egl-9 family hypoxia inducible factor 1

mammalian protein found in Homo sapiens
Protein protein Q21110136
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egl-9 family hypoxia inducible factor 1

Summary

egl-9 family hypoxia inducible factor 1 is a protein[1].

Key Facts

  • egl-9 family hypoxia inducible factor 1's instance of is recorded as protein[2].
  • egl-9 family hypoxia inducible factor 1's physically interacts with is recorded as enarodustat[3].
  • egl-9 family hypoxia inducible factor 1's physically interacts with is recorded as daprodustat[4].
  • egl-9 family hypoxia inducible factor 1's physically interacts with is recorded as molidustat[5].
  • egl-9 family hypoxia inducible factor 1's physically interacts with is recorded as roxadustat[6].
  • egl-9 family hypoxia inducible factor 1 is part of Zinc finger, MYND-type, protein family[7].
  • egl-9 family hypoxia inducible factor 1 is part of Prolyl 4-hydroxylase, alpha subunit, protein family[8].
  • egl-9 family hypoxia inducible factor 1 is part of Oxoglutarate/iron-dependent dioxygenase family[9].
  • egl-9 family hypoxia inducible factor 1 comprises zinc finger, MYND-type[10].
  • egl-9 family hypoxia inducible factor 1 comprises Oxoglutarate/iron-dependent dioxygenase[11].
  • egl-9 family hypoxia inducible factor 1 comprises Prolyl 4-hydroxylase, alpha subunit[12].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as 2-oxoglutarate-dependent dioxygenase activity[13].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as iron ion binding[14].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as L-ascorbic acid binding[15].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as dioxygenase activity[16].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as metal ion binding[17].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as protein binding[18].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen[19].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as peptidyl-proline dioxygenase activity[20].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as enzyme binding[21].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as oxidoreductase activity[22].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as peptidyl-proline 4-dioxygenase activity[23].
  • egl-9 family hypoxia inducible factor 1's molecular function is recorded as ferrous iron binding[24].
  • egl-9 family hypoxia inducible factor 1's cell component is recorded as cytoplasm[25].
  • egl-9 family hypoxia inducible factor 1's cell component is recorded as nucleus[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  3. [4] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  4. [5] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  5. [6] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  6. [7] . wikidata.org.
  7. [8] . wikidata.org.
  8. [9] . wikidata.org.
  9. [10] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . A conserved family of prolyl-4-hydroxylases that modify HIF. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . 1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). egl-9 family hypoxia inducible factor 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/egl-9-family-hypoxia-inducible-factor-1-q21110136
MLA “egl-9 family hypoxia inducible factor 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/egl-9-family-hypoxia-inducible-factor-1-q21110136.
BibTeX @misc{4ortxyz_egl-9-family-hypoxia-inducible-factor-1-q21110136_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{egl-9 family hypoxia inducible factor 1}}, year = {2026}, url = {https://4ort.xyz/entity/egl-9-family-hypoxia-inducible-factor-1-q21110136}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): egl-9 family hypoxia inducible factor 1 — https://4ort.xyz/entity/egl-9-family-hypoxia-inducible-factor-1-q21110136 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/egl-9-family-hypoxia-inducible-factor-1-q21110136 · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 8d ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from
    Encoded by EGLN1
    Wikidata description mammalian protein found in Homo sapiens
    Molecular function 2-oxoglutarate-dependent dioxygenase activity, iron ion binding, L-ascorbic acid binding +9
    + 13 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 1.14.11.29, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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