Nuclear receptor subfamily 1, group H, member 2

mammalian protein found in Mus musculus

Protein protein Q21989816

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Nuclear receptor subfamily 1, group H, member 2

Summary

Nuclear receptor subfamily 1, group H, member 2 is a protein^[1].

Key Facts

Nuclear receptor subfamily 1, group H, member 2's instance of is recorded as protein^[2].
Nuclear receptor subfamily 1, group H, member 2's subclass of is recorded as protein^[3].
Nuclear receptor subfamily 1, group H, member 2's UniProt protein ID is recorded as Friedrich Rückert^[4].
Nuclear receptor subfamily 1, group H, member 2's part of is recorded as Nuclear hormone receptor-like domain superfamily^[5].
Nuclear receptor subfamily 1, group H, member 2's part of is recorded as Zinc finger, NHR/GATA-type^[6].
Nuclear receptor subfamily 1, group H, member 2's part of is recorded as liver X receptor^[7].
Nuclear receptor subfamily 1, group H, member 2's part of is recorded as Nuclear hormone receptor, ligand-binding domain, protein family^[8].
Nuclear receptor subfamily 1, group H, member 2's part of is recorded as Zinc finger, nuclear hormone receptor-type, protein family^[9].
Nuclear receptor subfamily 1, group H, member 2's has part is recorded as Nuclear hormone receptor, ligand-binding domain^[10].
Nuclear receptor subfamily 1, group H, member 2's has part is recorded as nuclear hormone receptor-type zinc finger^[11].
Nuclear receptor subfamily 1, group H, member 2's RefSeq protein ID is recorded as NP_001272446^[12].
Nuclear receptor subfamily 1, group H, member 2's RefSeq protein ID is recorded as NP_001272447^[13].
Nuclear receptor subfamily 1, group H, member 2's RefSeq protein ID is recorded as NP_001272448^[14].
Nuclear receptor subfamily 1, group H, member 2's RefSeq protein ID is recorded as NP_033499^[15].
Nuclear receptor subfamily 1, group H, member 2's RefSeq protein ID is recorded as XP_006540867^[16].
Nuclear receptor subfamily 1, group H, member 2's RefSeq protein ID is recorded as XP_017177615^[17].
Nuclear receptor subfamily 1, group H, member 2's RefSeq protein ID is recorded as XP_030098238^[18].
Nuclear receptor subfamily 1, group H, member 2's molecular function is recorded as DNA binding^[19].
Nuclear receptor subfamily 1, group H, member 2's molecular function is recorded as DNA-binding transcription factor activity^[20].
Nuclear receptor subfamily 1, group H, member 2's molecular function is recorded as ATPase binding^[21].
Nuclear receptor subfamily 1, group H, member 2's molecular function is recorded as zinc ion binding^[22].
Nuclear receptor subfamily 1, group H, member 2's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[23].
Nuclear receptor subfamily 1, group H, member 2's molecular function is recorded as metal ion binding^[24].
Nuclear receptor subfamily 1, group H, member 2's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding^[25].
Nuclear receptor subfamily 1, group H, member 2's molecular function is recorded as steroid hormone receptor activity^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Nuclear hormone receptor-like domain superfamily, Zinc finger, NHR/GATA-type, liver X receptor, Nuclear hormone receptor, ligand-binding domain, protein family, Zinc finger, nuclear hormone receptor-type, protein family

Properties

Biological process positive regulation of high-density lipoprotein particle assembly, negative regulation of proteolysis, positive regulation of triglyceride biosynthetic process, positive regulation of protein metabolic process, positive regulation of cholesterol transport, regulation of transcription, DNA-templated, cellular lipid metabolic process, regulation of transcription by RNA polymerase II, positive regulation of secretion of lysosomal enzymes, positive regulation of lipid storage, positive regulation of lipoprotein lipase activity, negative regulation of transcription by RNA polymerase II, positive regulation of fatty acid biosynthetic process, transcription, DNA-templated, positive regulation of transcription, DNA-templated, negative regulation of cholesterol storage, negative regulation of pinocytosis, positive regulation of cholesterol efflux, positive regulation of pancreatic juice secretion, lipid homeostasis, negative regulation of lipid transport, negative regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, steroid hormone mediated signaling pathway, transcription by RNA polymerase II, cholesterol homeostasis, positive regulation of gene expression, negative regulation of gene expression, retinoic acid receptor signaling pathway, negative regulation of transcription by RNA polymerase II, lipid metabolism, multicellular organism development, cell differentiation, cholesterol homeostasis, positive regulation of transcription by RNA polymerase II, lipid homeostasis, cellular response to lipopolysaccharide, negative regulation of cold-induced thermogenesis

