Nuclear receptor subfamily 1, group H, member 3

mammalian protein found in Mus musculus

Protein protein Q21989817

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Nuclear receptor subfamily 1, group H, member 3

Summary

Nuclear receptor subfamily 1, group H, member 3 is a protein^[1].

Key Facts

Nuclear receptor subfamily 1, group H, member 3's instance of is recorded as protein^[2].
Nuclear receptor subfamily 1, group H, member 3's subclass of is recorded as protein^[3].
Nuclear receptor subfamily 1, group H, member 3's UniProt protein ID is recorded as Q9Z0Y9^[4].
Nuclear receptor subfamily 1, group H, member 3's part of is recorded as Nuclear hormone receptor-like domain superfamily^[5].
Nuclear receptor subfamily 1, group H, member 3's part of is recorded as Zinc finger, NHR/GATA-type^[6].
Nuclear receptor subfamily 1, group H, member 3's part of is recorded as liver X receptor^[7].
Nuclear receptor subfamily 1, group H, member 3's part of is recorded as Nuclear hormone receptor, ligand-binding domain, protein family^[8].
Nuclear receptor subfamily 1, group H, member 3's part of is recorded as Zinc finger, nuclear hormone receptor-type, protein family^[9].
Nuclear receptor subfamily 1, group H, member 3's has part is recorded as Nuclear hormone receptor, ligand-binding domain^[10].
Nuclear receptor subfamily 1, group H, member 3's has part is recorded as nuclear hormone receptor-type zinc finger^[11].
Nuclear receptor subfamily 1, group H, member 3's RefSeq protein ID is recorded as NP_001171201^[12].
Nuclear receptor subfamily 1, group H, member 3's RefSeq protein ID is recorded as NP_038867^[13].
Nuclear receptor subfamily 1, group H, member 3's RefSeq protein ID is recorded as XP_006499230^[14].
Nuclear receptor subfamily 1, group H, member 3's RefSeq protein ID is recorded as XP_006499231^[15].
Nuclear receptor subfamily 1, group H, member 3's RefSeq protein ID is recorded as NP_001342208^[16].
Nuclear receptor subfamily 1, group H, member 3's RefSeq protein ID is recorded as XP_030105325^[17].
Nuclear receptor subfamily 1, group H, member 3's PDB structure ID is recorded as 2ACL^[18].
Nuclear receptor subfamily 1, group H, member 3's PDB structure ID is recorded as 3FAL^[19].
Nuclear receptor subfamily 1, group H, member 3's PDB structure ID is recorded as 3FC6^[20].
Nuclear receptor subfamily 1, group H, member 3's molecular function is recorded as DNA binding^[21].
Nuclear receptor subfamily 1, group H, member 3's molecular function is recorded as DNA-binding transcription factor activity^[22].
Nuclear receptor subfamily 1, group H, member 3's molecular function is recorded as sterol response element binding^[23].
Nuclear receptor subfamily 1, group H, member 3's molecular function is recorded as zinc ion binding^[24].
Nuclear receptor subfamily 1, group H, member 3's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[25].
Nuclear receptor subfamily 1, group H, member 3's molecular function is recorded as metal ion binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Nuclear hormone receptor-like domain superfamily, Zinc finger, NHR/GATA-type, liver X receptor, Nuclear hormone receptor, ligand-binding domain, protein family, Zinc finger, nuclear hormone receptor-type, protein family

Properties

Biological process negative regulation of proteolysis, positive regulation of triglyceride biosynthetic process, positive regulation of protein metabolic process, positive regulation of cholesterol transport, regulation of transcription, DNA-templated, cellular lipid metabolic process, negative regulation of secretion of lysosomal enzymes, sterol homeostasis, response to progesterone, negative regulation of macrophage activation, positive regulation of lipoprotein lipase activity, negative regulation of transcription by RNA polymerase II, positive regulation of fatty acid biosynthetic process, transcription, DNA-templated, apoptotic cell clearance, positive regulation of transcription, DNA-templated, negative regulation of cholesterol storage, negative regulation of pinocytosis, fatty acid biosynthetic process, positive regulation of cholesterol efflux, lipid homeostasis, positive regulation of toll-like receptor 4 signaling pathway, negative regulation of lipid transport, negative regulation of transcription, DNA-templated, cellular response to lipopolysaccharide, negative regulation of inflammatory response, triglyceride homeostasis, positive regulation of transcription by RNA polymerase II, steroid hormone mediated signaling pathway, negative regulation of pancreatic juice secretion, transcription by RNA polymerase II, intracellular receptor signaling pathway, cholesterol homeostasis, negative regulation of transcription by RNA polymerase II, lipid metabolism, multicellular organism development, cell differentiation, cholesterol homeostasis, positive regulation of transcription by RNA polymerase II, negative regulation of inflammatory response, lipid homeostasis, cellular response to lipopolysaccharide, negative regulation of cold-induced thermogenesis

