CD4 molecule

mammalian protein found in Homo sapiens

Protein protein Q412587

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CD4 molecule

Summary

CD4 molecule is a protein^[1]. It ranks in the top 6% of protein entities by monthly Wikipedia readership (171 views/month).^[2]

Key Facts

CD4 molecule's instance of is recorded as protein^[3].
CD4 molecule's UniProt protein ID is recorded as P01730^[4].
CD4 molecule's part of is recorded as T-cell surface antigen CD4^[5].
CD4 molecule's part of is recorded as Immunoglobulin-like fold^[6].
CD4 molecule's part of is recorded as Immunoglobulin-like domain superfamily^[7].
CD4 molecule's part of is recorded as immunoglobulin subtype, protein family^[8].
CD4 molecule's part of is recorded as Immunoglobulin V-set domain, protein family^[9].
CD4 molecule's part of is recorded as T cell CD4 receptor C-terminal region, protein family^[10].
CD4 molecule's part of is recorded as Immunoglobulin C2-set, protein family^[11].
CD4 molecule's part of is recorded as CD4, extracellular domain, protein family^[12].
CD4 molecule's part of is recorded as Immunoglobulin subtype 2, protein family^[13].
CD4 molecule's part of is recorded as immunoglobulin-like domain, protein family^[14].
CD4 molecule's part of is recorded as Immunoglobulin domain, protein family^[15].
CD4 molecule's Commons category is recorded as CD4^[16].
CD4 molecule's has part is recorded as immunoglobulin domain^[17].
CD4 molecule's has part is recorded as Immunoglobulin C2-set^[18].
CD4 molecule's has part is recorded as immunoglobulin subtype 2^[19].
CD4 molecule's has part is recorded as immunoglobulin-like domain^[20].
CD4 molecule's has part is recorded as T cell CD4 receptor C-terminal region^[21].
CD4 molecule's has part is recorded as CD4, extracellular^[22].
CD4 molecule's has part is recorded as immunoglobulin V-set domain^[23].
CD4 molecule's has part is recorded as immunoglobulin subtype^[24].
CD4 molecule's RefSeq protein ID is recorded as NP_000607^[25].
CD4 molecule's RefSeq protein ID is recorded as NP_001181943^[26].
CD4 molecule's RefSeq protein ID is recorded as NP_001181944^[27].

Why It Matters

CD4 molecule ranks in the top 6% of protein entities by monthly Wikipedia readership (171 views/month).^[2] It has Wikipedia articles in 18 language editions, a strong signal of global cultural recognition.^[28] It is known by 19 alternative names across languages and contexts.^[29]

⭐ Popularity Graph

3/100 established

🌐 Wiki Languages

25 / 423 langs top 10%

📈 Wikipedia Views · last 219h

589/mo 856/yr

🔗 Readers Also Explored · clickstream

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📊 Google Search Volume

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Quick Facts

Instance of protein

Part of T-cell surface antigen CD4, Immunoglobulin-like fold, Immunoglobulin-like domain superfamily, immunoglobulin subtype, protein family, Immunoglobulin V-set domain, protein family, T cell CD4 receptor C-terminal region, protein family, Immunoglobulin C2-set, protein family, CD4, extracellular domain, protein family, Immunoglobulin subtype 2, protein family, immunoglobulin-like domain, protein family, Immunoglobulin domain, protein family

Properties

Biological process transmembrane receptor protein tyrosine kinase signaling pathway, defense response to Gram-negative bacterium, positive regulation of protein kinase activity, mitigation of host defenses by virus, positive regulation of calcium-mediated signaling, signal transduction, helper T cell enhancement of adaptive immune response, T cell selection, response to estradiol, induction by virus of host cell-cell fusion, adaptive immune response, response to vitamin D, T cell differentiation, cell surface receptor signaling pathway, positive regulation of T cell proliferation, positive regulation of peptidyl-tyrosine phosphorylation, enzyme linked receptor protein signaling pathway, T cell activation, positive regulation of T cell activation, maintenance of protein location in cell, cytokine production, T cell receptor signaling pathway, immune system process, positive regulation of calcium ion transport into cytosol, regulation of T cell activation, immune response, cell adhesion, viral process, fusion of virus membrane with host plasma membrane, membrane organization, positive regulation of protein phosphorylation, positive regulation of kinase activity, interleukin-15-mediated signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of MAPK cascade, positive regulation of monocyte differentiation, positive regulation of transcription, DNA-templated, positive regulation of viral entry into host cell, regulation of calcium ion transport, positive regulation of ERK1 and ERK2 cascade, cellular response to granulocyte macrophage colony-stimulating factor stimulus, cytokine-mediated signaling pathway, interleukin-15-mediated signaling pathway, T cell activation, positive regulation of ERK1 and ERK2 cascade, macrophage differentiation

