Interleukin 11

mammalian protein found in Homo sapiens
Protein protein Q2698453
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Interleukin 11

Summary

Interleukin 11 is a protein[1].

Key Facts

  • Interleukin 11's instance of is recorded as protein[2].
  • Interleukin 11's physically interacts with is recorded as Interleukin 11 receptor subunit alpha[3].
  • Interleukin 11's UniProt protein ID is recorded as P20809[4].
  • Interleukin 11's part of is recorded as Interleukin-11, mammalian[5].
  • Interleukin 11's part of is recorded as four-helical cytokine-like, core[6].
  • Interleukin 11's Commons category is recorded as Interleukin-11[7].
  • Interleukin 11's RefSeq protein ID is recorded as NP_000632[8].
  • Interleukin 11's RefSeq protein ID is recorded as NP_001254647[9].
  • Interleukin 11's PDB structure ID is recorded as 4MHL[10].
  • Interleukin 11's Freebase ID is recorded as /m/0gtnsy[11].
  • Interleukin 11's molecular function is recorded as growth factor activity[12].
  • Interleukin 11's molecular function is recorded as interleukin-11 receptor binding[13].
  • Interleukin 11's molecular function is recorded as cytokine activity[14].
  • Interleukin 11's molecular function is recorded as protein binding[15].
  • Interleukin 11's molecular function is recorded as growth factor activity[16].
  • Interleukin 11's cell component is recorded as cytoplasm[17].
  • Interleukin 11's cell component is recorded as extracellular space[18].
  • Interleukin 11's cell component is recorded as extracellular region[19].
  • Interleukin 11's biological process is recorded as negative regulation of endothelial cell apoptotic process[20].
  • Interleukin 11's biological process is recorded as positive regulation of MAPK cascade[21].
  • Interleukin 11's biological process is recorded as positive regulation of peptidyl-serine phosphorylation[22].
  • Interleukin 11's biological process is recorded as B cell differentiation[23].
  • Interleukin 11's biological process is recorded as positive regulation of transcription by RNA polymerase II[24].
  • Interleukin 11's biological process is recorded as negative regulation of hormone secretion[25].
  • Interleukin 11's biological process is recorded as positive regulation of peptidyl-tyrosine phosphorylation[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . wikidata.org.
  3. [4] . Q905695. Retrieved . wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . wikidata.org.
  7. [8] . Q20641742. Retrieved . wikidata.org.
  8. [9] . Q20641742. Retrieved . wikidata.org.
  9. [10] . Q905695. Retrieved . wikidata.org.
  10. [11] . Freebase Data Dumps. wikidata.org.
  11. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . A proteome-scale map of the human interactome network. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . IL-4 and IL-13 induce protection of porcine endothelial cells from killing by human complement and from apoptosis through activation of a phosphatidylinositide 3-kinase/Akt pathway. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Inhibition of growth hormone-releasing factor production in mouse placenta by cytokines using gp130 as a signal transducer. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Interleukin 11. Retrieved May 3, 2026, from https://4ort.xyz/entity/interleukin-11
MLA “Interleukin 11.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/interleukin-11.
BibTeX @misc{4ortxyz_interleukin-11_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Interleukin 11}}, year = {2026}, url = {https://4ort.xyz/entity/interleukin-11}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Interleukin 11 — https://4ort.xyz/entity/interleukin-11 (retrieved 2026-05-03)

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