Leucine-rich repeat-containing G protein-coupled receptor 4

mammalian protein found in Mus musculus

Protein protein Q21984626

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Leucine-rich repeat-containing G protein-coupled receptor 4

Summary

Leucine-rich repeat-containing G protein-coupled receptor 4 is a protein^[1].

Key Facts

Leucine-rich repeat-containing G protein-coupled receptor 4's instance of is recorded as protein^[2].
Leucine-rich repeat-containing G protein-coupled receptor 4's UniProt protein ID is recorded as A2ARI4^[3].
Leucine-rich repeat-containing G protein-coupled receptor 4's part of is recorded as Leucine-rich repeat domain superfamily^[4].
Leucine-rich repeat-containing G protein-coupled receptor 4's part of is recorded as glycoprotein hormone receptor family^[5].
Leucine-rich repeat-containing G protein-coupled receptor 4's part of is recorded as membrane protein^[6].
Leucine-rich repeat-containing G protein-coupled receptor 4's part of is recorded as Leucine-rich repeat N-terminal domain, protein family^[7].
Leucine-rich repeat-containing G protein-coupled receptor 4's part of is recorded as GPCR, rhodopsin-like, 7TM, protein family^[8].
Leucine-rich repeat-containing G protein-coupled receptor 4's part of is recorded as Leucine-rich repeat, typical subtype, protein family^[9].
Leucine-rich repeat-containing G protein-coupled receptor 4's part of is recorded as Leucine-rich repeat, protein family^[10].
Leucine-rich repeat-containing G protein-coupled receptor 4's has part is recorded as Leucine-rich repeat^[11].
Leucine-rich repeat-containing G protein-coupled receptor 4's has part is recorded as leucine-rich repeat, typical subtype^[12].
Leucine-rich repeat-containing G protein-coupled receptor 4's has part is recorded as GPCR, rhodopsin-like, 7TM^[13].
Leucine-rich repeat-containing G protein-coupled receptor 4's has part is recorded as leucine-rich repeat N-terminal domain^[14].
Leucine-rich repeat-containing G protein-coupled receptor 4's RefSeq protein ID is recorded as NP_766259^[15].
Leucine-rich repeat-containing G protein-coupled receptor 4's RefSeq protein ID is recorded as XP_036013142^[16].
Leucine-rich repeat-containing G protein-coupled receptor 4's molecular function is recorded as G protein-coupled receptor activity^[17].
Leucine-rich repeat-containing G protein-coupled receptor 4's molecular function is recorded as signal transducer activity^[18].
Leucine-rich repeat-containing G protein-coupled receptor 4's molecular function is recorded as protein binding^[19].
Leucine-rich repeat-containing G protein-coupled receptor 4's molecular function is recorded as transmembrane signaling receptor activity^[20].
Leucine-rich repeat-containing G protein-coupled receptor 4's molecular function is recorded as protein-hormone receptor activity^[21].
Leucine-rich repeat-containing G protein-coupled receptor 4's molecular function is recorded as heparin binding^[22].
Leucine-rich repeat-containing G protein-coupled receptor 4's molecular function is recorded as Roundabout binding^[23].
Leucine-rich repeat-containing G protein-coupled receptor 4's cell component is recorded as integral component of membrane^[24].
Leucine-rich repeat-containing G protein-coupled receptor 4's cell component is recorded as membrane^[25].
Leucine-rich repeat-containing G protein-coupled receptor 4's cell component is recorded as plasma membrane^[26].

