Klotho

mammalian protein found in Homo sapiens
Protein protein Q414050
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Klotho

Summary

Klotho is a protein[1]. Klotho draws 103 Wikipedia views per month (protein category, ranking #105 of 987).[2]

Key Facts

  • Klotho's instance of is recorded as protein[3].
  • Klotho's subclass of is recorded as membrane protein[4].
  • Klotho's UniProt protein ID is recorded as Q9UEF7[5].
  • Klotho's part of is recorded as Klotho[6].
  • Klotho's part of is recorded as glycoside hydrolase superfamily[7].
  • Klotho's part of is recorded as auxiliary protein involved in transmembrane transport[8].
  • Klotho's part of is recorded as Glycosyl hydrolases family 1, N-terminal conserved site, protein family[9].
  • Klotho's has part is recorded as Glycosyl hydrolases family 1, N-terminal conserved site[10].
  • Klotho's RefSeq protein ID is recorded as NP_004786[11].
  • Klotho's RefSeq protein ID is recorded as XP_006719958[12].
  • Klotho's Freebase ID is recorded as /m/07lwt9[13].
  • Klotho's molecular function is recorded as hydrolase activity, hydrolyzing O-glycosyl compounds[14].
  • Klotho's molecular function is recorded as hormone activity[15].
  • Klotho's molecular function is recorded as beta-glucuronidase activity[16].
  • Klotho's molecular function is recorded as signal transducer activity[17].
  • Klotho's molecular function is recorded as hydrolase activity, acting on glycosyl bonds[18].
  • Klotho's molecular function is recorded as vitamin D binding[19].
  • Klotho's molecular function is recorded as fibroblast growth factor binding[20].
  • Klotho's molecular function is recorded as beta-glucosidase activity[21].
  • Klotho's molecular function is recorded as hydrolase activity[22].
  • Klotho's molecular function is recorded as phosphatidylinositol-4,5-bisphosphate 3-kinase activity[23].
  • Klotho's molecular function is recorded as fibroblast growth factor receptor binding[24].
  • Klotho's molecular function is recorded as 1-phosphatidylinositol-3-kinase activity[25].
  • Klotho's molecular function is recorded as beta-glucosidase activity[26].
  • Klotho's molecular function is recorded as fibroblast growth factor binding[27].

Why It Matters

Klotho draws 103 Wikipedia views per month (protein category, ranking #105 of 987).[2] Klotho has Wikipedia articles in 11 language editions, a strong signal of global cultural recognition.[28] Klotho is known by 7 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . wikidata.org.
  3. [5] . Q905695. Retrieved . wikidata.org.
  4. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] . Retrieved . wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [11] . Q20641742. Retrieved . wikidata.org.
  10. [12] . Q20641742. Retrieved . wikidata.org.
  11. [13] . Freebase Data Dumps. wikidata.org.
  12. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Klotho. Retrieved May 3, 2026, from https://4ort.xyz/entity/klotho
MLA “Klotho.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/klotho.
BibTeX @misc{4ortxyz_klotho_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Klotho}}, year = {2026}, url = {https://4ort.xyz/entity/klotho}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Klotho — https://4ort.xyz/entity/klotho (retrieved 2026-05-03)

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