BRCA1, DNA repair associated

mammalian protein found in Rattus norvegicus

Protein protein Q28561770

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BRCA1, DNA repair associated

Summary

BRCA1, DNA repair associated is a protein^[1].

Key Facts

BRCA1, DNA repair associated's instance of is recorded as protein^[2].
BRCA1, DNA repair associated's subclass of is recorded as protein^[3].
BRCA1, DNA repair associated's UniProt protein ID is recorded as O54952^[4].
BRCA1, DNA repair associated's part of is recorded as BRCT domain superfamily^[5].
BRCA1, DNA repair associated's part of is recorded as Breast cancer type 1 susceptibility protein (BRCA1)^[6].
BRCA1, DNA repair associated's part of is recorded as Zinc finger, RING/FYVE/PHD-type^[7].
BRCA1, DNA repair associated's part of is recorded as BRCA1, serine-rich domain, protein family^[8].
BRCA1, DNA repair associated's part of is recorded as Zinc finger, RING-type, protein family^[9].
BRCA1, DNA repair associated's part of is recorded as Zinc finger, C3HC4 RING-type, protein family^[10].
BRCA1, DNA repair associated's part of is recorded as BRCT domain, protein family^[11].
BRCA1, DNA repair associated's part of is recorded as Zinc finger, RING-type, conserved site, protein family^[12].
BRCA1, DNA repair associated's has part is recorded as Zinc finger, C3HC4 RING-type^[13].
BRCA1, DNA repair associated's has part is recorded as Zinc finger, RING-type, conserved site^[14].
BRCA1, DNA repair associated's has part is recorded as Zinc finger, RING-type^[15].
BRCA1, DNA repair associated's has part is recorded as BRCA1, serine-rich domain^[16].
BRCA1, DNA repair associated's has part is recorded as BRCT domain^[17].
BRCA1, DNA repair associated's RefSeq protein ID is recorded as NP_036646^[18].
BRCA1, DNA repair associated's RefSeq protein ID is recorded as XP_008766314^[19].
BRCA1, DNA repair associated's RefSeq protein ID is recorded as XP_038942469^[20].
BRCA1, DNA repair associated's RefSeq protein ID is recorded as XP_038942470^[21].
BRCA1, DNA repair associated's molecular function is recorded as DNA binding^[22].
BRCA1, DNA repair associated's molecular function is recorded as chromatin binding^[23].
BRCA1, DNA repair associated's molecular function is recorded as transcription coactivator activity^[24].
BRCA1, DNA repair associated's molecular function is recorded as ubiquitin-protein transferase activity^[25].
BRCA1, DNA repair associated's molecular function is recorded as protein binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of BRCT domain superfamily, Breast cancer type 1 susceptibility protein (BRCA1), Zinc finger, RING/FYVE/PHD-type, BRCA1, serine-rich domain, protein family, Zinc finger, RING-type, protein family, Zinc finger, C3HC4 RING-type, protein family, BRCT domain, protein family, Zinc finger, RING-type, conserved site, protein family

Properties

Biological process double-strand break repair via homologous recombination, DNA repair, DNA recombination, regulation of transcription by RNA polymerase II, lipid metabolism, fatty acid metabolic process, fatty acid biosynthetic process, cellular response to DNA damage stimulus, cell cycle, brain development, response to nutrient, dosage compensation by inactivation of X chromosome, response to organic substance, protein ubiquitination, response to estradiol, response to lipid, positive regulation of histone acetylation, negative regulation of histone acetylation, chordate embryonic development, negative regulation of fatty acid biosynthetic process, positive regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, protein autoubiquitination, protein K6-linked ubiquitination

Cell component nucleus, chromosome, cytoplasm, mitochondrial matrix, plasma membrane, BRCA1-BARD1 complex, BRCA1-A complex

Encoded by Brca1

Found in taxon brown rat

Has part(s) Zinc finger, C3HC4 RING-type, Zinc finger, RING-type, conserved site, Zinc finger, RING-type, BRCA1, serine-rich domain, BRCT domain

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, chromatin binding, transcription coactivator activity, ubiquitin-protein transferase activity, protein binding, zinc ion binding, transferase activity, metal ion binding, RNA polymerase binding

External References (3)

Ensembl protein id ENSRNOP00000028109, ENSRNOP00000072366

Refseq protein id NP_036646, XP_008766314, XP_038942469, XP_038942470

Uniprot protein id O54952

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ BRCA1, DNA repair associated — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ BRCA1, DNA repair associated — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ BRCA1, DNA repair associated — UniProt protein ID (P352): O54952. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ BRCA1, DNA repair associated — part of (P361): BRCT domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ BRCA1, DNA repair associated — part of (P361): Breast cancer type 1 susceptibility protein (BRCA1). InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ BRCA1, DNA repair associated — part of (P361): Zinc finger, RING/FYVE/PHD-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ BRCA1, DNA repair associated — part of (P361): BRCA1, serine-rich domain, protein family. wikidata.org.
[9] ↑ BRCA1, DNA repair associated — part of (P361): Zinc finger, RING-type, protein family. wikidata.org.
[10] ↑ BRCA1, DNA repair associated — part of (P361): Zinc finger, C3HC4 RING-type, protein family. wikidata.org.
[11] ↑ BRCA1, DNA repair associated — part of (P361): BRCT domain, protein family. wikidata.org.
[12] ↑ BRCA1, DNA repair associated — part of (P361): Zinc finger, RING-type, conserved site, protein family. wikidata.org.
[13] ↑ BRCA1, DNA repair associated — has part(s) (P527): Zinc finger, C3HC4 RING-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ BRCA1, DNA repair associated — has part(s) (P527): Zinc finger, RING-type, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ BRCA1, DNA repair associated — has part(s) (P527): Zinc finger, RING-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ BRCA1, DNA repair associated — has part(s) (P527): BRCA1, serine-rich domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ BRCA1, DNA repair associated — has part(s) (P527): BRCT domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ BRCA1, DNA repair associated — RefSeq protein ID (P637): NP_036646. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ BRCA1, DNA repair associated — RefSeq protein ID (P637): XP_008766314. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ BRCA1, DNA repair associated — RefSeq protein ID (P637): XP_038942469. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ BRCA1, DNA repair associated — RefSeq protein ID (P637): XP_038942470. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ BRCA1, DNA repair associated — molecular function (P680): DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ BRCA1, DNA repair associated — molecular function (P680): chromatin binding. Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ BRCA1, DNA repair associated — molecular function (P680): transcription coactivator activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ BRCA1, DNA repair associated — molecular function (P680): ubiquitin-protein transferase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ BRCA1, DNA repair associated — molecular function (P680): protein binding. Prolactin blocks nuclear translocation of VDR by regulating its interaction with BRCA1 in osteosarcoma cells. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ BRCA1, DNA repair associated is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). BRCA1, DNA repair associated. Retrieved May 3, 2026, from https://4ort.xyz/entity/brca1-dna-repair-associated-q28561770

MLA

“BRCA1, DNA repair associated.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/brca1-dna-repair-associated-q28561770.

BibTeX

@misc{4ortxyz_brca1-dna-repair-associated-q28561770_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{BRCA1, DNA repair associated}}, year = {2026}, url = {https://4ort.xyz/entity/brca1-dna-repair-associated-q28561770}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): BRCA1, DNA repair associated — https://4ort.xyz/entity/brca1-dna-repair-associated-q28561770 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/brca1-dna-repair-associated-q28561770 · Last refreshed: May 3, 2026