Mitogen-activated protein kinase kinase 5

mammalian protein found in Mus musculus

Protein protein Q21984678

Press Enter · cited answer in seconds

Mitogen-activated protein kinase kinase 5

Summary

Mitogen-activated protein kinase kinase 5 is a protein^[1].

Key Facts

Mitogen-activated protein kinase kinase 5's instance of is recorded as protein^[2].
Mitogen-activated protein kinase kinase 5's subclass of is recorded as protein^[3].
Mitogen-activated protein kinase kinase 5's UniProt protein ID is recorded as Q9WVS7^[4].
Mitogen-activated protein kinase kinase 5's part of is recorded as Protein kinase-like domain superfamily^[5].
Mitogen-activated protein kinase kinase 5's part of is recorded as Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain, protein family^[6].
Mitogen-activated protein kinase kinase 5's part of is recorded as PB1 domain, protein family^[7].
Mitogen-activated protein kinase kinase 5's part of is recorded as Protein kinase domain, protein family^[8].
Mitogen-activated protein kinase kinase 5's part of is recorded as Protein kinase, ATP binding site, protein family^[9].
Mitogen-activated protein kinase kinase 5's part of is recorded as Serine/threonine-protein kinase, active site, protein family^[10].
Mitogen-activated protein kinase kinase 5's has part is recorded as PB1 domain^[11].
Mitogen-activated protein kinase kinase 5's has part is recorded as serine/threonine-protein kinase, active site^[12].
Mitogen-activated protein kinase kinase 5's has part is recorded as protein kinase domain^[13].
Mitogen-activated protein kinase kinase 5's has part is recorded as protein kinase, ATP binding site^[14].
Mitogen-activated protein kinase kinase 5's has part is recorded as Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain^[15].
Mitogen-activated protein kinase kinase 5's RefSeq protein ID is recorded as NP_035970^[16].
Mitogen-activated protein kinase kinase 5's RefSeq protein ID is recorded as XP_006511209^[17].
Mitogen-activated protein kinase kinase 5's RefSeq protein ID is recorded as XP_011241042^[18].
Mitogen-activated protein kinase kinase 5's RefSeq protein ID is recorded as NP_001351421^[19].
Mitogen-activated protein kinase kinase 5's RefSeq protein ID is recorded as NP_001351422^[20].
Mitogen-activated protein kinase kinase 5's RefSeq protein ID is recorded as NP_001351423^[21].
Mitogen-activated protein kinase kinase 5's RefSeq protein ID is recorded as XP_030100214^[22].
Mitogen-activated protein kinase kinase 5's RefSeq protein ID is recorded as XP_036010824^[23].
Mitogen-activated protein kinase kinase 5's RefSeq protein ID is recorded as XP_036010825^[24].
Mitogen-activated protein kinase kinase 5's RefSeq protein ID is recorded as XP_036010826^[25].
Mitogen-activated protein kinase kinase 5's PDB structure ID is recorded as 1WI0^[26].

⭐ Popularity Graph

0/100 long tail

Quick Facts

Instance of protein

Subclass of protein

Part of Protein kinase-like domain superfamily, Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain, protein family, PB1 domain, protein family, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family, Serine/threonine-protein kinase, active site, protein family

Properties

Biological process phosphorylation, MAPK cascade, development of the heart, peptidyl-tyrosine phosphorylation, regulation of mitotic cell cycle, stress-activated protein kinase signaling cascade, activation of protein kinase activity, regulation of apoptotic process, negative regulation of transcription by RNA polymerase II, protein phosphorylation, positive regulation of cell growth, negative regulation of NF-kappaB transcription factor activity, negative regulation of heterotypic cell-cell adhesion, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of transcription by RNA polymerase II, positive regulation of epithelial cell proliferation, negative regulation of response to cytokine stimulus, ERK5 cascade, cellular response to growth factor stimulus, negative regulation of cell migration involved in sprouting angiogenesis, negative regulation of chemokine (C-X-C motif) ligand 2 production, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, signal transduction

