Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

mammalian protein found in Mus musculus

Protein protein Q21499275

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Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

Summary

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 is a protein^[1].

Key Facts

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's instance of is recorded as protein^[2].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's subclass of is recorded as protein^[3].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's UniProt protein ID is recorded as O35740^[4].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's part of is recorded as CITED^[5].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's RefSeq protein ID is recorded as NP_034958^[6].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's RefSeq protein ID is recorded as XP_036011557^[7].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as transcription corepressor activity^[8].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as DNA-binding transcription factor activity^[9].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as transcription coactivator activity^[10].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as transcription coregulator activity^[11].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as transcription corepressor activity^[12].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as chromatin binding^[13].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as LBD domain binding^[14].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as protein binding^[15].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as histone acetyltransferase binding^[16].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as SMAD binding^[17].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as transcription coactivator activity^[18].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as protein domain specific binding^[19].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's molecular function is recorded as transcription coactivator activity^[20].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's cell component is recorded as nucleus^[21].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's cell component is recorded as cytoplasm^[22].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's cell component is recorded as protein-containing complex^[23].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's cell component is recorded as nucleus^[24].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's cell component is recorded as cytoplasm^[25].
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2's cell component is recorded as nucleus^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of CITED

Properties

Biological process positive regulation of transforming growth factor beta receptor signaling pathway, cranial nerve morphogenesis, regulation of transcription by RNA polymerase II, cardiac neural crest cell development involved in heart development, outflow tract morphogenesis, vasculogenesis, heart looping, embryonic process involved in female pregnancy, blood vessel development, granulocyte differentiation, positive regulation of peroxisome proliferator activated receptor signaling pathway, cell population proliferation, transforming growth factor beta receptor signaling pathway, regulation of transcription, DNA-templated, ventricular septum development, kidney development, pulmonary artery morphogenesis, thymus development, cardiac septum morphogenesis, ventricular septum morphogenesis, in utero embryonic development, spleen development, transcription, DNA-templated, morphogenesis of an epithelium, positive regulation of transcription, DNA-templated, development of the heart, central nervous system development, branching involved in ureteric bud morphogenesis, positive regulation of cell cycle, regulation of animal organ formation, lens morphogenesis in camera-type eye, sex-determination system, embryonic camera-type eye morphogenesis, neural tube formation, nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry, adrenal cortex formation, cell differentiation, male gonad development, peripheral nervous system development, positive regulation of cell-cell adhesion, endocardial cushion development, embryonic placenta development, negative regulation of apoptotic process, negative regulation of transcription by RNA polymerase II, response to fluid shear stress, response to estrogen, negative regulation of cell migration, trophectodermal cell differentiation, hematopoietic progenitor cell differentiation, skeletal muscle cell differentiation, negative regulation of transcription from RNA polymerase II promoter in response to hypoxia, negative regulation of transcription, DNA-templated, positive regulation of male gonad development, response to hypoxia, determination of heart left/right asymmetry, embryonic heart tube left/right pattern formation, bone morphogenesis, adrenal gland development, multicellular organism development, neural tube closure, determination of left/right symmetry, vasculature development, decidualization, leukocyte differentiation, liver development, left/right axis specification, positive regulation of transcription by RNA polymerase II, erythrocyte development, response to mechanical stimulus, cellular response to growth factor stimulus, positive regulation of gene expression, negative regulation of gene expression, transcription by RNA polymerase II, negative regulation of cardiac muscle cell proliferation, positive regulation of nucleic acid-templated transcription, regulation of transcription by RNA polymerase II, sex-determination system

Cell component nucleus, cytoplasm, protein-containing complex, nucleus, cytoplasm, nucleus

Encoded by Cited2

Found in taxon house mouse

Imported from wholeness_audit_2026-05-02

Molecular function transcription corepressor activity, DNA-binding transcription factor activity, transcription coactivator activity, transcription coregulator activity, transcription corepressor activity, chromatin binding, LBD domain binding, protein binding, histone acetyltransferase binding, SMAD binding, transcription coactivator activity, protein domain specific binding, transcription coactivator activity

External References (3)

Ensembl protein id ENSMUSP00000038405, ENSMUSP00000151452, ENSMUSP00000151600

Refseq protein id NP_034958, XP_036011557

Uniprot protein id O35740

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — UniProt protein ID (P352): O35740. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — part of (P361): CITED. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — RefSeq protein ID (P637): NP_034958. Q20641742. Retrieved 2022-03-20. wikidata.org.
[7] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — RefSeq protein ID (P637): XP_036011557. Q20641742. Retrieved 2022-03-20. wikidata.org.
[8] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): transcription corepressor activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): DNA-binding transcription factor activity. MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): transcription coactivator activity. Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): transcription coregulator activity. Folic acid prevents exencephaly in Cited2 deficient mice. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): transcription corepressor activity. GOA. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): chromatin binding. Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): LBD domain binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): protein binding. Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): histone acetyltransferase binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): SMAD binding. Cited2 modulates TGF-beta-mediated upregulation of MMP9. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): transcription coactivator activity. GOA. Retrieved 2018-07-16. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): protein domain specific binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — molecular function (P680): transcription coactivator activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — cell component (P681): nucleus. Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Retrieved 2018-06-21. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — cell component (P681): cytoplasm. Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Retrieved 2018-06-21. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — cell component (P681): protein-containing complex. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — cell component (P681): nucleus. GOA. Retrieved 2018-07-16. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — cell component (P681): cytoplasm. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — cell component (P681): nucleus. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/cbp-p300-interacting-transactivator-with-glu-asp-rich-carboxy-terminal-domain-2

MLA

“Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/cbp-p300-interacting-transactivator-with-glu-asp-rich-carboxy-terminal-domain-2.

BibTeX

@misc{4ortxyz_cbp-p300-interacting-transactivator-with-glu-asp-rich-carboxy-terminal-domain-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2}}, year = {2026}, url = {https://4ort.xyz/entity/cbp-p300-interacting-transactivator-with-glu-asp-rich-carboxy-terminal-domain-2}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 — https://4ort.xyz/entity/cbp-p300-interacting-transactivator-with-glu-asp-rich-carboxy-terminal-domain-2 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/cbp-p300-interacting-transactivator-with-glu-asp-rich-carboxy-terminal-domain-2 · Last refreshed: May 3, 2026