Parkinson disease (autosomal recessive, early onset) 7

mammalian protein found in Mus musculus

Protein protein Q21989850

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Parkinson disease (autosomal recessive, early onset) 7

Summary

Parkinson disease (autosomal recessive, early onset) 7 is a protein^[1].

Key Facts

Parkinson disease (autosomal recessive, early onset) 7's instance of is recorded as protein^[2].
Parkinson disease (autosomal recessive, early onset) 7's UniProt protein ID is recorded as Q99LX0^[3].
Parkinson disease (autosomal recessive, early onset) 7's part of is recorded as Protein/nucleic acid deglycase DJ-1^[4].
Parkinson disease (autosomal recessive, early onset) 7's part of is recorded as Class I glutamine amidotransferase-like^[5].
Parkinson disease (autosomal recessive, early onset) 7's part of is recorded as membrane protein^[6].
Parkinson disease (autosomal recessive, early onset) 7's part of is recorded as DJ-1/PfpI domain, protein family^[7].
Parkinson disease (autosomal recessive, early onset) 7's has part is recorded as DJ-1/PfpI^[8].
Parkinson disease (autosomal recessive, early onset) 7's RefSeq protein ID is recorded as NP_065594^[9].
Parkinson disease (autosomal recessive, early onset) 7's RefSeq protein ID is recorded as XP_036020176^[10].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as signaling receptor binding^[11].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as cytokine binding^[12].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as cupric ion binding^[13].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as transcription factor binding^[14].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as L-dopa decarboxylase activator activity^[15].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as peptidase activity^[16].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as kinase binding^[17].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as tyrosine 3-monooxygenase activator activity^[18].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as enzyme binding^[19].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as mRNA binding^[20].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as protein homodimerization activity^[21].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as scaffold protein binding^[22].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as small protein activating enzyme binding^[23].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as ubiquitin-like protein conjugating enzyme binding^[24].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as protein binding^[25].
Parkinson disease (autosomal recessive, early onset) 7's molecular function is recorded as peroxiredoxin activity^[26].

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Quick Facts

Instance of protein

Part of Protein/nucleic acid deglycase DJ-1, Class I glutamine amidotransferase-like, membrane protein, DJ-1/PfpI domain, protein family

Properties

Biological process negative regulation of neuron apoptotic process, positive regulation of transcription regulatory region DNA binding, negative regulation of protein sumoylation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, negative regulation of protein binding, synaptic transmission, dopaminergic, positive regulation of interleukin-8 production, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, cell population proliferation, cellular response to glyoxal, negative regulation of protein acetylation, positive regulation of reactive oxygen species biosynthetic process, positive regulation of oxidative phosphorylation uncoupler activity, negative regulation of protein catabolic process, adult locomotory behavior, regulation of neuron apoptotic process, negative regulation of extrinsic apoptotic signaling pathway, negative regulation of cell death, glycolate biosynthetic process, positive regulation of protein homodimerization activity, negative regulation of gene expression, single fertilization, positive regulation of peptidyl-serine phosphorylation, positive regulation of mitochondrial electron transport, NADH to ubiquinone, negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway, negative regulation of oxidative stress-induced cell death, inflammatory response, negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway, negative regulation of neuron death, negative regulation of protein phosphorylation, negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, negative regulation of protein kinase activity, negative regulation of oxidative stress-induced neuron death, protein stabilization, membrane depolarization, mitochondrion organization, positive regulation of DNA-binding transcription factor activity, negative regulation of apoptotic process, proteolysis, negative regulation of protein K48-linked deubiquitination, dopamine uptake involved in synaptic transmission, positive regulation of tyrosine 3-monooxygenase activity, positive regulation of L-dopa decarboxylase activity, negative regulation of hydrogen peroxide-induced neuron death, regulation of inflammatory response, regulation of androgen receptor signaling pathway, negative regulation of hydrogen peroxide-induced cell death, response to hydrogen peroxide, detoxification of copper ion, positive regulation of superoxide dismutase activity, positive regulation of protein localization to nucleus, positive regulation of dopamine biosynthetic process, positive regulation of L-dopa biosynthetic process, membrane hyperpolarization, detoxification of mercury ion, negative regulation of TRAIL-activated apoptotic signaling pathway, negative regulation of ubiquitin-specific protease activity, autophagy, cellular response to reactive oxygen species, regulation of mitochondrial membrane potential, negative regulation of protein ubiquitination, hydrogen peroxide metabolic process, positive regulation of gene expression, negative regulation of protein export from nucleus, negative regulation of ubiquitin-protein transferase activity, positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway, cellular response to oxidative stress, positive regulation of androgen receptor activity, positive regulation of pyrroline-5-carboxylate reductase activity, positive regulation of transcription by RNA polymerase II, cellular response to hydrogen peroxide, cellular oxidant detoxification, positive regulation of acute inflammatory response to antigenic stimulus, lactate biosynthetic process, positive regulation of NAD(P)H oxidase activity, peptidyl-cysteine deglycation, peptidyl-arginine deglycation, peptidyl-lysine deglycation, protein deglycation, glyoxal removal, glutathione deglycation, glyoxal metabolic process, negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway, protein deglycosylation, methylglyoxal metabolic process, protein deglycation, methylglyoxal removal, cellular response to DNA damage stimulus, insulin secretion, glucose homeostasis, negative regulation of reactive oxygen species biosynthetic process, DNA repair, guanine deglycation, guanine deglycation, methylglyoxal removal, guanine deglycation, glyoxal removal, response to oxidative stress, protein deglycation, glyoxal removal, guanine deglycation, glyoxal removal, negative regulation of NMDA glutamate receptor activity, positive regulation of fertilization

