Crigler-Najjar syndrome

bilirubin metabolic disorder that involves a build up of bilirubin as bilirubin is not being broken down as a result of a lack or deficiency of the enzyme uridine diphosphate glycosyltransferase (UGT)
MedicalCondition rare_disease Q1140000
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Summary

Crigler-Najjar syndrome is a rare disease[1]. It has Wikipedia articles in 16 language editions, a strong signal of global cultural recognition.[2]

Key Facts

  • Crigler-Najjar syndrome's instance of is recorded as rare disease[3].
  • Crigler-Najjar syndrome's instance of is recorded as class of disease[4].
  • John Fielding Crigler is named after Crigler-Najjar syndrome[5].
  • Victor Assad Najjar is named after Crigler-Najjar syndrome[6].
  • Crigler-Najjar syndrome is a type of bilirubin metabolic disorder[7].
  • Crigler-Najjar syndrome is a type of disease[8].
  • Crigler-Najjar syndrome's NCI Thesaurus ID is recorded as C84656[9].
  • Crigler-Najjar syndrome's health specialty is recorded as pediatrics[10].
  • Crigler-Najjar syndrome's health specialty is recorded as hepatology[11].
  • Crigler-Najjar syndrome's genetic association is recorded as UGT1A1[12].
  • Crigler-Najjar syndrome's exact match is recorded as http://purl.obolibrary.org/obo/DOID_3803[13].
  • Crigler-Najjar syndrome's exact match is recorded as http://identifiers.org/doid/DOID:3803[14].
  • Crigler-Najjar syndrome's on focus list of Wikimedia project is recorded as WikiProject Medicine[15].

Why It Matters

Crigler-Najjar syndrome has Wikipedia articles in 16 language editions, a strong signal of global cultural recognition.[2] It is known by 25 alternative names across languages and contexts.[16]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . wikidata.org.
  2. [4] ↑ . wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . Disease Ontology. Retrieved . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . Disease Ontology. Retrieved . wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . wikidata.org.
  10. [12] ↑ . Identification of an A-to-G missense mutation in exon 2 of the UGT1 gene complex that causes Crigler-Najjar syndrome type 2. wikidata.org.
  11. [13] ↑ . Disease Ontology. Retrieved . wikidata.org.
  12. [14] ↑ . Identifiers.org. registry.identifiers.org. Provenance: wikidata.org.
  13. [15] ↑ . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata sitelinks. wikidata.org.
  2. [16] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Crigler-Najjar syndrome. Retrieved October 11, 2026, from https://4ort.xyz/entity/crigler-najjar-syndrome
MLA “Crigler-Najjar syndrome.” 4ort.xyz Knowledge Graph, 4ort.xyz, 11 Oct. 2026, https://4ort.xyz/entity/crigler-najjar-syndrome.
BibTeX @misc{4ortxyz_crigler-najjar-syndrome_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Crigler-Najjar syndrome}}, year = {2026}, url = {https://4ort.xyz/entity/crigler-najjar-syndrome}, note = {Accessed: 2026-10-11}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Crigler-Najjar syndrome — https://4ort.xyz/entity/crigler-najjar-syndrome (retrieved 2026-10-11)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 14w ago · JhealdBatch bot · 2026-07-03 view diff on Wikidata ↗
    Subclass of → bilirubin metabolic disorder, disease
    Named after → —
    Health specialty → pediatrics, hepatology
    Genetic association → UGT1A1
    + 6 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update:0| */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/39732|batch #39732]]: rm redundant subclass"
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