MYD88 innate immune signal transduction adaptor

mammalian protein found in Homo sapiens

Protein protein Q1500000

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MYD88 innate immune signal transduction adaptor

Summary

MYD88 innate immune signal transduction adaptor is a protein^[1].

Key Facts

MYD88 innate immune signal transduction adaptor's instance of is recorded as protein^[2].
MYD88 innate immune signal transduction adaptor's UniProt protein ID is recorded as Joseph Knauer^[3].
MYD88 innate immune signal transduction adaptor's part of is recorded as Myeloid differentiation primary response protein MyD88^[4].
MYD88 innate immune signal transduction adaptor's part of is recorded as Toll/interleukin-1 receptor homology (TIR) domain superfamily^[5].
MYD88 innate immune signal transduction adaptor's part of is recorded as Death-like domain superfamily^[6].
MYD88 innate immune signal transduction adaptor's part of is recorded as Death domain, protein family^[7].
MYD88 innate immune signal transduction adaptor's part of is recorded as MyD88, death domain, protein family^[8].
MYD88 innate immune signal transduction adaptor's part of is recorded as Toll/interleukin-1 receptor homology (TIR) domain, protein family^[9].
MYD88 innate immune signal transduction adaptor's has part is recorded as death domain^[10].
MYD88 innate immune signal transduction adaptor's has part is recorded as Toll/interleukin-1 receptor homology (TIR) domain^[11].
MYD88 innate immune signal transduction adaptor's has part is recorded as MyD88, death domain^[12].
MYD88 innate immune signal transduction adaptor's RefSeq protein ID is recorded as NP_001166037^[13].
MYD88 innate immune signal transduction adaptor's RefSeq protein ID is recorded as NP_001166038^[14].
MYD88 innate immune signal transduction adaptor's RefSeq protein ID is recorded as NP_001166039^[15].
MYD88 innate immune signal transduction adaptor's RefSeq protein ID is recorded as NP_001166040^[16].
MYD88 innate immune signal transduction adaptor's RefSeq protein ID is recorded as NP_002459^[17].
MYD88 innate immune signal transduction adaptor's RefSeq protein ID is recorded as NP_001352805^[18].
MYD88 innate immune signal transduction adaptor's RefSeq protein ID is recorded as NP_001352806^[19].
MYD88 innate immune signal transduction adaptor's RefSeq protein ID is recorded as NP_001361716^[20].
MYD88 innate immune signal transduction adaptor's RefSeq protein ID is recorded as NP_001361717^[21].
MYD88 innate immune signal transduction adaptor's PDB structure ID is recorded as 2JS7^[22].
MYD88 innate immune signal transduction adaptor's PDB structure ID is recorded as 2Z5V^[23].
MYD88 innate immune signal transduction adaptor's PDB structure ID is recorded as 3MOP^[24].
MYD88 innate immune signal transduction adaptor's PDB structure ID is recorded as 4DOM^[25].
MYD88 innate immune signal transduction adaptor's PDB structure ID is recorded as 4EO7^[26].

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Quick Facts

Instance of protein

Part of Myeloid differentiation primary response protein MyD88, Toll/interleukin-1 receptor homology (TIR) domain superfamily, Death-like domain superfamily, Death domain, protein family, MyD88, death domain, protein family, Toll/interleukin-1 receptor homology (TIR) domain, protein family

Properties

Biological process response to interleukin-1, immune system process, negative regulation of apoptotic process, MyD88-dependent toll-like receptor signaling pathway, toll-like receptor signaling pathway, cell surface receptor signaling pathway, cellular response to mechanical stimulus, regulation of inflammatory response, positive regulation of interleukin-6 production, positive regulation of I-kappaB kinase/NF-kappaB signaling, toll-like receptor 9 signaling pathway, positive regulation of interleukin-17 production, inflammatory response, 3'-UTR-mediated mRNA stabilization, positive regulation of type I interferon production, positive regulation of interleukin-23 production, signal transduction, defense response to Gram-positive bacterium, positive regulation of NF-kappaB transcription factor activity, apoptotic process, innate immune response, type I interferon signaling pathway, positive regulation of gene expression, positive regulation of interleukin-8 production, defense response to bacterium, interleukin-1-mediated signaling pathway, cellular response to oxidised low-density lipoprotein particle stimulus, positive regulation of cytokine production involved in inflammatory response, phagocytosis, Toll signaling pathway, innate immune response, defense response to Gram-positive bacterium

Cell component cytosol, plasma membrane, endosome membrane, cytoplasm, nucleus, nucleus, plasma membrane

Encoded by MYD88

Exact match purl.uniprot.org

Found in taxon Homo sapiens

Has part(s) death domain, Toll/interleukin-1 receptor homology (TIR) domain, MyD88, death domain

