C-X3-C motif chemokine ligand 1

mammalian protein found in Rattus norvegicus

Protein protein Q28556332

Press Enter · cited answer in seconds

C-X3-C motif chemokine ligand 1

Summary

C-X3-C motif chemokine ligand 1 is a protein^[1].

Key Facts

C-X3-C motif chemokine ligand 1's instance of is recorded as protein^[2].
C-X3-C motif chemokine ligand 1's UniProt protein ID is recorded as O55145^[3].
C-X3-C motif chemokine ligand 1's part of is recorded as Chemokine interleukin-8-like superfamily^[4].
C-X3-C motif chemokine ligand 1's part of is recorded as fractalkine^[5].
C-X3-C motif chemokine ligand 1's part of is recorded as membrane protein^[6].
C-X3-C motif chemokine ligand 1's part of is recorded as Chemokine interleukin-8-like domain, protein family^[7].
C-X3-C motif chemokine ligand 1's part of is recorded as CX3C chemokine domain, protein family^[8].
C-X3-C motif chemokine ligand 1's has part is recorded as Chemokine interleukin-8-like domain^[9].
C-X3-C motif chemokine ligand 1's has part is recorded as CX3C chemokine domain^[10].
C-X3-C motif chemokine ligand 1's RefSeq protein ID is recorded as NP_604450^[11].
C-X3-C motif chemokine ligand 1's RefSeq protein ID is recorded as XP_008770551^[12].
C-X3-C motif chemokine ligand 1's molecular function is recorded as cytokine activity^[13].
C-X3-C motif chemokine ligand 1's molecular function is recorded as integrin binding^[14].
C-X3-C motif chemokine ligand 1's molecular function is recorded as chemokine activity^[15].
C-X3-C motif chemokine ligand 1's molecular function is recorded as CX3C chemokine receptor binding^[16].
C-X3-C motif chemokine ligand 1's molecular function is recorded as CCR chemokine receptor binding^[17].
C-X3-C motif chemokine ligand 1's cell component is recorded as extracellular region^[18].
C-X3-C motif chemokine ligand 1's cell component is recorded as extracellular space^[19].
C-X3-C motif chemokine ligand 1's cell component is recorded as cytoplasm^[20].
C-X3-C motif chemokine ligand 1's cell component is recorded as plasma membrane^[21].
C-X3-C motif chemokine ligand 1's cell component is recorded as membrane^[22].
C-X3-C motif chemokine ligand 1's cell component is recorded as integral component of membrane^[23].
C-X3-C motif chemokine ligand 1's cell component is recorded as cell projection^[24].
C-X3-C motif chemokine ligand 1's cell component is recorded as neuron projection^[25].
C-X3-C motif chemokine ligand 1's cell component is recorded as soma^[26].

⭐ Popularity Graph

0/100 long tail

Quick Facts

Instance of protein

Part of Chemokine interleukin-8-like superfamily, fractalkine, membrane protein, Chemokine interleukin-8-like domain, protein family, CX3C chemokine domain, protein family

Properties

Biological process response to hypoxia, microglial cell activation, positive regulation of neuroblast proliferation, leukocyte migration involved in inflammatory response, monocyte chemotaxis, response to ischemia, chemotaxis, inflammatory response, immune response, cell adhesion, G protein-coupled receptor signaling pathway, ageing, regulation of signaling receptor activity, positive regulation of macrophage chemotaxis, positive regulation of neuron projection development, cytokine-mediated signaling pathway, platelet activation, positive regulation of cell migration, neutrophil chemotaxis, negative regulation of interleukin-1 alpha production, integrin activation, autocrine signaling, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of GTPase activity, positive regulation of cell adhesion, negative regulation of vasoconstriction, positive regulation of transcription by RNA polymerase II, eosinophil chemotaxis, lymphocyte chemotaxis, positive regulation of smooth muscle cell proliferation, leukocyte adhesive activation, positive regulation of protein kinase B signaling, inhibitory postsynaptic potential, cell chemotaxis, neuron cellular homeostasis, chemokine-mediated signaling pathway, positive regulation of ERK1 and ERK2 cascade, cellular response to interferon-gamma, cellular response to interleukin-1, cellular response to tumor necrosis factor, cell-cell adhesion, negative regulation of glutamate receptor signaling pathway, negative regulation of microglial cell activation

