F-box and WD-40 domain protein 7

mammalian protein found in Mus musculus

Protein protein Q21495706

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F-box and WD-40 domain protein 7

Summary

F-box and WD-40 domain protein 7 is a protein^[1].

Key Facts

F-box and WD-40 domain protein 7's instance of is recorded as protein^[2].
F-box and WD-40 domain protein 7's subclass of is recorded as protein^[3].
F-box and WD-40 domain protein 7's UniProt protein ID is recorded as Q8VBV4^[4].
F-box and WD-40 domain protein 7's part of is recorded as WD40/YVTN repeat-like-containing domain superfamily^[5].
F-box and WD-40 domain protein 7's part of is recorded as WD40-repeat-containing domain superfamily^[6].
F-box and WD-40 domain protein 7's part of is recorded as F-box-like domain superfamily^[7].
F-box and WD-40 domain protein 7's part of is recorded as F-box protein^[8].
F-box and WD-40 domain protein 7's part of is recorded as WD40 repeat, protein family^[9].
F-box and WD-40 domain protein 7's part of is recorded as WD40 repeat, conserved site, protein family^[10].
F-box and WD-40 domain protein 7's part of is recorded as G-protein beta WD-40 repeat, protein family^[11].
F-box and WD-40 domain protein 7's has part is recorded as WD40 repeat^[12].
F-box and WD-40 domain protein 7's has part is recorded as G-protein beta WD-40 repeat^[13].
F-box and WD-40 domain protein 7's has part is recorded as WD40 repeat, conserved site^[14].
F-box and WD-40 domain protein 7's has part is recorded as F-box domain^[15].
F-box and WD-40 domain protein 7's RefSeq protein ID is recorded as NP_001171244^[16].
F-box and WD-40 domain protein 7's RefSeq protein ID is recorded as NP_001171245^[17].
F-box and WD-40 domain protein 7's RefSeq protein ID is recorded as NP_536353^[18].
F-box and WD-40 domain protein 7's RefSeq protein ID is recorded as XP_006501719^[19].
F-box and WD-40 domain protein 7's RefSeq protein ID is recorded as XP_006501720^[20].
F-box and WD-40 domain protein 7's RefSeq protein ID is recorded as XP_006501721^[21].
F-box and WD-40 domain protein 7's molecular function is recorded as DNA-binding transcription factor activity^[22].
F-box and WD-40 domain protein 7's molecular function is recorded as protein binding^[23].
F-box and WD-40 domain protein 7's molecular function is recorded as ubiquitin-protein transferase activity^[24].
F-box and WD-40 domain protein 7's molecular function is recorded as cyclin binding^[25].
F-box and WD-40 domain protein 7's molecular function is recorded as protein-macromolecule adaptor activity^[26].

⭐ Popularity Graph

0/100 established

Quick Facts

Instance of protein

Subclass of protein

Part of WD40/YVTN repeat-like-containing domain superfamily, WD40-repeat-containing domain superfamily, F-box-like domain superfamily, F-box protein, WD40 repeat, protein family, WD40 repeat, conserved site, protein family, G-protein beta WD-40 repeat, protein family

Properties

Biological process Notch signaling pathway, lung development, vasculogenesis, negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding, protein destabilization, regulation of cell migration involved in sprouting angiogenesis, regulation of transcription, DNA-templated, cellular response to DNA damage stimulus, cellular response to UV, proteasome-mediated ubiquitin-dependent protein catabolic process, sister chromatid cohesion, protein ubiquitination, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination, negative regulation of DNA endoreduplication, positive regulation of epidermal growth factor-activated receptor activity, protein stabilization, positive regulation of ubiquitin-protein transferase activity, positive regulation of ERK1 and ERK2 cascade, positive regulation of proteasomal protein catabolic process, regulation of autophagy of mitochondrion, positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway, positive regulation of protein targeting to mitochondrion, positive regulation of ubiquitin-dependent protein catabolic process, negative regulation of osteoclast development, sister chromatid cohesion, negative regulation of gene expression, ubiquitin recycling, protein ubiquitination, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination, negative regulation of DNA endoreduplication, proteasome-mediated ubiquitin-dependent protein catabolic process, positive regulation of epidermal growth factor-activated receptor activity, protein stabilization, positive regulation of ubiquitin-protein transferase activity, positive regulation of ERK1 and ERK2 cascade, positive regulation of proteasomal protein catabolic process, regulation of autophagy of mitochondrion, positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway, positive regulation of protein targeting to mitochondrion, positive regulation of ubiquitin-dependent protein catabolic process, negative regulation of osteoclast development, negative regulation of gene expression, regulation of circadian rhythm, positive regulation of ubiquitin-dependent protein catabolic process, regulation of circadian rhythm, rhythmic process