Imported from wholeness_audit_2026-05-02

Molecular function death receptor binding, protein binding, TIR domain binding, identical protein binding, protein self-association, Toll-like receptor binding

External References (4)

Ensembl protein id ENSP00000390565, ENSP00000417848, ENSP00000379625, ENSP00000389979, ENSP00000391753, ENSP00000401399, ENSP00000496950, ENSP00000497991, ENSP00000498321, ENSP00000498360, ENSP00000499012, ENSP00000498576

Pdb structure id 2JS7, 2Z5V, 3MOP, 4DOM, 4EO7

Refseq protein id NP_001166037, NP_001166038, NP_001166039, NP_001166040, NP_002459, NP_001352805, NP_001352806, NP_001361716, NP_001361717

Uniprot protein id Joseph Knauer

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ MYD88 innate immune signal transduction adaptor — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ MYD88 innate immune signal transduction adaptor — UniProt protein ID (P352): Joseph Knauer. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ MYD88 innate immune signal transduction adaptor — part of (P361): Myeloid differentiation primary response protein MyD88. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ MYD88 innate immune signal transduction adaptor — part of (P361): Toll/interleukin-1 receptor homology (TIR) domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ MYD88 innate immune signal transduction adaptor — part of (P361): Death-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ MYD88 innate immune signal transduction adaptor — part of (P361): Death domain, protein family. wikidata.org.
[8] ↑ MYD88 innate immune signal transduction adaptor — part of (P361): MyD88, death domain, protein family. wikidata.org.
[9] ↑ MYD88 innate immune signal transduction adaptor — part of (P361): Toll/interleukin-1 receptor homology (TIR) domain, protein family. wikidata.org.
[10] ↑ MYD88 innate immune signal transduction adaptor — has part(s) (P527): death domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ MYD88 innate immune signal transduction adaptor — has part(s) (P527): Toll/interleukin-1 receptor homology (TIR) domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ MYD88 innate immune signal transduction adaptor — has part(s) (P527): MyD88, death domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ MYD88 innate immune signal transduction adaptor — RefSeq protein ID (P637): NP_001166037. Q20641742. Retrieved 2020-05-30. wikidata.org.
[14] ↑ MYD88 innate immune signal transduction adaptor — RefSeq protein ID (P637): NP_001166038. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ MYD88 innate immune signal transduction adaptor — RefSeq protein ID (P637): NP_001166039. Q20641742. Retrieved 2020-05-30. wikidata.org.
[16] ↑ MYD88 innate immune signal transduction adaptor — RefSeq protein ID (P637): NP_001166040. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ MYD88 innate immune signal transduction adaptor — RefSeq protein ID (P637): NP_002459. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ MYD88 innate immune signal transduction adaptor — RefSeq protein ID (P637): NP_001352805. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ MYD88 innate immune signal transduction adaptor — RefSeq protein ID (P637): NP_001352806. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ MYD88 innate immune signal transduction adaptor — RefSeq protein ID (P637): NP_001361716. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ MYD88 innate immune signal transduction adaptor — RefSeq protein ID (P637): NP_001361717. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ MYD88 innate immune signal transduction adaptor — PDB structure ID (P638): 2JS7. Q905695. Retrieved 2016-08-09. wikidata.org.
[23] ↑ MYD88 innate immune signal transduction adaptor — PDB structure ID (P638): 2Z5V. Q905695. Retrieved 2016-08-09. wikidata.org.
[24] ↑ MYD88 innate immune signal transduction adaptor — PDB structure ID (P638): 3MOP. Q905695. Retrieved 2016-08-09. wikidata.org.
[25] ↑ MYD88 innate immune signal transduction adaptor — PDB structure ID (P638): 4DOM. Q905695. Retrieved 2016-08-09. wikidata.org.
[26] ↑ MYD88 innate immune signal transduction adaptor — PDB structure ID (P638): 4EO7. Q905695. Retrieved 2016-08-09. wikidata.org.

Class ancestry

[1] ↑ MYD88 innate immune signal transduction adaptor is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). MYD88 innate immune signal transduction adaptor. Retrieved May 3, 2026, from https://4ort.xyz/entity/myd88-innate-immune-signal-transduction-adaptor

MLA

“MYD88 innate immune signal transduction adaptor.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/myd88-innate-immune-signal-transduction-adaptor.

BibTeX

@misc{4ortxyz_myd88-innate-immune-signal-transduction-adaptor_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{MYD88 innate immune signal transduction adaptor}}, year = {2026}, url = {https://4ort.xyz/entity/myd88-innate-immune-signal-transduction-adaptor}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): MYD88 innate immune signal transduction adaptor — https://4ort.xyz/entity/myd88-innate-immune-signal-transduction-adaptor (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/myd88-innate-immune-signal-transduction-adaptor · Last refreshed: May 3, 2026