Cell component cytoplasm, cytosol, membrane, mitochondrial intermembrane space, mitochondrion, neuron projection, nucleus, mitochondrial respiratory chain complex I, endoplasmic reticulum, membrane raft, chromatin, plasma membrane, mitochondrial matrix, cell body, PML body, presynapse, perinuclear region of cytoplasm, nucleus, mitochondrion, cytosol, axon, membrane raft, sperm head, mitochondrial respiratory chain complex I

Encoded by Park7

Found in taxon house mouse

Has part(s) DJ-1/PfpI

Imported from wholeness_audit_2026-05-02

Molecular function signaling receptor binding, cytokine binding, cupric ion binding, transcription factor binding, L-dopa decarboxylase activator activity, peptidase activity, kinase binding, tyrosine 3-monooxygenase activator activity, enzyme binding, mRNA binding, protein homodimerization activity, scaffold protein binding, small protein activating enzyme binding, ubiquitin-like protein conjugating enzyme binding, protein binding, peroxiredoxin activity, copper ion binding, mercury ion binding, oxidoreductase activity, acting on peroxide as acceptor, androgen receptor binding, superoxide dismutase copper chaperone activity, RNA binding, identical protein binding, ubiquitin-specific protease binding, hydrolase activity, cuprous ion binding, transcription coactivator activity, protein deglycase activity, cadherin binding, protein deglycase activity, protein-containing complex binding

External References (3)

Ensembl protein id ENSMUSP00000030805, ENSMUSP00000101298, ENSMUSP00000101299, ENSMUSP00000101300, ENSMUSP00000101301, ENSMUSP00000115875, ENSMUSP00000120832, ENSMUSP00000122265

Refseq protein id NP_065594, XP_036020176

Uniprot protein id Q99LX0

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Parkinson disease (autosomal recessive, early onset) 7 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Parkinson disease (autosomal recessive, early onset) 7 — UniProt protein ID (P352): Q99LX0. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ Parkinson disease (autosomal recessive, early onset) 7 — part of (P361): Protein/nucleic acid deglycase DJ-1. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Parkinson disease (autosomal recessive, early onset) 7 — part of (P361): Class I glutamine amidotransferase-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Parkinson disease (autosomal recessive, early onset) 7 — part of (P361): membrane protein. wikidata.org.
[7] ↑ Parkinson disease (autosomal recessive, early onset) 7 — part of (P361): DJ-1/PfpI domain, protein family. wikidata.org.
[8] ↑ Parkinson disease (autosomal recessive, early onset) 7 — has part(s) (P527): DJ-1/PfpI. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Parkinson disease (autosomal recessive, early onset) 7 — RefSeq protein ID (P637): NP_065594. Q20641742. Retrieved 2022-03-20. wikidata.org.
[10] ↑ Parkinson disease (autosomal recessive, early onset) 7 — RefSeq protein ID (P637): XP_036020176. Q20641742. Retrieved 2022-03-20. wikidata.org.
[11] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): signaling receptor binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): cytokine binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): cupric ion binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): transcription factor binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): L-dopa decarboxylase activator activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): peptidase activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): kinase binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): tyrosine 3-monooxygenase activator activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): enzyme binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): mRNA binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): protein homodimerization activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): scaffold protein binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): small protein activating enzyme binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): ubiquitin-like protein conjugating enzyme binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): protein binding. Park7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsis. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Parkinson disease (autosomal recessive, early onset) 7 — molecular function (P680): peroxiredoxin activity. DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Parkinson disease (autosomal recessive, early onset) 7 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Parkinson disease (autosomal recessive, early onset) 7. Retrieved May 3, 2026, from https://4ort.xyz/entity/parkinson-disease-autosomal-recessive-early-onset-7

MLA

“Parkinson disease (autosomal recessive, early onset) 7.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/parkinson-disease-autosomal-recessive-early-onset-7.

BibTeX

@misc{4ortxyz_parkinson-disease-autosomal-recessive-early-onset-7_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Parkinson disease (autosomal recessive, early onset) 7}}, year = {2026}, url = {https://4ort.xyz/entity/parkinson-disease-autosomal-recessive-early-onset-7}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Parkinson disease (autosomal recessive, early onset) 7 — https://4ort.xyz/entity/parkinson-disease-autosomal-recessive-early-onset-7 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/parkinson-disease-autosomal-recessive-early-onset-7 · Last refreshed: May 3, 2026