Cell component cytoplasm, spindle, nucleus, cytosol

Encoded by Map2k5

Found in taxon house mouse

Has part(s) PB1 domain, serine/threonine-protein kinase, active site, protein kinase domain, protein kinase, ATP binding site, Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain

Imported from wholeness_audit_2026-05-02

Molecular function transferase activity, nucleotide binding, metal ion binding, kinase activity, protein binding, protein tyrosine kinase activity, protein serine/threonine kinase activity, protein kinase activity, ATP binding, MAP kinase kinase activity

External References (4)

Ensembl protein id ENSMUSP00000034920

Pdb structure id 1WI0

Refseq protein id NP_035970, XP_006511209, XP_011241042, NP_001351421, NP_001351422, NP_001351423, XP_030100214, XP_036010824, XP_036010825, XP_036010826

Uniprot protein id Q9WVS7

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Mitogen-activated protein kinase kinase 5 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Mitogen-activated protein kinase kinase 5 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Mitogen-activated protein kinase kinase 5 — UniProt protein ID (P352): Q9WVS7. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Mitogen-activated protein kinase kinase 5 — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Mitogen-activated protein kinase kinase 5 — part of (P361): Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain, protein family. wikidata.org.
[7] ↑ Mitogen-activated protein kinase kinase 5 — part of (P361): PB1 domain, protein family. wikidata.org.
[8] ↑ Mitogen-activated protein kinase kinase 5 — part of (P361): Protein kinase domain, protein family. wikidata.org.
[9] ↑ Mitogen-activated protein kinase kinase 5 — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[10] ↑ Mitogen-activated protein kinase kinase 5 — part of (P361): Serine/threonine-protein kinase, active site, protein family. wikidata.org.
[11] ↑ Mitogen-activated protein kinase kinase 5 — has part(s) (P527): PB1 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Mitogen-activated protein kinase kinase 5 — has part(s) (P527): serine/threonine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Mitogen-activated protein kinase kinase 5 — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Mitogen-activated protein kinase kinase 5 — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Mitogen-activated protein kinase kinase 5 — has part(s) (P527): Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Mitogen-activated protein kinase kinase 5 — RefSeq protein ID (P637): NP_035970. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ Mitogen-activated protein kinase kinase 5 — RefSeq protein ID (P637): XP_006511209. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ Mitogen-activated protein kinase kinase 5 — RefSeq protein ID (P637): XP_011241042. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ Mitogen-activated protein kinase kinase 5 — RefSeq protein ID (P637): NP_001351421. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Mitogen-activated protein kinase kinase 5 — RefSeq protein ID (P637): NP_001351422. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ Mitogen-activated protein kinase kinase 5 — RefSeq protein ID (P637): NP_001351423. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Mitogen-activated protein kinase kinase 5 — RefSeq protein ID (P637): XP_030100214. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Mitogen-activated protein kinase kinase 5 — RefSeq protein ID (P637): XP_036010824. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Mitogen-activated protein kinase kinase 5 — RefSeq protein ID (P637): XP_036010825. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Mitogen-activated protein kinase kinase 5 — RefSeq protein ID (P637): XP_036010826. Q20641742. Retrieved 2022-03-20. wikidata.org.
[26] ↑ Mitogen-activated protein kinase kinase 5 — PDB structure ID (P638): 1WI0. Q905695. Retrieved 2016-08-09. wikidata.org.

Class ancestry

[1] ↑ Mitogen-activated protein kinase kinase 5 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Mitogen-activated protein kinase kinase 5. Retrieved May 3, 2026, from https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-5-q21984678

MLA

“Mitogen-activated protein kinase kinase 5.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-5-q21984678.

BibTeX

@misc{4ortxyz_mitogen-activated-protein-kinase-kinase-5-q21984678_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Mitogen-activated protein kinase kinase 5}}, year = {2026}, url = {https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-5-q21984678}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Mitogen-activated protein kinase kinase 5 — https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-5-q21984678 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-5-q21984678 · Last refreshed: May 3, 2026