APOC1

protein-coding gene in the species Homo sapiens
Gene gene Q14904550
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APOC1

Summary

APOC1 is a gene[1]. APOC1 ranks in the top 2% of gene entities by monthly Wikipedia readership (4 views/month).[2]

Key Facts

  • APOC1's instance of is recorded as gene[3].
  • APOC1 is a type of protein-coding gene[4].
  • APOC1's HomoloGene ID is recorded as 136749[5].
  • APOC1's genomic start is recorded as 44914247[6].
  • APOC1's genomic start is recorded as 45417504[7].
  • APOC1's genomic end is recorded as 44919349[8].
  • APOC1's genomic end is recorded as 45422606[9].
  • APOC1's molecular function is recorded as phospholipase inhibitor activity[10].
  • APOC1's molecular function is recorded as fatty acid binding[11].
  • APOC1's molecular function is recorded as phosphatidylcholine binding[12].
  • APOC1's molecular function is recorded as lipase inhibitor activity[13].
  • APOC1's molecular function is recorded as phosphatidylcholine-sterol O-acyltransferase activator activity[14].
  • APOC1's cell component is recorded as extracellular region[15].
  • APOC1's cell component is recorded as endoplasmic reticulum[16].
  • APOC1's cell component is recorded as very-low-density lipoprotein particle[17].
  • APOC1's cell component is recorded as high-density lipoprotein particle[18].
  • APOC1's cell component is recorded as chylomicron[19].
  • APOC1's cell component is recorded as extracellular exosome[20].
  • APOC1's biological process is recorded as lipid metabolism[21].
  • APOC1's biological process is recorded as triglyceride metabolic process[22].
  • APOC1's biological process is recorded as transport[23].
  • APOC1's biological process is recorded as lipid transport[24].
  • APOC1's biological process is recorded as cholesterol metabolic process[25].
  • APOC1's biological process is recorded as positive regulation of cholesterol esterification[26].
  • APOC1's biological process is recorded as negative regulation of phosphatidylcholine catabolic process[27].

Why It Matters

APOC1 ranks in the top 2% of gene entities by monthly Wikipedia readership (4 views/month).[2] APOC1 has Wikipedia articles in 6 language editions, a strong signal of global cultural recognition.[28] APOC1 is known by 6 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . ensembl Release 106. wikidata.org.
  2. [4] . Ensembl Release 87. wikidata.org.
  3. [5] . Q20641742. Retrieved . wikidata.org.
  4. [6] . ensembl Release 106. wikidata.org.
  5. [7] . ensembl Release 106. wikidata.org.
  6. [8] . ensembl Release 106. wikidata.org.
  7. [9] . ensembl Release 106. wikidata.org.
  8. [10] . Apolipoprotein C-1 inhibits the hydrolysis by phospholipase A2 of phospholipids in liposomes and cell membranes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] . Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . Apolipoprotein C-1 inhibits the hydrolysis by phospholipase A2 of phospholipids in liposomes and cell membranes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . Exact localization of the familial dysbetalipoproteinemia associated HpaI restriction site in the promoter region of the APOC1 gene. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . Apolipoprotein C-1 inhibits the hydrolysis by phospholipase A2 of phospholipids in liposomes and cell membranes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). APOC1. Retrieved May 3, 2026, from https://4ort.xyz/entity/apoc1
MLA “APOC1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/apoc1.
BibTeX @misc{4ortxyz_apoc1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{APOC1}}, year = {2026}, url = {https://4ort.xyz/entity/apoc1}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): APOC1 — https://4ort.xyz/entity/apoc1 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/apoc1 · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 1d ago · Mathieu Kappler · 2026-05-20 view diff on Wikidata ↗
    Genetic association Alzheimer's disease
    Biological process lipid metabolism, triglyceride metabolic process, transport +21
    Subclass of
    Cell component extracellular region, endoplasmic reticulum, very-low-density lipoprotein particle +3
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||gsw */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/32527|batch #32527]]: human gene name and description in Alemannic"
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