanacetum vulgare, Tanacetum niveum, Anthemis cretica, Anthemis macedonica, Anthemis melampodina, Eriocephalus kingesii, Magnolia virginiana, Staehelina fruticosa, Carpesium longifolium, Cyathocline purpurea, Pentanema aschersonianum, Magnolia denudata, Magnolia grandiflora, Magnolia, Magnolia salicifolia, Magnolia champaca, Magnolia nilagirica, Tanacetum argenteum, Tanacetum densum, Tanacetum larvatum, Tarchonanthus camphoratus, Magnolia rajaniana, Magnolia baillonii, Magnolia ovata, Magnolia odora, Ambrosia dumosa, Hirtellina fruticosa, Asteraceae[5][6][7][8][9][10][11][12][13][14][15][16][17][18]
Isomeric SMILES
C=C1C(=O)O[C@H]2[C@H]1CC/C(C)=C\CC[C@@]1(C)O[C@@H]21[19]
Mass
+248.141245[20]
Stereoisomer of
(1S,2S,4S,7Z,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one, LSM-4225, (1R,2S,4S,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one, (1R,2R,4S,7E,11R)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one, (1aR,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, (1S,2R,4S,7E,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one, LSM-4576, (1aS,4E,7aS,10aR,10bS)-1a,5-Dimethyl-8-methylene-1a,2,3,6,7,7aalpha,10aalpha,10bbeta-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(8H)-one, LSM-5227, (-)-parthenolide, (1S,2R,4R,7E,11R)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one, (1S,2S,4S,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one, 7-Epi-parthenolide[22][23][24][25][26][27][28][29][30][31][32][33][34]
Subject has role
non-steroidal anti-inflammatory drug[21]
🏷️ Also known as
en parthenolide fa پارتنولید fr C15H20O3 fr Parthénolide it Partenolide ja パルテノリド pt Partenolídeo ru Партенолид zh 银胶菊内酯
🔖 Identifiers · 29
OpenAlex ID
C2780321935
CAB ID
237015
CAS Registry Number
20554-84-1
ChEMBL ID
CHEMBL3186408
ChemSpider ID
4510242
CosIng number
97313
DSSTOX compound identifier
DTXCID0020579
DSSTox substance ID
DTXSID2040579
DrugBank ID
DB13063
EC number
692-532-0
ECHA Substance Infocard ID
100.220.558
Freebase ID
/m/0c7_p3
Show all 29 identifiers +17
IEDB Epitope ID
115014
InChI
InChI=1S/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5-/t11-,12-,13-,15+/m0/s1
InChIKey
KTEXNACQROZXEV-QLIGOWBFSA-N, KTEXNACQROZXEV-PVLRGYAZSA-N
KEGG ID
C07609
KNApSAcK ID
C00003345
MeSH descriptor ID
C002669
Microsoft Academic ID (discontinued)
2780321935
Nikkaji ID
J15.880A
Probes And Drugs ID
PD010752
PubChem CID
5420805
RTECS number
LY4220000
Reaxys registry number
3550011
RxNorm CUI
32941
SureChEMBL ID
8219
UMLS CUI
C0894280
UNII
2RDB26I5ZB
UniChem compound ID
16106178

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🔗 Connections
Found in taxon 23
Asteraceae, Magnolia, Tanacetum vulgare, Magnolia grandiflora, Magnolia champaca, Tanacetum parthenium, Magnolia denudata, Magnolia virginiana +15 more
Subject has role 1
non-steroidal anti-inflammatory drug
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Summary

parthenolide is a type of chemical entity[1]. parthenolide is a type of germacrane sesquiterpenoid[2].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . PubChem. Retrieved . wikidata.org.
  2. [4] ↑ . PubChem. Retrieved . wikidata.org.
  3. [2] ↑ . wikidata.org.
  4. [5] ↑ . Comparison of Extraction Procedures for Parthenolide inTanacetum parthenium. wikidata.org.
  5. [6] ↑ . Effects of extracts ofTanacetum species on human polymorphonuclear leucocyte activityin vitro. wikidata.org.
  6. [7] ↑ . Effects of extracts ofTanacetum species on human polymorphonuclear leucocyte activityin vitro. wikidata.org.
  7. [8] ↑ . Sesquiterpene lactones as chemotaxonomic markers in genus Anthemis. wikidata.org.
  8. [9] ↑ . Sesquiterpene lactones as chemotaxonomic markers in genus Anthemis. wikidata.org.
  9. [10] ↑ . Sesquiterpene lactones as chemotaxonomic markers in genus Anthemis. wikidata.org.
  10. [11] ↑ . Sesquiterpene lactones and other constituents from Eriocephalus species. wikidata.org.
  11. [12] ↑ . Sesquiterpenes from southern Magnolia virginiana. wikidata.org.
  12. [13] ↑ . Sesquiterpene lactones from Staehelina fruticosa.. wikidata.org.
  13. [14] ↑ . Xanthanolides, germacranolides, and other constituents from Carpesium longifolium. wikidata.org.
  14. [15] ↑ . A germacranolide from Cyathocline lutea. wikidata.org.
  15. [16] ↑ . Sesquiterpenic lactones of Inula aschersoniana JANKA var. aschersoniana species. wikidata.org.
  16. [17] ↑ . Cytocidal Principles of Magnolia Denudata. wikidata.org.
  17. [18] ↑ . A guaianolide from Magnolia grandiflora. wikidata.org.
  18. [19] ↑ . wikidata.org.
  19. [20] ↑ . PubChem. Retrieved . wikidata.org.
  20. [21] ↑ . Medical Subject Headings. Retrieved . wikidata.org.
  21. [22] ↑ . wikidata.org.
  22. [23] ↑ . wikidata.org.
  23. [24] ↑ . wikidata.org.
  24. [25] ↑ . wikidata.org.
  25. [26] ↑ . wikidata.org.
  26. [27] ↑ . wikidata.org.
  27. [28] ↑ . wikidata.org.
  28. [29] ↑ . wikidata.org.
  29. [30] ↑ . wikidata.org.
  30. [31] ↑ . wikidata.org.
  31. [32] ↑ . wikidata.org.
  32. [33] ↑ . wikidata.org.
  33. [34] ↑ . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). parthenolide. Retrieved November 8, 2026, from https://4ort.xyz/entity/parthenolide
MLA “parthenolide.” 4ort.xyz Knowledge Graph, 4ort.xyz, 8 Nov. 2026, https://4ort.xyz/entity/parthenolide.
BibTeX @misc{4ortxyz_parthenolide_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{parthenolide}}, year = {2026}, url = {https://4ort.xyz/entity/parthenolide}, note = {Accessed: 2026-11-08}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): parthenolide — https://4ort.xyz/entity/parthenolide (retrieved 2026-11-08)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 20w ago · Nabbegat · 2026-06-19 view diff on Wikidata ↗
    Stereoisomer of → (1S,2S,4S,7Z,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatric, LSM-4225, (1R,2S,4S,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricycl +1
    Instance of → type of chemical entity
    InChIKey → KTEXNACQROZXEV-QLIGOWBFSA-N, KTEXNACQROZXEV-PVLRGYAZSA-N
    Found in taxon → Tanacetum parthenium, Tanacetum vulgare, Tanacetum niveum +1
    + 3 other properties edited (see Wikidata diff for full list)
    "Changed [tr] labels, descriptions or aliases: QuickStatements 3.0 batch #37300"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.