Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

mammalian protein found in Mus musculus

Protein protein Q21494887

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Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

Summary

Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like is a protein^[1].

Key Facts

Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's instance of is recorded as protein^[2].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's subclass of is recorded as protein^[3].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's UniProt protein ID is recorded as Q3V3R1^[4].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's part of is recorded as formate-tetrahydrofolate ligase^[5].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's part of is recorded as NAD(P)-binding domain superfamily^[6].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's part of is recorded as Tetrahydrofolate dehydrogenase/cyclohydrolase^[7].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's part of is recorded as P-loop containing nucleoside triphosphate hydrolase^[8].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's part of is recorded as Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, protein family^[9].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's part of is recorded as Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain, protein family^[10].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's part of is recorded as Formate-tetrahydrofolate ligase, FTHFS, conserved site, protein family^[11].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's has part is recorded as Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain^[12].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's has part is recorded as Formate-tetrahydrofolate ligase, FTHFS, conserved site^[13].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's has part is recorded as Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain^[14].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's RefSeq protein ID is recorded as NP_001164256^[15].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's RefSeq protein ID is recorded as NP_001164257^[16].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's RefSeq protein ID is recorded as NP_758512^[17].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's RefSeq protein ID is recorded as XP_036011688^[18].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's RefSeq protein ID is recorded as XP_036011689^[19].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's PDB structure ID is recorded as 2EO2^[20].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's molecular function is recorded as nucleotide binding^[21].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's molecular function is recorded as formate-tetrahydrofolate ligase activity^[22].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's molecular function is recorded as ligase activity^[23].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's molecular function is recorded as ATP binding^[24].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's molecular function is recorded as protein homodimerization activity^[25].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like's molecular function is recorded as methenyltetrahydrofolate cyclohydrolase activity^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of formate-tetrahydrofolate ligase, NAD(P)-binding domain superfamily, Tetrahydrofolate dehydrogenase/cyclohydrolase, P-loop containing nucleoside triphosphate hydrolase, Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, protein family, Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain, protein family, Formate-tetrahydrofolate ligase, FTHFS, conserved site, protein family

Properties

Biological process embryonic neurocranium morphogenesis, embryonic viscerocranium morphogenesis, tetrahydrofolate interconversion, neural tube closure, formate metabolic process, tetrahydrofolate metabolic process, folic acid-containing compound metabolic process, one-carbon metabolic process, purine nucleobase biosynthetic process, 10-formyltetrahydrofolate biosynthetic process

Cell component mitochondrion, cytoplasm, mitochondrion

Encoded by Mthfd1l

Found in taxon house mouse

Has part(s) Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain, Formate-tetrahydrofolate ligase, FTHFS, conserved site, Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain

Imported from wholeness_audit_2026-05-02

Molecular function nucleotide binding, formate-tetrahydrofolate ligase activity, ligase activity, ATP binding, protein homodimerization activity, methenyltetrahydrofolate cyclohydrolase activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity

External References (4)

Ensembl protein id ENSMUSP00000036178, ENSMUSP00000112870, ENSMUSP00000112897

Pdb structure id 2EO2

Refseq protein id NP_001164256, NP_001164257, NP_758512, XP_036011688, XP_036011689

Uniprot protein id Q3V3R1

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — UniProt protein ID (P352): Q3V3R1. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — part of (P361): formate-tetrahydrofolate ligase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — part of (P361): NAD(P)-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — part of (P361): Tetrahydrofolate dehydrogenase/cyclohydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — part of (P361): P-loop containing nucleoside triphosphate hydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — part of (P361): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, protein family. wikidata.org.
[10] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — part of (P361): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain, protein family. wikidata.org.
[11] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — part of (P361): Formate-tetrahydrofolate ligase, FTHFS, conserved site, protein family. wikidata.org.
[12] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — has part(s) (P527): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — has part(s) (P527): Formate-tetrahydrofolate ligase, FTHFS, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — has part(s) (P527): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — RefSeq protein ID (P637): NP_001164256. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — RefSeq protein ID (P637): NP_001164257. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — RefSeq protein ID (P637): NP_758512. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — RefSeq protein ID (P637): XP_036011688. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — RefSeq protein ID (P637): XP_036011689. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — PDB structure ID (P638): 2EO2. Q905695. Retrieved 2016-08-09. wikidata.org.
[21] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — molecular function (P680): formate-tetrahydrofolate ligase activity. Human mitochondrial C1-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary calls. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — molecular function (P680): ligase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — molecular function (P680): ATP binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — molecular function (P680): protein homodimerization activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — molecular function (P680): methenyltetrahydrofolate cyclohydrolase activity. GOA. Retrieved 2018-01-31. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

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BibTeX

@misc{4ortxyz_methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like-q21494887_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like}}, year = {2026}, url = {https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like-q21494887}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like — https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like-q21494887 (retrieved 2026-05-03)

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