haptoglobin

mammalian protein found in Homo sapiens
Protein protein Q422025
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Summary

haptoglobin is a protein[1]. haptoglobin ranks in the top 8% of protein entities by monthly Wikipedia readership (311 views/month).[2]

Key Facts

  • haptoglobin's instance of is recorded as protein[3].
  • haptoglobin is part of Peptidase S1, PA clan[4].
  • haptoglobin is part of Sushi/SCR/CCP superfamily[5].
  • haptoglobin is part of haptoglobin[6].
  • haptoglobin is part of Sushi/SCR/CCP domain, protein family[7].
  • haptoglobin is part of Serine proteases, trypsin domain, protein family[8].
  • haptoglobin comprises serine proteases, trypsin domain[9].
  • haptoglobin comprises sushi/SCR/CCP domain[10].
  • haptoglobin's molecular function is recorded as antioxidant activity[11].
  • haptoglobin's molecular function is recorded as protein binding[12].
  • haptoglobin's molecular function is recorded as hemoglobin binding[13].
  • haptoglobin's molecular function is recorded as serine-type endopeptidase activity[14].
  • haptoglobin's cell component is recorded as extracellular region[15].
  • haptoglobin's cell component is recorded as endocytic vesicle lumen[16].
  • haptoglobin's cell component is recorded as extracellular exosome[17].
  • haptoglobin's cell component is recorded as blood microparticle[18].
  • haptoglobin's cell component is recorded as haptoglobin-hemoglobin complex[19].
  • haptoglobin's cell component is recorded as extracellular space[20].
  • haptoglobin's cell component is recorded as specific granule lumen[21].
  • haptoglobin's cell component is recorded as tertiary granule lumen[22].
  • haptoglobin's cell component is recorded as extracellular space[23].
  • haptoglobin's cell component is recorded as extracellular exosome[24].
  • haptoglobin's cell component is recorded as blood microparticle[25].
  • haptoglobin's biological process is recorded as cellular oxidant detoxification[26].
  • haptoglobin's biological process is recorded as defense response[27].

Why It Matters

haptoglobin ranks in the top 8% of protein entities by monthly Wikipedia readership (311 views/month).[2] haptoglobin has Wikipedia articles in 17 language editions, a strong signal of global cultural recognition.[28] haptoglobin is known by 9 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . UniProt. Retrieved . wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . Haptoglobin binds the antiatherogenic protein apolipoprotein E - impairment of apolipoprotein E stimulation of both lecithin:cholesterol acyltransferase activity and cholesterol uptake by hepatocytes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . Peroxidase activity of hemoglobin-haptoglobin complexes: covalent aggregation and oxidative stress in plasma and macrophages. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . Innate immunity proteins and a new truncated form of SPLUNC1 in nasopharyngeal aspirates from infants with respiratory syncytial virus infection. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Human neutrophils secrete bioactive paucimannosidic proteins from azurophilic granules into pathogen-infected sputum. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . Large-scale proteomics and phosphoproteomics of urinary exosomes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . Haptoglobin: a natural bacteriostat. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] ↑ . Wikidata sitelinks. wikidata.org.
  3. [29] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). haptoglobin. Retrieved October 14, 2026, from https://4ort.xyz/entity/haptoglobin
MLA “haptoglobin.” 4ort.xyz Knowledge Graph, 4ort.xyz, 14 Oct. 2026, https://4ort.xyz/entity/haptoglobin.
BibTeX @misc{4ortxyz_haptoglobin_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{haptoglobin}}, year = {2026}, url = {https://4ort.xyz/entity/haptoglobin}, note = {Accessed: 2026-10-14}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): haptoglobin — https://4ort.xyz/entity/haptoglobin (retrieved 2026-10-14)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 20w ago · Twofivesixbot bot · 2026-05-25 view diff on Wikidata ↗
    Cell component → extracellular region, endocytic vesicle lumen, extracellular exosome +8
    Part of → —
    Instance of → —
    Part of → Peptidase S1, PA clan, Sushi/SCR/CCP superfamily, haptoglobin +2
    + 8 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-update-qualifiers:1||1|2 */ National library of israel j9u id: 987007550740205171, mv to monolingual text names on J9U statements"
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