GLI-Kruppel family member GLI2

mammalian protein found in Mus musculus

Protein protein Q14886550

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GLI-Kruppel family member GLI2

Summary

GLI-Kruppel family member GLI2 is a protein^[1].

Key Facts

GLI-Kruppel family member GLI2's instance of is recorded as protein^[2].
GLI-Kruppel family member GLI2's UniProt protein ID is recorded as Q0VGT2^[3].
GLI-Kruppel family member GLI2's part of is recorded as Zinc finger C2H2 superfamily^[4].
GLI-Kruppel family member GLI2's part of is recorded as membrane protein^[5].
GLI-Kruppel family member GLI2's part of is recorded as Zinc finger C2H2-type, protein family^[6].
GLI-Kruppel family member GLI2's has part is recorded as Zinc finger C2H2-type^[7].
GLI-Kruppel family member GLI2's RefSeq protein ID is recorded as NP_001074594^[8].
GLI-Kruppel family member GLI2's RefSeq protein ID is recorded as XP_006529204^[9].
GLI-Kruppel family member GLI2's RefSeq protein ID is recorded as XP_011246226^[10].
GLI-Kruppel family member GLI2's RefSeq protein ID is recorded as XP_030104138^[11].
GLI-Kruppel family member GLI2's RefSeq protein ID is recorded as XP_036016339^[12].
GLI-Kruppel family member GLI2's RefSeq protein ID is recorded as XP_036016357^[13].
GLI-Kruppel family member GLI2's RefSeq protein ID is recorded as XP_036016377^[14].
GLI-Kruppel family member GLI2's RefSeq protein ID is recorded as XP_036016415^[15].
GLI-Kruppel family member GLI2's molecular function is recorded as DNA-binding transcription factor activity^[16].
GLI-Kruppel family member GLI2's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[17].
GLI-Kruppel family member GLI2's molecular function is recorded as metal ion binding^[18].
GLI-Kruppel family member GLI2's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding^[19].
GLI-Kruppel family member GLI2's molecular function is recorded as zinc ion binding^[20].
GLI-Kruppel family member GLI2's molecular function is recorded as chromatin binding^[21].
GLI-Kruppel family member GLI2's molecular function is recorded as protein binding^[22].
GLI-Kruppel family member GLI2's molecular function is recorded as nucleic acid binding^[23].
GLI-Kruppel family member GLI2's molecular function is recorded as DNA binding^[24].
GLI-Kruppel family member GLI2's molecular function is recorded as sequence-specific DNA binding^[25].
GLI-Kruppel family member GLI2's molecular function is recorded as transcription factor binding^[26].

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Quick Facts

Instance of protein

Part of Zinc finger C2H2 superfamily, membrane protein, Zinc finger C2H2-type, protein family

Properties

Biological process pattern specification process, skeletal system development, smoothened signaling pathway involved in ventral spinal cord interneuron specification, notochord regression, anatomical structure formation involved in morphogenesis, hindgut morphogenesis, spinal cord dorsal/ventral patterning, mammary gland development, odontogenesis of dentin-containing tooth, prostatic bud formation, negative regulation of chondrocyte differentiation, cerebellar cortex morphogenesis, cell population proliferation, spinal cord ventral commissure morphogenesis, floor plate formation, regulation of transcription, DNA-templated, kidney development, lung development, tube development, response to mechanical stimulus, embryonic digit morphogenesis, head development, neuron development, in utero embryonic development, transcription, DNA-templated, mammary gland duct morphogenesis, morphogenesis of an epithelium, positive regulation of transcription, DNA-templated, ventral midline development, development of the heart, positive regulation of neuron differentiation, neural tube development, smoothened signaling pathway, spinal cord motor neuron differentiation, proximal/distal pattern formation, cell differentiation, chondrocyte differentiation, anatomical structure development, smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation, cellular response to organic cyclic compound, negative regulation of apoptotic process, negative regulation of transcription by RNA polymerase II, positive regulation of DNA replication, developmental growth, osteoblast development, dorsal/ventral neural tube patterning, dorsal/ventral pattern formation, branching morphogenesis of an epithelial tube, embryonic digestive tract development, pituitary gland development, hindbrain development, ventral spinal cord development, axon guidance, multicellular organism development, regulation of smoothened signaling pathway, smoothened signaling pathway involved in dorsal/ventral neural tube patterning, smoothened signaling pathway involved in spinal cord motor neuron cell fate specification, cochlea morphogenesis, positive regulation of cell population proliferation, anterior/posterior pattern specification, positive regulation of transcription by RNA polymerase II, transcription by RNA polymerase II, osteoblast differentiation, epidermal cell differentiation, cellular response to virus, prostate gland development, cell population proliferation

