IL2-inducible T-cell kinase

mammalian protein found in Rattus norvegicus

Protein protein Q29526760

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IL2-inducible T-cell kinase

Summary

IL2-inducible T-cell kinase is a protein^[1].

Key Facts

IL2-inducible T-cell kinase's instance of is recorded as protein^[2].
IL2-inducible T-cell kinase's UniProt protein ID is recorded as D4A7W7^[3].
IL2-inducible T-cell kinase's part of is recorded as SH3-like domain superfamily^[4].
IL2-inducible T-cell kinase's part of is recorded as Protein kinase-like domain superfamily^[5].
IL2-inducible T-cell kinase's part of is recorded as PH-like domain superfamily^[6].
IL2-inducible T-cell kinase's part of is recorded as SH2 domain superfamily^[7].
IL2-inducible T-cell kinase's part of is recorded as Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family^[8].
IL2-inducible T-cell kinase's part of is recorded as pleckstrin homology domain, protein family^[9].
IL2-inducible T-cell kinase's part of is recorded as SH2 domain, protein family^[10].
IL2-inducible T-cell kinase's part of is recorded as SH3 domain, protein family^[11].
IL2-inducible T-cell kinase's part of is recorded as Protein kinase domain, protein family^[12].
IL2-inducible T-cell kinase's part of is recorded as Protein kinase, ATP binding site, protein family^[13].
IL2-inducible T-cell kinase's part of is recorded as Tyrosine-protein kinase, catalytic domain, protein family^[14].
IL2-inducible T-cell kinase's part of is recorded as Tyrosine-protein kinase, active site, protein family^[15].
IL2-inducible T-cell kinase's part of is recorded as Tyrosine-protein kinase ITK, SH3 domain, protein family^[16].
IL2-inducible T-cell kinase's part of is recorded as Zinc finger, Btk motif, protein family^[17].
IL2-inducible T-cell kinase's has part is recorded as SH3 domain^[18].
IL2-inducible T-cell kinase's has part is recorded as pleckstrin homology domain^[19].
IL2-inducible T-cell kinase's has part is recorded as protein kinase, ATP binding site^[20].
IL2-inducible T-cell kinase's has part is recorded as serine-threonine/tyrosine-protein kinase, catalytic domain^[21].
IL2-inducible T-cell kinase's has part is recorded as tyrosine-protein kinase, catalytic domain^[22].
IL2-inducible T-cell kinase's has part is recorded as protein kinase domain^[23].
IL2-inducible T-cell kinase's has part is recorded as tyrosine-protein kinase, active site^[24].
IL2-inducible T-cell kinase's has part is recorded as Zinc finger, Btk motif^[25].
IL2-inducible T-cell kinase's has part is recorded as SH2 domain^[26].

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Quick Facts

Instance of protein

Part of SH3-like domain superfamily, Protein kinase-like domain superfamily, PH-like domain superfamily, SH2 domain superfamily, Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family, pleckstrin homology domain, protein family, SH2 domain, protein family, SH3 domain, protein family, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family, Tyrosine-protein kinase, catalytic domain, protein family, Tyrosine-protein kinase, active site, protein family, Tyrosine-protein kinase ITK, SH3 domain, protein family, Zinc finger, Btk motif, protein family

Properties

Biological process cytokine production, NK T cell differentiation, adaptive immune response, protein phosphorylation, transmembrane receptor protein tyrosine kinase signaling pathway, activation of phospholipase C activity, phosphorylation, interleukin-4 production, intracellular signal transduction, peptidyl-tyrosine autophosphorylation, regulation of cell population proliferation, innate immune response, T cell receptor signaling pathway, adaptive immune response, T cell receptor signaling pathway, B cell receptor signaling pathway

Cell component cell-cell junction, extrinsic component of cytoplasmic side of plasma membrane, nucleus

Encoded by Itk

Found in taxon brown rat

Has part(s) SH3 domain, pleckstrin homology domain, protein kinase, ATP binding site, serine-threonine/tyrosine-protein kinase, catalytic domain, tyrosine-protein kinase, catalytic domain, protein kinase domain, tyrosine-protein kinase, active site, Zinc finger, Btk motif, SH2 domain, Tyrosine-protein kinase ITK, SH3 domain

Imported from wholeness_audit_2026-05-02

Molecular function nucleotide binding, protein kinase activity, protein tyrosine kinase activity, non-membrane spanning protein tyrosine kinase activity, signaling receptor binding, ATP binding, kinase activity, transferase activity

External References (3)

Ensembl protein id ENSRNOP00000009211

Refseq protein id NP_001102295, XP_017452909

Uniprot protein id D4A7W7

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ IL2-inducible T-cell kinase — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ IL2-inducible T-cell kinase — UniProt protein ID (P352): D4A7W7. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ IL2-inducible T-cell kinase — part of (P361): SH3-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ IL2-inducible T-cell kinase — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ IL2-inducible T-cell kinase — part of (P361): PH-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ IL2-inducible T-cell kinase — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ IL2-inducible T-cell kinase — part of (P361): Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[9] ↑ IL2-inducible T-cell kinase — part of (P361): pleckstrin homology domain, protein family. wikidata.org.
[10] ↑ IL2-inducible T-cell kinase — part of (P361): SH2 domain, protein family. wikidata.org.
[11] ↑ IL2-inducible T-cell kinase — part of (P361): SH3 domain, protein family. wikidata.org.
[12] ↑ IL2-inducible T-cell kinase — part of (P361): Protein kinase domain, protein family. wikidata.org.
[13] ↑ IL2-inducible T-cell kinase — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[14] ↑ IL2-inducible T-cell kinase — part of (P361): Tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[15] ↑ IL2-inducible T-cell kinase — part of (P361): Tyrosine-protein kinase, active site, protein family. wikidata.org.
[16] ↑ IL2-inducible T-cell kinase — part of (P361): Tyrosine-protein kinase ITK, SH3 domain, protein family. wikidata.org.
[17] ↑ IL2-inducible T-cell kinase — part of (P361): Zinc finger, Btk motif, protein family. wikidata.org.
[18] ↑ IL2-inducible T-cell kinase — has part(s) (P527): SH3 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ IL2-inducible T-cell kinase — has part(s) (P527): pleckstrin homology domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ IL2-inducible T-cell kinase — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ IL2-inducible T-cell kinase — has part(s) (P527): serine-threonine/tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ IL2-inducible T-cell kinase — has part(s) (P527): tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ IL2-inducible T-cell kinase — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ IL2-inducible T-cell kinase — has part(s) (P527): tyrosine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ IL2-inducible T-cell kinase — has part(s) (P527): Zinc finger, Btk motif. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ IL2-inducible T-cell kinase — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ IL2-inducible T-cell kinase is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). IL2-inducible T-cell kinase. Retrieved May 3, 2026, from https://4ort.xyz/entity/il2-inducible-t-cell-kinase-q29526760

MLA

“IL2-inducible T-cell kinase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/il2-inducible-t-cell-kinase-q29526760.

BibTeX

@misc{4ortxyz_il2-inducible-t-cell-kinase-q29526760_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{IL2-inducible T-cell kinase}}, year = {2026}, url = {https://4ort.xyz/entity/il2-inducible-t-cell-kinase-q29526760}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): IL2-inducible T-cell kinase — https://4ort.xyz/entity/il2-inducible-t-cell-kinase-q29526760 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/il2-inducible-t-cell-kinase-q29526760 · Last refreshed: May 3, 2026