obesity due to prohormone convertase 1 deficiency

Prohormone convertase-I deficiency is the rarest form of monogenic obesity. The disorder is characterised by severe childhood obesity, hypoadrenalism, reactive hypoglycaemia, and elevated circulating levels of certain prohormones.
MedicalCondition rare_disease Q55782886
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obesity due to prohormone convertase 1 deficiency

Summary

obesity due to prohormone convertase 1 deficiency is a rare disease[1].

Key Facts

  • obesity due to prohormone convertase 1 deficiency's instance of is recorded as rare disease[2].
  • obesity due to prohormone convertase 1 deficiency's instance of is recorded as class of disease[3].
  • obesity due to prohormone convertase 1 deficiency's subclass of is recorded as hypogonadotropic hypogonadism associated with other endocrinopathies[4].
  • obesity due to prohormone convertase 1 deficiency's subclass of is recorded as obesity due to congenital leptin resistance[5].
  • obesity due to prohormone convertase 1 deficiency's subclass of is recorded as syndrome[6].
  • obesity due to prohormone convertase 1 deficiency's subclass of is recorded as autosomal recessive disease[7].
  • obesity due to prohormone convertase 1 deficiency's MeSH descriptor ID is recorded as C563423[8].
  • obesity due to prohormone convertase 1 deficiency's OMIM ID is recorded as 600955[9].
  • obesity due to prohormone convertase 1 deficiency's KEGG ID is recorded as H02105[10].
  • obesity due to prohormone convertase 1 deficiency's Disease Ontology ID is recorded as DOID:0111698[11].
  • obesity due to prohormone convertase 1 deficiency's Orphanet ID is recorded as 71528[12].
  • obesity due to prohormone convertase 1 deficiency's genetic association is recorded as PCSK1[13].
  • obesity due to prohormone convertase 1 deficiency's exact match is recorded as http://www.orpha.net/ORDO/Orphanet_71528[14].
  • obesity due to prohormone convertase 1 deficiency's exact match is recorded as http://purl.obolibrary.org/obo/DOID_0111698[15].
  • obesity due to prohormone convertase 1 deficiency's exact match is recorded as http://identifiers.org/doid/DOID:0111698[16].
  • obesity due to prohormone convertase 1 deficiency's UMLS CUI is recorded as C1833053[17].
  • obesity due to prohormone convertase 1 deficiency's UMLS CUI is recorded as C4302878[18].
  • obesity due to prohormone convertase 1 deficiency's ICD-10-CM is recorded as E66.8[19].
  • obesity due to prohormone convertase 1 deficiency's Mondo ID is recorded as MONDO_0010961[20].
  • obesity due to prohormone convertase 1 deficiency's ICD-11 ID is recorded as 331161581[21].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . wikidata.org.
  2. [3] . wikidata.org.
  3. [4] . Monarch Disease Ontology release 2018-06-29. Retrieved . wikidata.org.
  4. [5] . Monarch Disease Ontology release 2018-06-29. Retrieved . wikidata.org.
  5. [6] . Disease Ontology. Retrieved . wikidata.org.
  6. [7] . Disease Ontology. Retrieved . wikidata.org.
  7. [8] . Monarch Disease Ontology release 2018-06-29. Retrieved . wikidata.org.
  8. [9] . Monarch Disease Ontology release 2018-06-29. Retrieved . wikidata.org.
  9. [10] . wikidata.org.
  10. [11] . Disease Ontology. Retrieved . wikidata.org.
  11. [12] . Monarch Disease Ontology release 2018-06-29. Retrieved . wikidata.org.
  12. [13] . Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  13. [14] . wikidata.org.
  14. [15] . Disease Ontology. Retrieved . wikidata.org.
  15. [16] . Identifiers.org. registry.identifiers.org. Provenance: wikidata.org.
  16. [17] . Monarch Disease Ontology release 2018-06-29. Retrieved . wikidata.org.
  17. [18] . UMLS 2023. Retrieved . wikidata.org.
  18. [19] . Monarch Disease Ontology release 2018-06-29. Retrieved . wikidata.org.
  19. [20] . wikidata.org.
  20. [21] . wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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APA 4ort.xyz Knowledge Graph. (2026). obesity due to prohormone convertase 1 deficiency. Retrieved May 3, 2026, from https://4ort.xyz/entity/obesity-due-to-prohormone-convertase-1-deficiency
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BibTeX @misc{4ortxyz_obesity-due-to-prohormone-convertase-1-deficiency_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{obesity due to prohormone convertase 1 deficiency}}, year = {2026}, url = {https://4ort.xyz/entity/obesity-due-to-prohormone-convertase-1-deficiency}, note = {Accessed: 2026-05-03}}
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