CREB binding protein

mammalian protein found in Homo sapiens

Protein protein Q906517

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CREB binding protein

Summary

CREB binding protein is a protein^[1]. It has Wikipedia articles in 8 language editions, a strong signal of global cultural recognition.^[2]

Key Facts

CREB binding protein's instance of is recorded as protein^[3].
CREB binding protein is part of Histone acetyltransferase Rtt109/CBP^[4].
CREB binding protein is part of TAZ domain superfamily^[5].
CREB binding protein is part of Nuclear receptor coactivator, interlocking^[6].
CREB binding protein is part of Nuclear receptor coactivator, CREB-bp-like, interlocking domain superfamily^[7].
CREB binding protein is part of Coactivator CBP, KIX domain superfamily^[8].
CREB binding protein is part of Bromodomain-like superfamily^[9].
CREB binding protein is part of Zinc finger, RING/FYVE/PHD-type^[10].
CREB binding protein is part of CBP/p300, atypical RING domain superfamily^[11].
CREB binding protein is part of Zinc finger, ZZ-type, protein family^[12].
CREB binding protein is part of CREB-binding protein/p300, atypical RING domain, protein family^[13].
CREB binding protein is part of CBP/p300-type histone acetyltransferase domain, protein family^[14].
CREB binding protein is part of Nuclear receptor coactivator, CREB-bp-like, interlocking, protein family^[15].
CREB binding protein is part of Coactivator CBP, KIX domain, protein family^[16].
CREB binding protein is part of Zinc finger, TAZ-type, protein family^[17].
CREB binding protein is part of bromodomain protein family^[18].
CREB binding protein is part of Bromodomain, conserved site, protein family^[19].
CREB binding protein comprises CREB-binding protein/p300, atypical RING domain^[20].
CREB binding protein comprises bromodomain^[21].
CREB binding protein comprises Zinc finger, ZZ-type^[22].
CREB binding protein comprises Nuclear receptor coactivator, CREB-bp-like, interlocking^[23].
CREB binding protein comprises Bromodomain, conserved site^[24].
CREB binding protein comprises Zinc finger, TAZ-type^[25].
CREB binding protein comprises Coactivator CBP, KIX domain^[26].
CREB binding protein comprises CBP/p300-type histone acetyltransferase domain^[27].

Why It Matters

CREB binding protein has Wikipedia articles in 8 language editions, a strong signal of global cultural recognition.^[2] It is known by 12 alternative names across languages and contexts.^[28]

⭐ Popularity Graph

2/100 established

🌐 Wiki Languages

11 / 423 langs

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cAMP response element binding protein

p300-CBP coactivator family

Quick Facts

Instance of protein

Part of Histone acetyltransferase Rtt109/CBP, TAZ domain superfamily, Nuclear receptor coactivator, interlocking, Nuclear receptor coactivator, CREB-bp-like, interlocking domain superfamily, Coactivator CBP, KIX domain superfamily, Bromodomain-like superfamily, Zinc finger, RING/FYVE/PHD-type, CBP/p300, atypical RING domain superfamily, Zinc finger, ZZ-type, protein family, CREB-binding protein/p300, atypical RING domain, protein family, CBP/p300-type histone acetyltransferase domain, protein family, Nuclear receptor coactivator, CREB-bp-like, interlocking, protein family, Coactivator CBP, KIX domain, protein family, Zinc finger, TAZ-type, protein family, bromodomain protein family, Bromodomain, conserved site, protein family

Properties

Biological process Notch signaling pathway, response to hypoxia, regulation of transcription, DNA-templated, rhythmic process, cellular response to UV, embryonic digit morphogenesis, N-terminal peptidyl-lysine acetylation, stimulatory C-type lectin receptor signaling pathway, negative regulation of transcription by RNA polymerase II, transcription, DNA-templated, positive regulation of transcription, DNA-templated, regulation of smoothened signaling pathway, histone acetylation, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of cellular response to heat, transcription initiation from RNA polymerase II promoter, viral process, positive regulation of type I interferon production, signal transduction, protein acetylation, homeostatic process, beta-catenin-TCF complex assembly, regulation of apoptotic process, positive regulation of transcription by RNA polymerase II, regulation of lipid metabolic process, protein destabilization, regulation of myeloid cell differentiation, protein acetylation, positive regulation of transcription of Notch receptor target, positive regulation of transforming growth factor beta receptor signaling pathway, positive regulation of Notch signaling pathway, protein-containing complex assembly

