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erythropoietin

mammalian protein found in Homo sapiens
Class type of: protein-coding gene Q218706
erythropoietin

Facts

11 properties
Instance of
gene
Subclass of
protein-coding gene
Part of
erythropoietin, four-helical cytokine-like, core, Erythropoietin/thrombopoeitin, conserved site, protein family[3][4][5]
Biological process
erythrocyte maturation, negative regulation of cation channel activity, response to interleukin-1, response to hypoxia, negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress, response to nutrient, response to salt stress, negative regulation of erythrocyte apoptotic process, response to testosterone, regulation of transcription by RNA polymerase II, response to hyperoxia, positive regulation of Ras protein signal transduction, ageing, negative regulation of apoptotic process, negative regulation of transcription by RNA polymerase II, response to electrical stimulus, blood circulation, response to estrogen, cellular hyperosmotic response, positive regulation of transcription, DNA-templated, response to vitamin A, response to lipopolysaccharide, acute-phase response, peptidyl-serine phosphorylation, response to axon injury, hemoglobin biosynthetic process, positive regulation of neuron differentiation, positive regulation of cell population proliferation, regulation of transcription from RNA polymerase II promoter in response to hypoxia, positive regulation of ERK1 and ERK2 cascade, positive regulation of neuron projection development, negative regulation of calcium ion transport into cytosol, negative regulation of myeloid cell apoptotic process, activation of protein kinase activity, embryo implantation, signal transduction, positive regulation of activated T cell proliferation, positive regulation of protein kinase activity, negative regulation of neuron death, apoptotic process, response to dexamethasone, cell population proliferation, erythrocyte differentiation, erythropoietin-mediated signaling pathway, positive regulation of tyrosine phosphorylation of STAT protein, regulation of signaling receptor activity, response to hypoxia, positive regulation of cell population proliferation, erythropoietin-mediated signaling pathway, hemoglobin biosynthetic process, positive regulation of Ras protein signal transduction, positive regulation of phosphatidylinositol 3-kinase signaling, positive regulation of Ras protein signal transduction[18][19][20][21][22][23][24][25][26][27][28][29][30][31]
Cell component
extracellular region, cell surface, cell body, extracellular space, extracellular space[14][15][16][17]
Encoded by
EPO
Encodes
erythropoietin
Found in taxon
Homo sapiens
Has part(s)
nitrogen, carbon, Erythropoietin/thrombopoeitin, conserved site[6][7][8]
Legal status (medicine)
boxed warning
Molecular function
hormone activity, protein kinase activator activity, protein binding, erythropoietin receptor binding, cytokine activity, cytokine activity, erythropoietin receptor binding, protein kinase activator activity[9][10][11][12][13]
🏷️ Also known as
en uniprot:P01588 en epoetin en erythropoietin en EPO ar إرثروبويتين ar اريثروبويتين ar إريثروبويتين ar EPO cs Erythropoetin cs Erythropoietin cs EPO cs Erytropoetin da Mircera da erythropoeitin da erythropoitin da erytropoietin da erythropoietin da erythropoethin de Erythropoeitin de Erythropoietin
🔖 Identifiers · 26
Library of Congress authority ID
sh85044756
GND ID
4152964-9
OpenAlex ID
C2778534260
BNCF Thesaurus ID
73525
Dewey Decimal Classification
573.155, 612.41
Ensembl protein ID
ENSP00000252723
Exact match
purl.uniprot.org
France 24 topic ID (French)
epo
Freebase ID
/m/01fwr3
Gran Enciclopèdia Catalana ID
eritropoetina
Gran Enciclopèdia Catalana ID (former scheme)
0103932
Great Russian Encyclopedia portal ID
eritropoetin-ea05f9
Show all 26 identifiers +14
Lex ID
epo, erythropoietin
Microsoft Academic ID (discontinued)
2778534260
NALT ID
28017
NDL Authority ID
00577035
National Library of Israel J9U ID
987007553190405171
PDB structure ID
1BUY, 1CN4, 1EER
RefSeq protein ID
NP_000790
UK Parliament thesaurus ID
9984
UNII
64FS3BFH5W
UniProt protein ID
P01588
WikiSkripta article ID
15467
WordNet 3.1 Synset ID
14874504-n
YSO ID
38860
Yale LUX ID
concept/9b4ad33e-73cf-44d6-8446-babbf8aba2ec

Report an error or request removal Lineage (PROV-JSON)

🔗 Connections
Biological process 5
ageing, apoptotic process, signal transduction, cell population proliferation, blood circulation
Cell component 2
extracellular space, extracellular space
Has part(s) 2
carbon, nitrogen
Subtypes 2
epoetin alfa, Methoxy polyethylene glycol-epoetin beta
Encodes 1
erythropoietin
Found in taxon 1
Homo sapiens
Instance of 1
gene
Legal status (medicine) 1
boxed warning
Molecular function 1
protein binding
← Encodes 1
erythropoietin
← Field of work 1
Harvey Lodish
Press Enter · cited answer in seconds

Summary

erythropoietin is a gene[1]. erythropoietin is a type of protein-coding gene[2].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . NCBI homo sapiens annotation release 107. Retrieved . wikidata.org.
  2. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . wikidata.org.
  5. [6] ↑ . wikidata.org.
  6. [7] ↑ . wikidata.org.
  7. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . Erythropoietin Stimulates Tumor Growth via EphB4.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . Inhibition of Erythrocyte Cation Channels by Erythropoietin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . Inhibition of Erythrocyte Cation Channels by Erythropoietin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] ↑ . Inhibition of Erythrocyte Cation Channels by Erythropoietin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] ↑ . Inhibition of Erythrocyte Cation Channels by Erythropoietin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [29] ↑ . Insulin-like Growth Factor-I Augments Erythropoietin-induced Proliferation through Enhanced Tyrosine Phosphorylation of STAT5. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [31] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). erythropoietin. Retrieved November 4, 2026, from https://4ort.xyz/entity/erythropoietin
MLA “erythropoietin.” 4ort.xyz Knowledge Graph, 4ort.xyz, 4 Nov. 2026, https://4ort.xyz/entity/erythropoietin.
BibTeX @misc{4ortxyz_erythropoietin_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{erythropoietin}}, year = {2026}, url = {https://4ort.xyz/entity/erythropoietin}, note = {Accessed: 2026-11-04}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): erythropoietin — https://4ort.xyz/entity/erythropoietin (retrieved 2026-11-04)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 24w ago · Twofivesixbot bot · 2026-05-18 view diff on Wikidata ↗
    Instance of → gene
    Found in taxon → Homo sapiens
    Has part(s) → nitrogen, carbon, Erythropoietin/thrombopoeitin, conserved site
    Part of → erythropoietin, four-helical cytokine-like, core, Erythropoietin/thrombopoeitin, conserved site, protein family
    + 13 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-update-qualifiers:1||1|6 */ YSO ID: 38860, mv to monolingual text names on YSO statements"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.