Huntingtin interacting protein 1 related

mammalian protein found in Mus musculus

Protein protein Q21495850

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Huntingtin interacting protein 1 related

Summary

Huntingtin interacting protein 1 related is a protein^[1].

Key Facts

Huntingtin interacting protein 1 related's instance of is recorded as protein^[2].
Huntingtin interacting protein 1 related's UniProt protein ID is recorded as Q9JKY5^[3].
Huntingtin interacting protein 1 related's part of is recorded as ENTH/VHS^[4].
Huntingtin interacting protein 1 related's part of is recorded as Huntingtin-interacting protein 1-related protein^[5].
Huntingtin interacting protein 1 related's part of is recorded as I/LWEQ domain superfamily^[6].
Huntingtin interacting protein 1 related's part of is recorded as membrane protein^[7].
Huntingtin interacting protein 1 related's part of is recorded as I/LWEQ domain, protein family^[8].
Huntingtin interacting protein 1 related's part of is recorded as Huntingtin-interacting protein 1, clathrin-binding domain, protein family^[9].
Huntingtin interacting protein 1 related's part of is recorded as AP180 N-terminal homology (ANTH) domain, protein family^[10].
Huntingtin interacting protein 1 related's part of is recorded as ENTH domain, protein family^[11].
Huntingtin interacting protein 1 related's has part is recorded as ENTH domain^[12].
Huntingtin interacting protein 1 related's has part is recorded as Huntingtin-interacting protein 1, clathrin-binding domain^[13].
Huntingtin interacting protein 1 related's has part is recorded as I/LWEQ domain^[14].
Huntingtin interacting protein 1 related's has part is recorded as AP180 N-terminal homology (ANTH) domain^[15].
Huntingtin interacting protein 1 related's RefSeq protein ID is recorded as NP_659507^[16].
Huntingtin interacting protein 1 related's RefSeq protein ID is recorded as XP_006530432^[17].
Huntingtin interacting protein 1 related's RefSeq protein ID is recorded as XP_006530433^[18].
Huntingtin interacting protein 1 related's molecular function is recorded as actin binding^[19].
Huntingtin interacting protein 1 related's molecular function is recorded as phospholipid binding^[20].
Huntingtin interacting protein 1 related's molecular function is recorded as phosphatidylinositol binding^[21].
Huntingtin interacting protein 1 related's molecular function is recorded as protein binding^[22].
Huntingtin interacting protein 1 related's molecular function is recorded as phosphatidylinositol-4,5-bisphosphate binding^[23].
Huntingtin interacting protein 1 related's molecular function is recorded as phosphatidylinositol-3,4,5-trisphosphate binding^[24].
Huntingtin interacting protein 1 related's molecular function is recorded as SH3 domain binding^[25].
Huntingtin interacting protein 1 related's molecular function is recorded as clathrin binding^[26].

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Quick Facts

Instance of protein

Part of ENTH/VHS, Huntingtin-interacting protein 1-related protein, I/LWEQ domain superfamily, membrane protein, I/LWEQ domain, protein family, Huntingtin-interacting protein 1, clathrin-binding domain, protein family, AP180 N-terminal homology (ANTH) domain, protein family, ENTH domain, protein family

Properties

Biological process endocytosis, receptor-mediated endocytosis, apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process, regulation of endocytosis, negative regulation of actin filament polymerization, positive regulation of protein binding, regulation of actin cytoskeleton organization, negative regulation of Arp2/3 complex-mediated actin nucleation, positive regulation of apoptotic process, negative regulation of apoptotic process, positive regulation of epidermal growth factor receptor signaling pathway, clathrin coat assembly, protein stabilization, digestive system development, regulation of gastric acid secretion, membrane organization, positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway, positive regulation of clathrin coat assembly, positive regulation of clathrin-dependent endocytosis, positive regulation of platelet-derived growth factor receptor-beta signaling pathway, regulation of clathrin-dependent endocytosis, activation of cysteine-type endopeptidase activity involved in apoptotic process, actin filament organization, positive regulation of receptor-mediated endocytosis, clathrin coat assembly

Cell component clathrin-coated pit, cytoskeleton, cytoplasmic vesicle, intracellular membrane-bounded organelle, endomembrane system, clathrin-coated vesicle membrane, mitochondrion, cell cortex, postsynaptic density, apical plasma membrane, clathrin-coated vesicle, ruffle membrane, dendrite cytoplasm, soma, dendritic spine, perinuclear region of cytoplasm, synaptic membrane, cytoplasm, cytosol, membrane, cytoplasm, AP-2 adaptor complex, clathrin-coated vesicle, actin cortical patch, intracellular membrane-bounded organelle

