Cystatin C

mammalian protein found in Homo sapiens
Protein protein Q413243
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Cystatin C

Summary

Cystatin C is a protein[1]. It ranks in the top 6% of protein entities by monthly Wikipedia readership (744 views/month).[2]

Key Facts

  • Cystatin C's instance of is recorded as protein[3].
  • Cystatin C is part of Cystatin[4].
  • Cystatin C is part of cystatins[5].
  • Cystatin C is part of Proteinase inhibitor I25, cystatin, conserved site, protein family[6].
  • Cystatin C comprises Cystatin domain[7].
  • Cystatin C comprises Proteinase inhibitor I25, cystatin, conserved site[8].
  • Cystatin C's molecular function is recorded as peptidase inhibitor activity[9].
  • Cystatin C's molecular function is recorded as cysteine-type endopeptidase inhibitor activity[10].
  • Cystatin C's molecular function is recorded as amyloid-beta binding[11].
  • Cystatin C's molecular function is recorded as protein binding[12].
  • Cystatin C's molecular function is recorded as identical protein binding[13].
  • Cystatin C's molecular function is recorded as endopeptidase inhibitor activity[14].
  • Cystatin C's molecular function is recorded as protease binding[15].
  • Cystatin C's molecular function is recorded as protease binding[16].
  • Cystatin C's molecular function is recorded as peptidase inhibitor activity[17].
  • Cystatin C's cell component is recorded as extracellular region[18].
  • Cystatin C's cell component is recorded as extracellular exosome[19].
  • Cystatin C's cell component is recorded as tertiary granule lumen[20].
  • Cystatin C's cell component is recorded as ficolin-1-rich granule lumen[21].
  • Cystatin C's cell component is recorded as basement membrane[22].
  • Cystatin C's cell component is recorded as extracellular space[23].
  • Cystatin C's cell component is recorded as cytoplasm[24].
  • Cystatin C's cell component is recorded as lysosome[25].
  • Cystatin C's cell component is recorded as multivesicular body[26].
  • Cystatin C's cell component is recorded as endoplasmic reticulum[27].

Why It Matters

Cystatin C ranks in the top 6% of protein entities by monthly Wikipedia readership (744 views/month).[2] It has Wikipedia articles in 11 language editions, a strong signal of global cultural recognition.[28] It is known by 14 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] . wikidata.org.
  4. [6] . wikidata.org.
  5. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [9] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] . Cystatin C modulates cerebral beta-amyloidosis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . Megalin-mediated endocytosis of cystatin C in proximal tubule cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . The pentapeptide LQVVR plays a pivotal role in human cystatin C fibrillization. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . Human brain cathepsin H as a neuropeptide and bradykinin metabolizing enzyme. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . Structural basis for the biological specificity of cystatin C. Identification of leucine 9 in the N-terminal binding region as a selectivity-conferring residue in the inhibition of mammalian cysteine peptidases. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . Structural basis for the biological specificity of cystatin C. Identification of leucine 9 in the N-terminal binding region as a selectivity-conferring residue in the inhibition of mammalian cysteine peptidases. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Cystatin C. Retrieved May 3, 2026, from https://4ort.xyz/entity/cystatin-c
MLA “Cystatin C.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/cystatin-c.
BibTeX @misc{4ortxyz_cystatin-c_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Cystatin C}}, year = {2026}, url = {https://4ort.xyz/entity/cystatin-c}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Cystatin C — https://4ort.xyz/entity/cystatin-c (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/cystatin-c · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 4d ago · Twofivesixbot bot · 2026-05-19 view diff on Wikidata ↗
    Found in taxon Homo sapiens
    Encoded by CST3
    Instance of
    Aliases
    + 8 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-update-qualifiers:1||1|5 */ [[Property:P2347]]: 21508, mv to monolingual text names on YSO statements"
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