Breast cancer 1, early onset

mammalian protein found in Mus musculus

Protein protein Q14862232

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Breast cancer 1, early onset

Summary

Breast cancer 1, early onset is a protein^[1].

Key Facts

Breast cancer 1, early onset's instance of is recorded as protein^[2].
Breast cancer 1, early onset's subclass of is recorded as protein^[3].
Breast cancer 1, early onset's UniProt protein ID is recorded as P48754^[4].
Breast cancer 1, early onset's part of is recorded as BRCT domain superfamily^[5].
Breast cancer 1, early onset's part of is recorded as Breast cancer type 1 susceptibility protein (BRCA1)^[6].
Breast cancer 1, early onset's part of is recorded as Zinc finger, RING/FYVE/PHD-type^[7].
Breast cancer 1, early onset's part of is recorded as BRCA1, serine-rich domain, protein family^[8].
Breast cancer 1, early onset's part of is recorded as Zinc finger, RING-type, protein family^[9].
Breast cancer 1, early onset's part of is recorded as Zinc finger, C3HC4 RING-type, protein family^[10].
Breast cancer 1, early onset's part of is recorded as BRCT domain, protein family^[11].
Breast cancer 1, early onset's part of is recorded as Zinc finger, RING-type, conserved site, protein family^[12].
Breast cancer 1, early onset's has part is recorded as Zinc finger, RING-type, conserved site^[13].
Breast cancer 1, early onset's has part is recorded as Zinc finger, RING-type^[14].
Breast cancer 1, early onset's has part is recorded as BRCT domain^[15].
Breast cancer 1, early onset's has part is recorded as Zinc finger, C3HC4 RING-type^[16].
Breast cancer 1, early onset's has part is recorded as BRCA1, serine-rich domain^[17].
Breast cancer 1, early onset's RefSeq protein ID is recorded as NP_033894^[18].
Breast cancer 1, early onset's RefSeq protein ID is recorded as XP_006532127^[19].
Breast cancer 1, early onset's RefSeq protein ID is recorded as XP_006532131^[20].
Breast cancer 1, early onset's RefSeq protein ID is recorded as XP_030101355^[21].
Breast cancer 1, early onset's RefSeq protein ID is recorded as XP_036012146^[22].
Breast cancer 1, early onset's molecular function is recorded as metal ion binding^[23].
Breast cancer 1, early onset's molecular function is recorded as enzyme binding^[24].
Breast cancer 1, early onset's molecular function is recorded as zinc ion binding^[25].
Breast cancer 1, early onset's molecular function is recorded as damaged DNA binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of BRCT domain superfamily, Breast cancer type 1 susceptibility protein (BRCA1), Zinc finger, RING/FYVE/PHD-type, BRCA1, serine-rich domain, protein family, Zinc finger, RING-type, protein family, Zinc finger, C3HC4 RING-type, protein family, BRCT domain, protein family, Zinc finger, RING-type, conserved site, protein family

Properties

Biological process response to ionizing radiation, centrosome cycle, chromosome segregation, cellular response to DNA damage stimulus, protein K6-linked ubiquitination, intrinsic apoptotic signaling pathway in response to DNA damage, cell cycle, regulation of gene expression by genetic imprinting, regulation of transcription, DNA-templated, negative regulation of fatty acid biosynthetic process, positive regulation of histone H3-K9 acetylation, transcription, DNA-templated, positive regulation of transcription, DNA-templated, fatty acid biosynthetic process, positive regulation of histone H3-K4 methylation, double-strand break repair via homologous recombination, protein ubiquitination, regulation of DNA methylation, negative regulation of intracellular estrogen receptor signaling pathway, DNA repair, protein autoubiquitination, positive regulation of histone H3-K9 methylation, DNA recombination, centrosome duplication, positive regulation of angiogenesis, response to estrogen, cellular response to indole-3-methanol, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, negative regulation of transcription, DNA-templated, positive regulation of protein ubiquitination, chordate embryonic development, postreplication repair, lipid metabolism, cellular response to tumor necrosis factor, positive regulation of DNA repair, fatty acid metabolic process, positive regulation of histone acetylation, positive regulation of gene expression, negative regulation of histone H3-K4 methylation, regulation of cell population proliferation, double-strand break repair, negative regulation of histone H3-K9 methylation, negative regulation of reactive oxygen species metabolic process, positive regulation of vascular endothelial growth factor production, positive regulation of histone H4-K20 methylation, dosage compensation by inactivation of X chromosome, negative regulation of histone acetylation, positive regulation of transcription by RNA polymerase II, positive regulation of histone H4-K16 acetylation, mitotic G2/M transition checkpoint, regulation of transcription by RNA polymerase II, transcription by RNA polymerase II, mitotic G2 DNA damage checkpoint signaling, dosage compensation by inactivation of X chromosome, positive regulation of histone acetylation, negative regulation of histone acetylation, chordate embryonic development, positive regulation of transcription by RNA polymerase II