Cell component extracellular region, extracellular space, cytoplasm, plasma membrane, membrane, integral component of membrane, cell projection, neuron projection, soma, perinuclear region of cytoplasm, postsynapse

Encoded by Cx3cl1

Found in taxon brown rat

Has part(s) Chemokine interleukin-8-like domain, CX3C chemokine domain

Imported from wholeness_audit_2026-05-02

Molecular function cytokine activity, integrin binding, chemokine activity, CX3C chemokine receptor binding, CCR chemokine receptor binding

External References (3)

Ensembl protein id ENSRNOP00000022128, ENSRNOP00000077452

Refseq protein id NP_604450, XP_008770551

Uniprot protein id O55145

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ C-X3-C motif chemokine ligand 1 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ C-X3-C motif chemokine ligand 1 — UniProt protein ID (P352): O55145. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ C-X3-C motif chemokine ligand 1 — part of (P361): Chemokine interleukin-8-like superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ C-X3-C motif chemokine ligand 1 — part of (P361): fractalkine. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ C-X3-C motif chemokine ligand 1 — part of (P361): membrane protein. wikidata.org.
[7] ↑ C-X3-C motif chemokine ligand 1 — part of (P361): Chemokine interleukin-8-like domain, protein family. wikidata.org.
[8] ↑ C-X3-C motif chemokine ligand 1 — part of (P361): CX3C chemokine domain, protein family. wikidata.org.
[9] ↑ C-X3-C motif chemokine ligand 1 — has part(s) (P527): Chemokine interleukin-8-like domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ C-X3-C motif chemokine ligand 1 — has part(s) (P527): CX3C chemokine domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ C-X3-C motif chemokine ligand 1 — RefSeq protein ID (P637): NP_604450. Q20641742. Retrieved 2022-03-20. wikidata.org.
[12] ↑ C-X3-C motif chemokine ligand 1 — RefSeq protein ID (P637): XP_008770551. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ C-X3-C motif chemokine ligand 1 — molecular function (P680): cytokine activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ C-X3-C motif chemokine ligand 1 — molecular function (P680): integrin binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ C-X3-C motif chemokine ligand 1 — molecular function (P680): chemokine activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ C-X3-C motif chemokine ligand 1 — molecular function (P680): CX3C chemokine receptor binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ C-X3-C motif chemokine ligand 1 — molecular function (P680): CCR chemokine receptor binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ C-X3-C motif chemokine ligand 1 — cell component (P681): extracellular region. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ C-X3-C motif chemokine ligand 1 — cell component (P681): extracellular space. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ C-X3-C motif chemokine ligand 1 — cell component (P681): cytoplasm. Fractalkine/CX3CL1 enhances GABA synaptic activity at serotonin neurons in the rat dorsal raphe nucleus. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ C-X3-C motif chemokine ligand 1 — cell component (P681): plasma membrane. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ C-X3-C motif chemokine ligand 1 — cell component (P681): membrane. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ C-X3-C motif chemokine ligand 1 — cell component (P681): integral component of membrane. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ C-X3-C motif chemokine ligand 1 — cell component (P681): cell projection. Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ C-X3-C motif chemokine ligand 1 — cell component (P681): neuron projection. Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ C-X3-C motif chemokine ligand 1 — cell component (P681): soma. Expression of fractalkine and its receptor, CX3CR1, in response to ischaemia-reperfusion brain injury in the rat.. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ C-X3-C motif chemokine ligand 1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). C-X3-C motif chemokine ligand 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/c-x3-c-motif-chemokine-ligand-1-q28556332

MLA

“C-X3-C motif chemokine ligand 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/c-x3-c-motif-chemokine-ligand-1-q28556332.

BibTeX

@misc{4ortxyz_c-x3-c-motif-chemokine-ligand-1-q28556332_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{C-X3-C motif chemokine ligand 1}}, year = {2026}, url = {https://4ort.xyz/entity/c-x3-c-motif-chemokine-ligand-1-q28556332}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): C-X3-C motif chemokine ligand 1 — https://4ort.xyz/entity/c-x3-c-motif-chemokine-ligand-1-q28556332 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/c-x3-c-motif-chemokine-ligand-1-q28556332 · Last refreshed: May 3, 2026