Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like

mammalian protein found in Homo sapiens

Protein protein Q21131857

Press Enter · cited answer in seconds

Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like

Summary

Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like is a protein^[1].

Key Facts

Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's instance of is recorded as protein^[2].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's UniProt protein ID is recorded as Q6UB35^[3].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's part of is recorded as formate-tetrahydrofolate ligase^[4].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's part of is recorded as NAD(P)-binding domain superfamily^[5].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's part of is recorded as Tetrahydrofolate dehydrogenase/cyclohydrolase^[6].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's part of is recorded as P-loop containing nucleoside triphosphate hydrolase^[7].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's part of is recorded as Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, protein family^[8].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's part of is recorded as Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain, protein family^[9].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's part of is recorded as Formate-tetrahydrofolate ligase, FTHFS, conserved site, protein family^[10].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's has part is recorded as Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain^[11].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's has part is recorded as Formate-tetrahydrofolate ligase, FTHFS, conserved site^[12].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's has part is recorded as Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain^[13].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as NP_001229696^[14].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as NP_001229697^[15].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as NP_001229698^[16].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as NP_056255^[17].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as XP_005266964^[18].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as XP_005266968^[19].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as XP_011534031^[20].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as XP_011534032^[21].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as XP_011534033^[22].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as XP_011534034^[23].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as XP_011534035^[24].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as XP_011534036^[25].
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like's RefSeq protein ID is recorded as XP_011534039^[26].

⭐ Popularity Graph

0/100 long tail

Quick Facts

Instance of protein

Part of formate-tetrahydrofolate ligase, NAD(P)-binding domain superfamily, Tetrahydrofolate dehydrogenase/cyclohydrolase, P-loop containing nucleoside triphosphate hydrolase, Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, protein family, Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain, protein family, Formate-tetrahydrofolate ligase, FTHFS, conserved site, protein family

Properties

Biological process formate metabolic process, embryonic neurocranium morphogenesis, tetrahydrofolate interconversion, tetrahydrofolate metabolic process, neural tube closure, folic acid metabolic process, embryonic viscerocranium morphogenesis, folic acid-containing compound metabolic process, purine nucleobase biosynthetic process, 10-formyltetrahydrofolate biosynthetic process, one-carbon metabolic process, 10-formyltetrahydrofolate biosynthetic process

Cell component membrane, mitochondrial matrix, mitochondrion, cytoplasm, mitochondrion, membrane

Encoded by MTHFD1L

Found in taxon Homo sapiens

Has part(s) Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, Formate-tetrahydrofolate ligase, FTHFS, conserved site, Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain

Imported from wholeness_audit_2026-05-02

Molecular function nucleotide binding, protein homodimerization activity, methenyltetrahydrofolate cyclohydrolase activity, formate-tetrahydrofolate ligase activity, ligase activity, ATP binding, methylenetetrahydrofolate dehydrogenase (NADP+) activity, formate-tetrahydrofolate ligase activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity, formate-tetrahydrofolate ligase activity

External References (4)

Ensembl protein id ENSP00000356276, ENSP00000356290, ENSP00000356277, ENSP00000391022, ENSP00000395158, ENSP00000399804, ENSP00000400776, ENSP00000407070, ENSP00000478253, ENSP00000479539

Pdb structure id 2EO2

Refseq protein id NP_001229696, NP_001229697, NP_001229698, NP_056255, XP_005266964, XP_005266968, XP_011534031, XP_011534032, XP_011534033, XP_011534034, XP_011534035, XP_011534036, XP_011534039, XP_011534040, XP_016866191, XP_016866192, XP_016866194, NP_001337415, NP_001337416, NP_001337417, NP_001337418, NP_001337419, NP_001337420, NP_001337421, NP_001337422, XP_024302163, XP_024302164

Uniprot protein id Q6UB35

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — UniProt protein ID (P352): Q6UB35. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — part of (P361): formate-tetrahydrofolate ligase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — part of (P361): NAD(P)-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — part of (P361): Tetrahydrofolate dehydrogenase/cyclohydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — part of (P361): P-loop containing nucleoside triphosphate hydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — part of (P361): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, protein family. wikidata.org.
[9] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — part of (P361): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain, protein family. wikidata.org.
[10] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — part of (P361): Formate-tetrahydrofolate ligase, FTHFS, conserved site, protein family. wikidata.org.
[11] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — has part(s) (P527): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — has part(s) (P527): Formate-tetrahydrofolate ligase, FTHFS, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — has part(s) (P527): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): NP_001229696. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): NP_001229697. Q20641742. Retrieved 2020-05-30. wikidata.org.
[16] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): NP_001229698. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): NP_056255. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): XP_005266964. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): XP_005266968. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): XP_011534031. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): XP_011534032. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): XP_011534033. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): XP_011534034. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): XP_011534035. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): XP_011534036. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — RefSeq protein ID (P637): XP_011534039. Q20641742. Retrieved 2020-05-30. wikidata.org.

Class ancestry

[1] ↑ Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. Retrieved May 3, 2026, from https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like

MLA

“Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like.

BibTeX

@misc{4ortxyz_methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like}}, year = {2026}, url = {https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like — https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like · Last refreshed: May 3, 2026