Cell component receptor complex, RNA polymerase II transcription regulator complex, nucleus, cytoplasm, nucleus, cytoplasm, RNA polymerase II transcription regulator complex

Encoded by Nr1h3

Found in taxon house mouse

Has part(s) Nuclear hormone receptor, ligand-binding domain, nuclear hormone receptor-type zinc finger

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, DNA-binding transcription factor activity, sterol response element binding, zinc ion binding, DNA-binding transcription activator activity, RNA polymerase II-specific, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, steroid hormone receptor activity, nuclear receptor activity, protein binding, transcription coactivator activity, sequence-specific DNA binding, retinoid X receptor binding, protein heterodimerization activity, transcription cis-regulatory region binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, transcription factor binding, nuclear receptor coactivator activity, signaling receptor activity

External References (4)

Ensembl protein id ENSMUSP00000002177, ENSMUSP00000106986, ENSMUSP00000106988, ENSMUSP00000106987

Pdb structure id 2ACL, 3FAL, 3FC6

Refseq protein id NP_001171201, NP_038867, XP_006499230, XP_006499231, NP_001342208, XP_030105325

Uniprot protein id Q9Z0Y9

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Nuclear receptor subfamily 1, group H, member 3 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Nuclear receptor subfamily 1, group H, member 3 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Nuclear receptor subfamily 1, group H, member 3 — UniProt protein ID (P352): Q9Z0Y9. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Nuclear receptor subfamily 1, group H, member 3 — part of (P361): Nuclear hormone receptor-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Nuclear receptor subfamily 1, group H, member 3 — part of (P361): Zinc finger, NHR/GATA-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Nuclear receptor subfamily 1, group H, member 3 — part of (P361): liver X receptor. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Nuclear receptor subfamily 1, group H, member 3 — part of (P361): Nuclear hormone receptor, ligand-binding domain, protein family. wikidata.org.
[9] ↑ Nuclear receptor subfamily 1, group H, member 3 — part of (P361): Zinc finger, nuclear hormone receptor-type, protein family. wikidata.org.
[10] ↑ Nuclear receptor subfamily 1, group H, member 3 — has part(s) (P527): Nuclear hormone receptor, ligand-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Nuclear receptor subfamily 1, group H, member 3 — has part(s) (P527): nuclear hormone receptor-type zinc finger. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Nuclear receptor subfamily 1, group H, member 3 — RefSeq protein ID (P637): NP_001171201. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ Nuclear receptor subfamily 1, group H, member 3 — RefSeq protein ID (P637): NP_038867. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ Nuclear receptor subfamily 1, group H, member 3 — RefSeq protein ID (P637): XP_006499230. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ Nuclear receptor subfamily 1, group H, member 3 — RefSeq protein ID (P637): XP_006499231. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ Nuclear receptor subfamily 1, group H, member 3 — RefSeq protein ID (P637): NP_001342208. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ Nuclear receptor subfamily 1, group H, member 3 — RefSeq protein ID (P637): XP_030105325. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ Nuclear receptor subfamily 1, group H, member 3 — PDB structure ID (P638): 2ACL. Q905695. Retrieved 2016-08-10. wikidata.org.
[19] ↑ Nuclear receptor subfamily 1, group H, member 3 — PDB structure ID (P638): 3FAL. Q905695. Retrieved 2016-08-10. wikidata.org.
[20] ↑ Nuclear receptor subfamily 1, group H, member 3 — PDB structure ID (P638): 3FC6. Q905695. Retrieved 2016-08-10. wikidata.org.
[21] ↑ Nuclear receptor subfamily 1, group H, member 3 — molecular function (P680): DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Nuclear receptor subfamily 1, group H, member 3 — molecular function (P680): DNA-binding transcription factor activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Nuclear receptor subfamily 1, group H, member 3 — molecular function (P680): sterol response element binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Nuclear receptor subfamily 1, group H, member 3 — molecular function (P680): zinc ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Nuclear receptor subfamily 1, group H, member 3 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Nuclear receptor subfamily 1, group H, member 3 — molecular function (P680): metal ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Nuclear receptor subfamily 1, group H, member 3 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Nuclear receptor subfamily 1, group H, member 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-3-q21989817

MLA

“Nuclear receptor subfamily 1, group H, member 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-3-q21989817.

BibTeX

@misc{4ortxyz_nuclear-receptor-subfamily-1-group-h-member-3-q21989817_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Nuclear receptor subfamily 1, group H, member 3}}, year = {2026}, url = {https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-3-q21989817}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Nuclear receptor subfamily 1, group H, member 3 — https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-3-q21989817 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-3-q21989817 · Last refreshed: May 3, 2026