Home › Entities › 1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol › miglustat

miglustat

chemical compound
Class type of: 1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol Q425911

Facts

17 properties
Instance of
type of chemical entity
Subclass of
1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
Has use
medication
Active ingredient in
Zavesca
Canonical SMILES
CCCCN1CC(C(C(C1CO)O)O)O
Chemical formula
C₁₀H₂₁NO₄
Defined daily dose
+0.3
Isomeric SMILES
CCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O
LiverTox likelihood score
LiverTox toxicity likelihood category E
Mass
+219.147
Medical condition treated
Gaucher's disease
Physically interacts with
UDP-glucose ceramide glucosyltransferase
Pregnancy category
US pregnancy category X
Stereoisomer of
lucerastat
Stylized name
migLUstat
Subject has role
enzyme inhibitor, anti-HIV agents, glycoside hydrolase inhibitors
World Health Organisation international non-proprietary name
miglustat
🏷️ Also known as
en N-Butylmoranoline en Zavesca® en SC-48334 en N-(N-Butyl)deoxynojirimycin en N-(n-Butyl)deoxynojirimycin en BuDNJ en Butyldeoxynojirimycin en miglustat en Miglustat en Miglustatum en NB-dnj en NB-DNJ en N-butyl-1-deoxynojirimycin en N-Butyl-1-deoxynojirimycin en n-Butyl deoxynojirimycin en N-Butyl deoxynojirimycin ar ميجلوستات de Zavesca de N-Butylmoranolin de N-Butyldeoxynojirimycin
🔖 Identifiers · 34
ATC code
A16AX06
CAS Registry Number
72599-27-0
ChEBI ID
50381
ChEMBL ID
CHEMBL1029
ChemSpider ID
46764
DSSTOX compound identifier
DTXCID4025618
DSSTox substance ID
DTXSID6045618
DrugBank ID
DB00419
DrugCentral ID
1807
EC number
689-232-7
ECHA Substance Infocard ID
100.216.074
Freebase ID
/m/02w57mz
Show all 34 identifiers +22
Guide to Pharmacology Ligand ID
4841
Human Metabolome Database ID
HMDB0014563
InChI
InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1
InChIKey
UQRORFVVSGFNRO-UTINFBMNSA-N
KEGG ID
D05032
LiverTox ID
Miglustat
MeSH descriptor ID
C059896
MedlinePlus drug identifier
a604015
Microsoft Academic ID (discontinued)
2778358581
NDF-RT ID
N0000148822
PDB ligand ID
NBV
PDB structure ID
5IEF, 2V3D
Probes And Drugs ID
PD010037
PubChem CID
51634
Reaxys registry number
5862029
RxNorm CUI
402316
ScienceDirect topic ID
chemistry/miglustat
SureChEMBL ID
246893
UMLS CUI
C1321596
UNII
ADN3S497AZ
UniChem compound ID
359777
WikiProjectMed ID
Miglustat

Report an error or request removal Lineage (PROV-JSON)

🔗 Connections
Has use 1
medication
Medical condition treated 1
Gaucher's disease
Subject has role 1
enzyme inhibitor
← Drug or therapy used for treatment 1
Gaucher's disease
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Summary

miglustat is a type of chemical entity[1]. miglustat is a type of 1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol[2].

Key Facts

  • Physically interacts with: UDP-glucose ceramide glucosyltransferase[3]
  • Canonical SMILES: CCCCN1CC(C(C(C1CO)O)O)O[4]
  • Chemical formula: C₁₀H₂₁NO₄[5]
  • Has use: medication[6]
  • Isomeric SMILES: CCCCN1CC@@HOC@@HO">[7]
  • Mass: 219.147 dalton[8]
  • Medical condition treated: Gaucher's disease[9]
  • World Health Organisation international non-proprietary name: miglustat[10]
  • Subject has role: enzyme inhibitor[11], anti-HIV agents[12], glycoside hydrolase inhibitors[13]
  • Stereoisomer of: lucerastat[14]
  • Pregnancy category: US pregnancy category X[15]
  • Active ingredient in: Zavesca[16]
  • Defined daily dose: 0.3 g[17]
  • LiverTox likelihood score: LiverTox toxicity likelihood category E[18]
  • Stylized name: migLUstat[19]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  2. [4] ↑ . PubChem. Retrieved . wikidata.org.
  3. [5] ↑ . PubChem. Retrieved . wikidata.org.
  4. [2] ↑ . wikidata.org.
  5. [6] ↑ . wikidata.org.
  6. [7] ↑ . PubChem. Retrieved . wikidata.org.
  7. [8] ↑ . PubChem. Retrieved . wikidata.org.
  8. [9] ↑ . Inxight: Drugs Database. Retrieved . drugs.ncats.io. Provenance: wikidata.org.
  9. [10] ↑ . ChEBI. Retrieved . wikidata.org.
  10. [11] ↑ . Medical Subject Headings. Retrieved . wikidata.org.
  11. [12] ↑ . Medical Subject Headings. Retrieved . wikidata.org.
  12. [13] ↑ . Medical Subject Headings. Retrieved . wikidata.org.
  13. [14] ↑ . wikidata.org.
  14. [15] ↑ . wikidata.org.
  15. [16] ↑ . RxNorm. Retrieved . wikidata.org.
  16. [17] ↑ . whocc.no. whocc.no. Provenance: wikidata.org.
  17. [18] ↑ . LiverTox. Retrieved . ncbi.nlm.nih.gov. Provenance: wikidata.org.
  18. [19] ↑ . fda.gov. Retrieved . fda.gov. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). miglustat. Retrieved November 2, 2026, from https://4ort.xyz/entity/miglustat
MLA “miglustat.” 4ort.xyz Knowledge Graph, 4ort.xyz, 2 Nov. 2026, https://4ort.xyz/entity/miglustat.
BibTeX @misc{4ortxyz_miglustat_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{miglustat}}, year = {2026}, url = {https://4ort.xyz/entity/miglustat}, note = {Accessed: 2026-11-02}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): miglustat — https://4ort.xyz/entity/miglustat (retrieved 2026-11-02)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 20w ago · Nabbegat · 2026-06-19 view diff on Wikidata ↗
    Defined daily dose → {'unit': 'Q41803', 'amount': '+0.3'}
    Stereoisomer of → lucerastat
    Instance of → type of chemical entity
    Has use → medication
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||tr */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/37300|batch #37300]]"
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