Cell component endoplasmic reticulum lumen, integral component of membrane, early endosome, membrane, cell surface, endoplasmic reticulum membrane, membrane raft, T cell receptor complex, external side of plasma membrane, plasma membrane, clathrin-coated vesicle membrane, integral component of plasma membrane, external side of plasma membrane, membrane raft

Encoded by CD4

Exact match purl.uniprot.org

Found in taxon Homo sapiens

Has part(s) immunoglobulin domain, Immunoglobulin C2-set, immunoglobulin subtype 2, immunoglobulin-like domain, T cell CD4 receptor C-terminal region, CD4, extracellular, immunoglobulin V-set domain, immunoglobulin subtype

Has parts immunoglobulin domain, Immunoglobulin C2-set, immunoglobulin subtype 2, immunoglobulin-like domain, T cell CD4 receptor C-terminal region, CD4, extracellular, immunoglobulin V-set domain, immunoglobulin subtype

Molecular function transmembrane signaling receptor activity, virus receptor activity, protein homodimerization activity, zinc ion binding, extracellular matrix structural constituent, enzyme binding, immunoglobulin binding, protein binding, coreceptor activity, interleukin-16 binding, interleukin-16 receptor activity, MHC class II protein binding, identical protein binding, protein tyrosine kinase binding, signaling receptor activity, protein kinase binding, signaling receptor binding, MHC class II protein binding, protein tyrosine kinase binding

External References (7)

Ensembl protein id ENSP00000011653, ENSP00000440720, ENSP00000445167

Freebase id /m/063m46, /m/02kfly8

Pdb structure id 1CDH, 1CDI, 1CDJ, 1CDU, 1CDY, 1G9M, 1G9N, 1GC1, 1JL4, 1Q68, 1RZJ, 1RZK, 1WIO, 1WIP, 1WIQ, 2B4C, 2JKR, 2JKT, 2KLU, 2NXY, 2NXZ, 2NY0, 2NY1, 2NY2, 2NY3, 2NY4, 2NY5, 2NY6, 2QAD, 3B71, 3CD4, 3JWD, 3JWO, 3LQA, 3O2D, 3S5L, 3T0E, 4JM2, 1WBR, 3S4S, 4H8W, 4P9H, 4Q6I, 4R2G, 4R4H, 4RQS, 3J70, 5A7X, 5A8H, 5CAY

Refseq protein id NP_000607, NP_001181943, NP_001181944, NP_001181945, NP_001181946, NP_001369634, NP_001369635, NP_001369636, NP_001369643

Transporter classification database id 8.A.23.2.1

Umls cui C0003323

Uniprot protein id P01730

🌐 Available in 18 languages

enCD4 arكتلة التمايز 4 csCD4 daCD4 deCD4-Rezeptor esCD4 fiCD4 frCD4 heCD4 idCD4 itCD4 jaCD4 koCD4 plCD4 ptCD4 ruCD4 ukCD4 zh分化群4

🏷️ Also known as

en CD4 receptor en T-cell surface antigen T4/Leu-3 en T-cell surface glycoprotein CD4 en CD4 en CD4 antigen (p55) en CD4 Antigens en CD4 protein cs CD4+ cs CD4+ T-lymfocyty de CD4 es Cumulo de diferenciacion 4 es Cumulo de diferenciación 4 es Cúmulo de diferenciacion 4 es Cúmulo de diferenciación 4 fr Recepteur CD4 fr Récepteur CD4 it L3T4 it W3/25 zh CD4

🔗 Connections

Biological process 3

signal transduction, immune response, cell adhesion

Cell component 3

plasma membrane, membrane raft, membrane raft

Found in taxon 1

Homo sapiens

Has part(s) 1

immunoglobulin domain

Instance of 1

protein

Molecular function 1

protein binding

Part of 1

Immunoglobulin-like domain superfamily

← Entry receptor 1

HIV

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). CD4 molecule. Retrieved May 3, 2026, from https://4ort.xyz/entity/cd4-molecule

MLA “CD4 molecule.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/cd4-molecule.

BibTeX

@misc{4ortxyz_cd4-molecule_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{CD4 molecule}}, year = {2026}, url = {https://4ort.xyz/entity/cd4-molecule}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): CD4 molecule — https://4ort.xyz/entity/cd4-molecule (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/cd4-molecule · Last refreshed: May 3, 2026

CD4 molecule

CD4 molecule

Summary

Key Facts

Why It Matters

References

Direct Wikidata claims

Class ancestry

Aggregate / graph-position facts

📑 Cite this page