Cell component cytoplasm, nucleus, nucleus, RNA polymerase II transcription regulator complex

Encoded by Nr1h2

Found in taxon house mouse

Has part(s) Nuclear hormone receptor, ligand-binding domain, nuclear hormone receptor-type zinc finger

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, DNA-binding transcription factor activity, ATPase binding, zinc ion binding, DNA-binding transcription activator activity, RNA polymerase II-specific, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, steroid hormone receptor activity, apolipoprotein A-I receptor binding, nuclear receptor activity, protein binding, sequence-specific DNA binding, retinoid X receptor binding, transcription cis-regulatory region binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, transcription factor binding, nuclear receptor coactivator activity, signaling receptor activity

External References (3)

Ensembl protein id ENSMUSP00000073188, ENSMUSP00000103545, ENSMUSP00000126788, ENSMUSP00000103543, ENSMUSP00000103544, ENSMUSP00000146455, ENSMUSP00000146466, ENSMUSP00000146517, ENSMUSP00000146601, ENSMUSP00000146826, ENSMUSP00000147076

Refseq protein id NP_001272446, NP_001272447, NP_001272448, NP_033499, XP_006540867, XP_017177615, XP_030098238

Uniprot protein id Friedrich Rückert

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Nuclear receptor subfamily 1, group H, member 2 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Nuclear receptor subfamily 1, group H, member 2 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Nuclear receptor subfamily 1, group H, member 2 — UniProt protein ID (P352): Friedrich Rückert. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Nuclear receptor subfamily 1, group H, member 2 — part of (P361): Nuclear hormone receptor-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Nuclear receptor subfamily 1, group H, member 2 — part of (P361): Zinc finger, NHR/GATA-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Nuclear receptor subfamily 1, group H, member 2 — part of (P361): liver X receptor. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Nuclear receptor subfamily 1, group H, member 2 — part of (P361): Nuclear hormone receptor, ligand-binding domain, protein family. wikidata.org.
[9] ↑ Nuclear receptor subfamily 1, group H, member 2 — part of (P361): Zinc finger, nuclear hormone receptor-type, protein family. wikidata.org.
[10] ↑ Nuclear receptor subfamily 1, group H, member 2 — has part(s) (P527): Nuclear hormone receptor, ligand-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Nuclear receptor subfamily 1, group H, member 2 — has part(s) (P527): nuclear hormone receptor-type zinc finger. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Nuclear receptor subfamily 1, group H, member 2 — RefSeq protein ID (P637): NP_001272446. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ Nuclear receptor subfamily 1, group H, member 2 — RefSeq protein ID (P637): NP_001272447. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ Nuclear receptor subfamily 1, group H, member 2 — RefSeq protein ID (P637): NP_001272448. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ Nuclear receptor subfamily 1, group H, member 2 — RefSeq protein ID (P637): NP_033499. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ Nuclear receptor subfamily 1, group H, member 2 — RefSeq protein ID (P637): XP_006540867. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ Nuclear receptor subfamily 1, group H, member 2 — RefSeq protein ID (P637): XP_017177615. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ Nuclear receptor subfamily 1, group H, member 2 — RefSeq protein ID (P637): XP_030098238. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ Nuclear receptor subfamily 1, group H, member 2 — molecular function (P680): DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Nuclear receptor subfamily 1, group H, member 2 — molecular function (P680): DNA-binding transcription factor activity. Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Nuclear receptor subfamily 1, group H, member 2 — molecular function (P680): ATPase binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Nuclear receptor subfamily 1, group H, member 2 — molecular function (P680): zinc ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Nuclear receptor subfamily 1, group H, member 2 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Nuclear receptor subfamily 1, group H, member 2 — molecular function (P680): metal ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Nuclear receptor subfamily 1, group H, member 2 — molecular function (P680): RNA polymerase II cis-regulatory region sequence-specific DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Nuclear receptor subfamily 1, group H, member 2 — molecular function (P680): steroid hormone receptor activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Nuclear receptor subfamily 1, group H, member 2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Nuclear receptor subfamily 1, group H, member 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-2-q21989816

MLA

“Nuclear receptor subfamily 1, group H, member 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-2-q21989816.

BibTeX

@misc{4ortxyz_nuclear-receptor-subfamily-1-group-h-member-2-q21989816_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Nuclear receptor subfamily 1, group H, member 2}}, year = {2026}, url = {https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-2-q21989816}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Nuclear receptor subfamily 1, group H, member 2 — https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-2-q21989816 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-2-q21989816 · Last refreshed: May 3, 2026