Encoded by Hip1r

Found in taxon house mouse

Has part(s) ENTH domain, Huntingtin-interacting protein 1, clathrin-binding domain, I/LWEQ domain, AP180 N-terminal homology (ANTH) domain

Imported from wholeness_audit_2026-05-02

Molecular function actin binding, phospholipid binding, phosphatidylinositol binding, protein binding, phosphatidylinositol-4,5-bisphosphate binding, phosphatidylinositol-3,4,5-trisphosphate binding, SH3 domain binding, clathrin binding, clathrin light chain binding, clathrin adaptor activity, protein homodimerization activity, phosphatidylinositol-3,4-bisphosphate binding, protein heterodimerization activity, actin filament binding, phosphatidylinositol-3,5-bisphosphate binding, identical protein binding, clathrin binding, clathrin light chain binding, phosphatidylinositol binding, clathrin adaptor activity, phosphatidylinositol-3,4-bisphosphate binding, actin filament binding, phosphatidylinositol-3,5-bisphosphate binding

External References (3)

Ensembl protein id ENSMUSP00000000939, ENSMUSP00000127361, ENSMUSP00000130766, ENSMUSP00000143309

Refseq protein id NP_659507, XP_006530432, XP_006530433

Uniprot protein id Q9JKY5

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Huntingtin interacting protein 1 related — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Huntingtin interacting protein 1 related — UniProt protein ID (P352): Q9JKY5. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ Huntingtin interacting protein 1 related — part of (P361): ENTH/VHS. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Huntingtin interacting protein 1 related — part of (P361): Huntingtin-interacting protein 1-related protein. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Huntingtin interacting protein 1 related — part of (P361): I/LWEQ domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Huntingtin interacting protein 1 related — part of (P361): membrane protein. wikidata.org.
[8] ↑ Huntingtin interacting protein 1 related — part of (P361): I/LWEQ domain, protein family. wikidata.org.
[9] ↑ Huntingtin interacting protein 1 related — part of (P361): Huntingtin-interacting protein 1, clathrin-binding domain, protein family. wikidata.org.
[10] ↑ Huntingtin interacting protein 1 related — part of (P361): AP180 N-terminal homology (ANTH) domain, protein family. wikidata.org.
[11] ↑ Huntingtin interacting protein 1 related — part of (P361): ENTH domain, protein family. wikidata.org.
[12] ↑ Huntingtin interacting protein 1 related — has part(s) (P527): ENTH domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Huntingtin interacting protein 1 related — has part(s) (P527): Huntingtin-interacting protein 1, clathrin-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Huntingtin interacting protein 1 related — has part(s) (P527): I/LWEQ domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Huntingtin interacting protein 1 related — has part(s) (P527): AP180 N-terminal homology (ANTH) domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Huntingtin interacting protein 1 related — RefSeq protein ID (P637): NP_659507. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ Huntingtin interacting protein 1 related — RefSeq protein ID (P637): XP_006530432. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ Huntingtin interacting protein 1 related — RefSeq protein ID (P637): XP_006530433. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ Huntingtin interacting protein 1 related — molecular function (P680): actin binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Huntingtin interacting protein 1 related — molecular function (P680): phospholipid binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Huntingtin interacting protein 1 related — molecular function (P680): phosphatidylinositol binding. GOA. Retrieved 2018-06-05. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Huntingtin interacting protein 1 related — molecular function (P680): protein binding. A Hip1R-cortactin complex negatively regulates actin assembly associated with endocytosis. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Huntingtin interacting protein 1 related — molecular function (P680): phosphatidylinositol-4,5-bisphosphate binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Huntingtin interacting protein 1 related — molecular function (P680): phosphatidylinositol-3,4,5-trisphosphate binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Huntingtin interacting protein 1 related — molecular function (P680): SH3 domain binding. A Hip1R-cortactin complex negatively regulates actin assembly associated with endocytosis. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Huntingtin interacting protein 1 related — molecular function (P680): clathrin binding. GOA. Retrieved 2018-06-05. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Huntingtin interacting protein 1 related is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Huntingtin interacting protein 1 related. Retrieved May 3, 2026, from https://4ort.xyz/entity/huntingtin-interacting-protein-1-related-q21495850

MLA

“Huntingtin interacting protein 1 related.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/huntingtin-interacting-protein-1-related-q21495850.

BibTeX

@misc{4ortxyz_huntingtin-interacting-protein-1-related-q21495850_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Huntingtin interacting protein 1 related}}, year = {2026}, url = {https://4ort.xyz/entity/huntingtin-interacting-protein-1-related-q21495850}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Huntingtin interacting protein 1 related — https://4ort.xyz/entity/huntingtin-interacting-protein-1-related-q21495850 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/huntingtin-interacting-protein-1-related-q21495850 · Last refreshed: May 3, 2026