ERCC4

protein-coding gene in the species Homo sapiens
Gene gene Q17917469
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ERCC4

Summary

ERCC4 is a gene[1]. ERCC4 ranks in the top 2% of gene entities by monthly Wikipedia readership (27 views/month).[2]

Key Facts

  • ERCC4's instance of is recorded as gene[3].
  • ERCC4's instance of is recorded as protein[4].
  • ERCC4 is a type of protein-coding gene[5].
  • ERCC4 is part of Cell cycle checkpoint protein, Rad1[6].
  • ERCC4's EC enzyme number is recorded as 3.1.11.2[7].
  • ERCC4's HomoloGene ID is recorded as 3836[8].
  • ERCC4's genomic start is recorded as 14014014[9].
  • ERCC4's genomic start is recorded as 13920138[10].
  • ERCC4's genomic end is recorded as 14046202[11].
  • ERCC4's genomic end is recorded as 13952348[12].
  • ERCC4's molecular function is recorded as damaged DNA binding[13].
  • ERCC4's molecular function is recorded as exodeoxyribonuclease III activity[14].
  • ERCC4's molecular function is recorded as protein binding[15].
  • ERCC4's molecular function is recorded as 3'-5' exonuclease activity[16].
  • ERCC4's molecular function is recorded as nuclease activity[17].
  • ERCC4's molecular function is recorded as exonuclease activity[18].
  • ERCC4's molecular function is recorded as hydrolase activity[19].
  • ERCC4's molecular function is recorded as 3'-5' exonuclease activity[20].
  • ERCC4's cell component is recorded as intracellular membrane-bounded organelle[21].
  • ERCC4's cell component is recorded as chromosome[22].
  • ERCC4's cell component is recorded as nucleoplasm[23].
  • ERCC4's cell component is recorded as checkpoint clamp complex[24].
  • ERCC4's cell component is recorded as nucleus[25].
  • ERCC4's biological process is recorded as substantia nigra development[26].
  • ERCC4's biological process is recorded as DNA damage checkpoint signaling[27].

Why It Matters

ERCC4 ranks in the top 2% of gene entities by monthly Wikipedia readership (27 views/month).[2] ERCC4 is known by 18 alternative names across languages and contexts.[28]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . ensembl Release 106. wikidata.org.
  2. [4] . Q905695. Retrieved . wikidata.org.
  3. [5] . Ensembl Release 87. wikidata.org.
  4. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] . wikidata.org.
  6. [8] . Q20641742. Retrieved . wikidata.org.
  7. [9] . ensembl Release 106. wikidata.org.
  8. [10] . ensembl Release 106. wikidata.org.
  9. [11] . ensembl Release 106. wikidata.org.
  10. [12] . ensembl Release 106. wikidata.org.
  11. [13] . Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . A Human Homologue of the Schizosaccharomyces pombe rad1+ Checkpoint Gene Encodes an Exonuclease. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . A Human Homologue of the Schizosaccharomyces pombe rad1+ Checkpoint Gene Encodes an Exonuclease. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . Quantitative Proteomic Analysis of Human Substantia Nigra in Alzheimer’s Disease, Huntington’s Disease and Multiple Sclerosis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). ERCC4. Retrieved May 3, 2026, from https://4ort.xyz/entity/ercc4
MLA “ERCC4.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/ercc4.
BibTeX @misc{4ortxyz_ercc4_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{ERCC4}}, year = {2026}, url = {https://4ort.xyz/entity/ercc4}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): ERCC4 — https://4ort.xyz/entity/ercc4 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/ercc4 · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 1d ago · Mathieu Kappler · 2026-05-20 view diff on Wikidata ↗
    Genetic association conduct disorder, xeroderma pigmentosum group F, XFE progeroid syndrome +1
    Part of
    Subclass of
    Biological process substantia nigra development, DNA damage checkpoint signaling, cellular response to DNA damage stimulus +9
    + 14 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||gsw */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/32527|batch #32527]]: human gene name and description in Alemannic"
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