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Quick Facts

Instance of protein

Part of Leucine-rich repeat domain superfamily, glycoprotein hormone receptor family, membrane protein, Leucine-rich repeat N-terminal domain, protein family, GPCR, rhodopsin-like, 7TM, protein family, Leucine-rich repeat, typical subtype, protein family, Leucine-rich repeat, protein family

Properties

Biological process hair follicle development, G protein-coupled receptor signaling pathway, bone mineralization, cell differentiation, positive regulation of branching involved in ureteric bud morphogenesis, male genitalia development, metanephric nephron tubule morphogenesis, rhythmic process, immune system process, metanephric glomerulus development, positive regulation of canonical Wnt signaling pathway, epithelial cell proliferation, Wnt signaling pathway, tube morphogenesis, circadian regulation of gene expression, multicellular organism development, positive regulation of transcription, DNA-templated, cell differentiation involved in metanephros development, intestinal stem cell homeostasis, negative regulation of toll-like receptor signaling pathway, epithelial cell proliferation involved in renal tubule morphogenesis, bone remodeling, circadian rhythm, osteoblast differentiation, spermatogenesis, canonical Wnt signaling pathway involved in metanephric kidney development, digestive tract development, innate immune response, negative regulation of transcription, DNA-templated, signal transduction, negative regulation of cold-induced thermogenesis, axon guidance, negative chemotaxis

Cell component integral component of membrane, membrane, plasma membrane, integral component of plasma membrane, extracellular space

Encoded by Lgr4

Found in taxon house mouse

Has part(s) Leucine-rich repeat, leucine-rich repeat, typical subtype, GPCR, rhodopsin-like, 7TM, leucine-rich repeat N-terminal domain

Imported from wholeness_audit_2026-05-02

Molecular function G protein-coupled receptor activity, signal transducer activity, protein binding, transmembrane signaling receptor activity, protein-hormone receptor activity, heparin binding, Roundabout binding

External References (3)

Ensembl protein id ENSMUSP00000047325, ENSMUSP00000106666

Refseq protein id NP_766259, XP_036013142

Uniprot protein id A2ARI4

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — UniProt protein ID (P352): A2ARI4. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — part of (P361): Leucine-rich repeat domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — part of (P361): glycoprotein hormone receptor family. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — part of (P361): membrane protein. wikidata.org.
[7] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — part of (P361): Leucine-rich repeat N-terminal domain, protein family. wikidata.org.
[8] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — part of (P361): GPCR, rhodopsin-like, 7TM, protein family. wikidata.org.
[9] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — part of (P361): Leucine-rich repeat, typical subtype, protein family. wikidata.org.
[10] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — part of (P361): Leucine-rich repeat, protein family. wikidata.org.
[11] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — has part(s) (P527): Leucine-rich repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — has part(s) (P527): leucine-rich repeat, typical subtype. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — has part(s) (P527): GPCR, rhodopsin-like, 7TM. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — has part(s) (P527): leucine-rich repeat N-terminal domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — RefSeq protein ID (P637): NP_766259. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — RefSeq protein ID (P637): XP_036013142. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — molecular function (P680): G protein-coupled receptor activity. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — molecular function (P680): signal transducer activity. GOA. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — molecular function (P680): protein binding. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — molecular function (P680): transmembrane signaling receptor activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — molecular function (P680): protein-hormone receptor activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — molecular function (P680): heparin binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — molecular function (P680): Roundabout binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — cell component (P681): integral component of membrane. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — cell component (P681): membrane. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 — cell component (P681): plasma membrane. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Leucine-rich repeat-containing G protein-coupled receptor 4 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

“Leucine-rich repeat-containing G protein-coupled receptor 4.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/leucine-rich-repeat-containing-g-protein-coupled-receptor-4-q21984626.

BibTeX

@misc{4ortxyz_leucine-rich-repeat-containing-g-protein-coupled-receptor-4-q21984626_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Leucine-rich repeat-containing G protein-coupled receptor 4}}, year = {2026}, url = {https://4ort.xyz/entity/leucine-rich-repeat-containing-g-protein-coupled-receptor-4-q21984626}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Leucine-rich repeat-containing G protein-coupled receptor 4 — https://4ort.xyz/entity/leucine-rich-repeat-containing-g-protein-coupled-receptor-4-q21984626 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/leucine-rich-repeat-containing-g-protein-coupled-receptor-4-q21984626 · Last refreshed: May 3, 2026