Cell component cytoplasm, BRCA1-BARD1 complex, condensed nuclear chromosome, nucleus, centrosome, BRCA1-A complex, plasma membrane, chromosome, nucleoplasm, condensed chromosome, lateral element, protein-containing complex, mitochondrial matrix, ribonucleoprotein complex

Encoded by Brca1

Found in taxon house mouse

Has part(s) Zinc finger, RING-type, conserved site, Zinc finger, RING-type, BRCT domain, Zinc finger, C3HC4 RING-type, BRCA1, serine-rich domain

Imported from wholeness_audit_2026-05-02

Molecular function metal ion binding, enzyme binding, zinc ion binding, damaged DNA binding, DNA binding, ubiquitin-protein transferase activity, RNA binding, ubiquitin protein ligase binding, transferase activity, transcription coactivator activity, RNA polymerase binding, chromatin binding, transcription coactivator activity, identical protein binding, identical protein binding

External References (3)

Ensembl protein id ENSMUSP00000017290, ENSMUSP00000139599, ENSMUSP00000139737, ENSMUSP00000139813

Refseq protein id NP_033894, XP_006532127, XP_006532131, XP_030101355, XP_036012146

Uniprot protein id P48754

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Breast cancer 1, early onset — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Breast cancer 1, early onset — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Breast cancer 1, early onset — UniProt protein ID (P352): P48754. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Breast cancer 1, early onset — part of (P361): BRCT domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Breast cancer 1, early onset — part of (P361): Breast cancer type 1 susceptibility protein (BRCA1). InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Breast cancer 1, early onset — part of (P361): Zinc finger, RING/FYVE/PHD-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Breast cancer 1, early onset — part of (P361): BRCA1, serine-rich domain, protein family. wikidata.org.
[9] ↑ Breast cancer 1, early onset — part of (P361): Zinc finger, RING-type, protein family. wikidata.org.
[10] ↑ Breast cancer 1, early onset — part of (P361): Zinc finger, C3HC4 RING-type, protein family. wikidata.org.
[11] ↑ Breast cancer 1, early onset — part of (P361): BRCT domain, protein family. wikidata.org.
[12] ↑ Breast cancer 1, early onset — part of (P361): Zinc finger, RING-type, conserved site, protein family. wikidata.org.
[13] ↑ Breast cancer 1, early onset — has part(s) (P527): Zinc finger, RING-type, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Breast cancer 1, early onset — has part(s) (P527): Zinc finger, RING-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Breast cancer 1, early onset — has part(s) (P527): BRCT domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Breast cancer 1, early onset — has part(s) (P527): Zinc finger, C3HC4 RING-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Breast cancer 1, early onset — has part(s) (P527): BRCA1, serine-rich domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Breast cancer 1, early onset — RefSeq protein ID (P637): NP_033894. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ Breast cancer 1, early onset — RefSeq protein ID (P637): XP_006532127. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Breast cancer 1, early onset — RefSeq protein ID (P637): XP_006532131. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ Breast cancer 1, early onset — RefSeq protein ID (P637): XP_030101355. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Breast cancer 1, early onset — RefSeq protein ID (P637): XP_036012146. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Breast cancer 1, early onset — molecular function (P680): metal ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Breast cancer 1, early onset — molecular function (P680): enzyme binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Breast cancer 1, early onset — molecular function (P680): zinc ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Breast cancer 1, early onset — molecular function (P680): damaged DNA binding. Genomic instability in mice lacking histone H2AX. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Breast cancer 1, early onset is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Breast cancer 1, early onset. Retrieved May 3, 2026, from https://4ort.xyz/entity/breast-cancer-1-early-onset

MLA

“Breast cancer 1, early onset.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/breast-cancer-1-early-onset.

BibTeX

@misc{4ortxyz_breast-cancer-1-early-onset_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Breast cancer 1, early onset}}, year = {2026}, url = {https://4ort.xyz/entity/breast-cancer-1-early-onset}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Breast cancer 1, early onset — https://4ort.xyz/entity/breast-cancer-1-early-onset (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/breast-cancer-1-early-onset · Last refreshed: May 3, 2026