Cell component cytoplasm, cytosol, membrane, nuclear speck, axoneme, ciliary tip, nucleus, motile cilium, nucleolus, cilium, cell projection, nucleoplasm

Encoded by Gli2

Found in taxon house mouse

Has part(s) Zinc finger C2H2-type

Imported from wholeness_audit_2026-05-02

Molecular function DNA-binding transcription factor activity, DNA-binding transcription activator activity, RNA polymerase II-specific, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, zinc ion binding, chromatin binding, protein binding, nucleic acid binding, DNA binding, sequence-specific DNA binding, transcription factor binding, promoter-specific chromatin binding

External References (3)

Ensembl protein id ENSMUSP00000123808, ENSMUSP00000124132, ENSMUSP00000124768, ENSMUSP00000125059, ENSMUSP00000125342, ENSMUSP00000125634, ENSMUSP00000125661, ENSMUSP00000054837

Refseq protein id NP_001074594, XP_006529204, XP_011246226, XP_030104138, XP_036016339, XP_036016357, XP_036016377, XP_036016415

Uniprot protein id Q0VGT2

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ GLI-Kruppel family member GLI2 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ GLI-Kruppel family member GLI2 — UniProt protein ID (P352): Q0VGT2. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ GLI-Kruppel family member GLI2 — part of (P361): Zinc finger C2H2 superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ GLI-Kruppel family member GLI2 — part of (P361): membrane protein. wikidata.org.
[6] ↑ GLI-Kruppel family member GLI2 — part of (P361): Zinc finger C2H2-type, protein family. wikidata.org.
[7] ↑ GLI-Kruppel family member GLI2 — has part(s) (P527): Zinc finger C2H2-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ GLI-Kruppel family member GLI2 — RefSeq protein ID (P637): NP_001074594. Q20641742. Retrieved 2022-03-20. wikidata.org.
[9] ↑ GLI-Kruppel family member GLI2 — RefSeq protein ID (P637): XP_006529204. Q20641742. Retrieved 2022-03-20. wikidata.org.
[10] ↑ GLI-Kruppel family member GLI2 — RefSeq protein ID (P637): XP_011246226. Q20641742. Retrieved 2022-03-20. wikidata.org.
[11] ↑ GLI-Kruppel family member GLI2 — RefSeq protein ID (P637): XP_030104138. Q20641742. Retrieved 2022-03-20. wikidata.org.
[12] ↑ GLI-Kruppel family member GLI2 — RefSeq protein ID (P637): XP_036016339. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ GLI-Kruppel family member GLI2 — RefSeq protein ID (P637): XP_036016357. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ GLI-Kruppel family member GLI2 — RefSeq protein ID (P637): XP_036016377. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ GLI-Kruppel family member GLI2 — RefSeq protein ID (P637): XP_036016415. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ GLI-Kruppel family member GLI2 — molecular function (P680): DNA-binding transcription factor activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ GLI-Kruppel family member GLI2 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling. Retrieved 2018-06-05. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ GLI-Kruppel family member GLI2 — molecular function (P680): metal ion binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ GLI-Kruppel family member GLI2 — molecular function (P680): RNA polymerase II cis-regulatory region sequence-specific DNA binding. The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ GLI-Kruppel family member GLI2 — molecular function (P680): zinc ion binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ GLI-Kruppel family member GLI2 — molecular function (P680): chromatin binding. GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ GLI-Kruppel family member GLI2 — molecular function (P680): protein binding. Physical and functional interactions between Zic and Gli proteins. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ GLI-Kruppel family member GLI2 — molecular function (P680): nucleic acid binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ GLI-Kruppel family member GLI2 — molecular function (P680): DNA binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ GLI-Kruppel family member GLI2 — molecular function (P680): sequence-specific DNA binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ GLI-Kruppel family member GLI2 — molecular function (P680): transcription factor binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ GLI-Kruppel family member GLI2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). GLI-Kruppel family member GLI2. Retrieved May 3, 2026, from https://4ort.xyz/entity/gli-kruppel-family-member-gli2

MLA

“GLI-Kruppel family member GLI2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/gli-kruppel-family-member-gli2.

BibTeX

@misc{4ortxyz_gli-kruppel-family-member-gli2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{GLI-Kruppel family member GLI2}}, year = {2026}, url = {https://4ort.xyz/entity/gli-kruppel-family-member-gli2}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): GLI-Kruppel family member GLI2 — https://4ort.xyz/entity/gli-kruppel-family-member-gli2 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/gli-kruppel-family-member-gli2 · Last refreshed: May 3, 2026