Cell component integral component of membrane, Golgi apparatus, endoplasmic reticulum, mitochondrion, perinuclear region of cytoplasm, nucleus, nucleoplasm, nucleolus, cytoplasm, SCF ubiquitin ligase complex, protein-containing complex, Parkin-FBXW7-Cul1 ubiquitin ligase complex, cytosol, nucleus, cytoplasm, SCF ubiquitin ligase complex, Parkin-FBXW7-Cul1 ubiquitin ligase complex

Encoded by Fbxw7

Found in taxon house mouse

Has part(s) WD40 repeat, G-protein beta WD-40 repeat, WD40 repeat, conserved site, F-box domain

Imported from wholeness_audit_2026-05-02

Molecular function DNA-binding transcription factor activity, protein binding, ubiquitin-protein transferase activity, cyclin binding, protein-macromolecule adaptor activity, ubiquitin protein ligase binding, identical protein binding, phosphothreonine residue binding, ubiquitin-protein transferase activator activity, ubiquitin protein ligase activity, cyclin binding, protein-macromolecule adaptor activity, ubiquitin protein ligase binding, identical protein binding, ubiquitin binding, phosphothreonine residue binding, ubiquitin-protein transferase activator activity

External References (3)

Ensembl protein id ENSMUSP00000029727, ENSMUSP00000103302, ENSMUSP00000103305, ENSMUSP00000103306

Refseq protein id NP_001171244, NP_001171245, NP_536353, XP_006501719, XP_006501720, XP_006501721

Uniprot protein id Q8VBV4

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ F-box and WD-40 domain protein 7 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ F-box and WD-40 domain protein 7 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ F-box and WD-40 domain protein 7 — UniProt protein ID (P352): Q8VBV4. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ F-box and WD-40 domain protein 7 — part of (P361): WD40/YVTN repeat-like-containing domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ F-box and WD-40 domain protein 7 — part of (P361): WD40-repeat-containing domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ F-box and WD-40 domain protein 7 — part of (P361): F-box-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ F-box and WD-40 domain protein 7 — part of (P361): F-box protein. wikidata.org.
[9] ↑ F-box and WD-40 domain protein 7 — part of (P361): WD40 repeat, protein family. wikidata.org.
[10] ↑ F-box and WD-40 domain protein 7 — part of (P361): WD40 repeat, conserved site, protein family. wikidata.org.
[11] ↑ F-box and WD-40 domain protein 7 — part of (P361): G-protein beta WD-40 repeat, protein family. wikidata.org.
[12] ↑ F-box and WD-40 domain protein 7 — has part(s) (P527): WD40 repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ F-box and WD-40 domain protein 7 — has part(s) (P527): G-protein beta WD-40 repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ F-box and WD-40 domain protein 7 — has part(s) (P527): WD40 repeat, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ F-box and WD-40 domain protein 7 — has part(s) (P527): F-box domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ F-box and WD-40 domain protein 7 — RefSeq protein ID (P637): NP_001171244. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ F-box and WD-40 domain protein 7 — RefSeq protein ID (P637): NP_001171245. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ F-box and WD-40 domain protein 7 — RefSeq protein ID (P637): NP_536353. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ F-box and WD-40 domain protein 7 — RefSeq protein ID (P637): XP_006501719. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ F-box and WD-40 domain protein 7 — RefSeq protein ID (P637): XP_006501720. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ F-box and WD-40 domain protein 7 — RefSeq protein ID (P637): XP_006501721. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ F-box and WD-40 domain protein 7 — molecular function (P680): DNA-binding transcription factor activity. Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor. Retrieved 2018-06-21. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ F-box and WD-40 domain protein 7 — molecular function (P680): protein binding. The Fbw7 Tumor Suppressor Regulates Nuclear Factor E2-related Factor 1 Transcription Factor Turnover through Proteasome-mediated Proteolysis. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ F-box and WD-40 domain protein 7 — molecular function (P680): ubiquitin-protein transferase activity. GOA. Retrieved 2018-10-11. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ F-box and WD-40 domain protein 7 — molecular function (P680): cyclin binding. GOA. Retrieved 2018-06-21. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ F-box and WD-40 domain protein 7 — molecular function (P680): protein-macromolecule adaptor activity. GOA. Retrieved 2018-06-21. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ F-box and WD-40 domain protein 7 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). F-box and WD-40 domain protein 7. Retrieved May 3, 2026, from https://4ort.xyz/entity/f-box-and-wd-40-domain-protein-7

MLA

“F-box and WD-40 domain protein 7.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/f-box-and-wd-40-domain-protein-7.

BibTeX

@misc{4ortxyz_f-box-and-wd-40-domain-protein-7_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{F-box and WD-40 domain protein 7}}, year = {2026}, url = {https://4ort.xyz/entity/f-box-and-wd-40-domain-protein-7}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): F-box and WD-40 domain protein 7 — https://4ort.xyz/entity/f-box-and-wd-40-domain-protein-7 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/f-box-and-wd-40-domain-protein-7 · Last refreshed: May 3, 2026