Cell component cytoplasm, nucleoplasm, histone acetyltransferase complex, nucleus, nuclear body

Ec enzyme number 2.3.1.48

Encoded by CREBBP

Found in taxon Homo sapiens

Has part(s) CREB-binding protein/p300, atypical RING domain, bromodomain, Zinc finger, ZZ-type, Nuclear receptor coactivator, CREB-bp-like, interlocking, Bromodomain, conserved site, Zinc finger, TAZ-type, Coactivator CBP, KIX domain, CBP/p300-type histone acetyltransferase domain

Molecular function transferase activity, transcription coactivator activity, MRF binding, transcription coactivator activity, zinc ion binding, p53 binding, transcription factor binding, chromatin binding, cis-regulatory region sequence-specific DNA binding, transcription coregulator activity, signal transducer activity, metal ion binding, histone acetyltransferase activity, damaged DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, protein binding, acetyltransferase activity, acyltransferase activity, peptide N-acetyltransferase activity, DNA-binding transcription factor activity, transcription corepressor activity, histone acetyltransferase activity

External References (11)

Ensembl protein id ENSP00000262367, ENSP00000371502, ENSP00000458254, ENSP00000459490, ENSP00000460474, ENSP00000461002, ENSP00000490244

Freebase id /m/03bxv8s

Hgnc id 2348

Mesh descriptor id D050882

Mesh tree code D08.811.913.050.134.415.500.575.249, D12.776.930.680.300

Microsoft academic id (discontinued) 2776603820

Openalex id C2776603820

Pdb structure id 1JSP, 1LIQ, 1RDT, 1WO3, 1WO4, 1WO5, 1WO6, 1WO7, 2D82, 2KJE, 2KWF, 2L84, 2L85, 2LXS, 2LXT, 2RNY, 3DWY, 3P1C, 3P1D, 3P1E, 3P1F, 3SVH, 4A9K, 4N3W, 4N4F, 4NR4, 4NR5, 4NR6, 4NR7, 4NYV, 4NYW, 4NYX, 4OUF, 4TQN, 4TS8, 4WHU, 5JEM, 5I8B, 5I89, 5I86, 4YK0, 5CGP, 5I8G, 2N1A, 5I83, 1ZOQ, 5DBM

Refseq protein id NP_001073315, NP_004371, XP_005255181, XP_005255182, XP_006720911, XP_011520683, XP_011520684, XP_016878433

Umls cui C0256079

Uniprot protein id Róbert Szelepcsényi

🌐 Available in 8 languages

enCREB-binding protein deCREB-Binding-Protein esCREBBP fiCREB jaCREB結合タンパク質 nlCREB-bindingseiwit ruCREBBP ukCREBBP

🏷️ Also known as

en RSTS en CBP en CREB-binding protein en CREBBP en Cyclic AMP Response Element-Binding Protein en histone lysine acetyltransferase CREBBP en KAT3A en protein-lysine acetyltransferase CREBBP de CREB Binding Protein es Proteina de union a CREB es Proteína de unión a CREB zh CREB结合蛋白

🔗 Connections

Cell component 4

nucleus, cytoplasm, nucleoplasm, nuclear body

Biological process 2

signal transduction, Notch signaling pathway

Found in taxon 1

Homo sapiens

Has part(s) 1

bromodomain

Instance of 1

protein

Molecular function 1

protein binding

Uniprot protein id 1

Róbert Szelepcsényi

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). CREB binding protein. Retrieved May 3, 2026, from https://4ort.xyz/entity/creb-binding-protein

MLA

“CREB binding protein.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/creb-binding-protein.

BibTeX

@misc{4ortxyz_creb-binding-protein_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{CREB binding protein}}, year = {2026}, url = {https://4ort.xyz/entity/creb-binding-protein}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): CREB binding protein — https://4ort.xyz/entity/creb-binding-protein (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/creb-binding-protein · Last refreshed: May 3, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

28d ago · Boghog · 2026-07-23 view diff on Wikidata ↗

Instance of → —

Part of → —

Encoded by → CREBBP

Biological process → Notch signaling pathway, response to hypoxia, regulation of transcription, DNA-templated +29

+ 9 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.3.1.48, [[:toollabs:quickstatements/#/batch/261446|batch #261446]]"

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CREB binding protein

CREB binding protein

Summary

Key Facts

Why It Matters

Related Entities

References

Direct Wikidata claims

Class ancestry

Aggregate / graph-position facts

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