Lymphotoxin A

mammalian protein found in Mus musculus
Protein protein Q21992448

Facts

9 properties
Instance of
protein
Part of
Tumour necrosis factor-like domain superfamily, lymphotoxin-alpha, membrane protein, Tumour necrosis factor domain, protein family, Tumour necrosis factor, conserved site, protein family[2][3][4][5][6]
Biological process
positive regulation of chronic inflammatory response to antigenic stimulus, response to hypoxia, response to nutrient, positive regulation of humoral immune response mediated by circulating immunoglobulin, positive regulation of interferon-gamma production, response to lipopolysaccharide, humoral immune response, immune response, positive regulation of cell population proliferation, cell population proliferation, inflammatory response, lymph node development, cellular process or phenomenon, defense response to Gram-positive bacterium, regulation of signaling receptor activity, positive regulation of apoptotic process, negative regulation of fibroblast proliferation, positive regulation of glial cell proliferation, signal transduction[16][17][18][19][20][21][22]
Encoded by
Lta
Found in taxon
house mouse
Has part(s)
Tumour necrosis factor, conserved site, Tumour necrosis factor domain[7][8]
Imported from
wholeness_audit_2026-05-02
Molecular function
cytokine activity, protein binding, tumor necrosis factor receptor binding[9][10][11]
🏷️ Also known as
en Lta en Lymphotoxin A en lymphotoxin-alpha en TNF beta en TNF-beta en tumor necrosis factor ligand 1e en tumor necrosis factor ligand superfamily member 1
🔖 Identifiers · 3
Ensembl protein ID
ENSMUSP00000025266
RefSeq protein ID
NP_034865, XP_006523794
UniProt protein ID
P09225

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Summary

Lymphotoxin An is a protein[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] ↑ . wikidata.org.
  4. [5] ↑ . wikidata.org.
  5. [6] ↑ . wikidata.org.
  6. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . TNF/lymphotoxin-alpha double-mutant mice resist septic arthritis but display increased mortality in response to Staphylococcus aureus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . TNF/lymphotoxin-alpha double-mutant mice resist septic arthritis but display increased mortality in response to Staphylococcus aureus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . TNF/lymphotoxin-alpha double-mutant mice resist septic arthritis but display increased mortality in response to Staphylococcus aureus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] ↑ . Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Lymphotoxin A. Retrieved May 3, 2026, from https://4ort.xyz/entity/lymphotoxin-a
MLA “Lymphotoxin A.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/lymphotoxin-a.
BibTeX @misc{4ortxyz_lymphotoxin-a_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Lymphotoxin A}}, year = {2026}, url = {https://4ort.xyz/entity/lymphotoxin-a}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Lymphotoxin A — https://4ort.xyz/entity/lymphotoxin-a (retrieved 2026-05-03)

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