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Tumor suppressor ARF

human protein (annotated by UniProtKB/Swiss-Prot Q8N726)
Protein protein Q7117832
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Tumor suppressor ARF

Summary

Tumor suppressor ARF is a protein[1]. It draws 5 Wikipedia views per month (protein category, ranking #151 of 987).[2]

Key Facts

  • Tumor suppressor ARF's instance of is recorded as protein[3].
  • Tumor suppressor ARF's UniProt protein ID is recorded as Q8N726[4].
  • Tumor suppressor ARF's part of is recorded as tumor suppressor ARF[5].
  • Tumor suppressor ARF's RefSeq protein ID is recorded as NP_478102.2[6].
  • Tumor suppressor ARF's PDB structure ID is recorded as 1A5E[7].
  • Tumor suppressor ARF's PDB structure ID is recorded as 1BI7[8].
  • Tumor suppressor ARF's PDB structure ID is recorded as 1DC2[9].
  • Tumor suppressor ARF's PDB structure ID is recorded as 2A5E[10].
  • Tumor suppressor ARF's molecular function is recorded as DNA binding[11].
  • Tumor suppressor ARF's molecular function is recorded as p53 binding[12].
  • Tumor suppressor ARF's molecular function is recorded as transcription factor binding[13].
  • Tumor suppressor ARF's molecular function is recorded as MDM2/MDM4 family protein binding[14].
  • Tumor suppressor ARF's molecular function is recorded as ubiquitin-protein transferase inhibitor activity[15].
  • Tumor suppressor ARF's molecular function is recorded as protein binding[16].
  • Tumor suppressor ARF's molecular function is recorded as SUMO transferase activity[17].
  • Tumor suppressor ARF's molecular function is recorded as disordered domain specific binding[18].
  • Tumor suppressor ARF's molecular function is recorded as ubiquitin ligase inhibitor activity[19].
  • Tumor suppressor ARF's cell component is recorded as nuclear body[20].
  • Tumor suppressor ARF's cell component is recorded as nucleoplasm[21].
  • Tumor suppressor ARF's cell component is recorded as nucleolus[22].
  • Tumor suppressor ARF's cell component is recorded as mitochondrion[23].
  • Tumor suppressor ARF's cell component is recorded as nucleus[24].
  • Tumor suppressor ARF's cell component is recorded as protein-containing complex[25].
  • Tumor suppressor ARF's cell component is recorded as mitochondrion[26].
  • Tumor suppressor ARF's biological process is recorded as apoptotic process[27].

Why It Matters

Tumor suppressor ARF draws 5 Wikipedia views per month (protein category, ranking #151 of 987).[2]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . wikidata.org.
  2. [4] ↑ . Q905695. Retrieved . wikidata.org.
  3. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . Q905695. Retrieved . wikidata.org.
  5. [7] ↑ . Swiss-Prot. Retrieved . uniprot.org. Provenance: wikidata.org.
  6. [8] ↑ . Swiss-Prot. Retrieved . uniprot.org. Provenance: wikidata.org.
  7. [9] ↑ . Swiss-Prot. Retrieved . uniprot.org. Provenance: wikidata.org.
  8. [10] ↑ . Swiss-Prot. Retrieved . uniprot.org. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . PTEN regulation by Akt-EGR1-ARF-PTEN axis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . A novel ARF-binding protein (LZAP) alters ARF regulation of HDM2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . Tumor suppressor ARF promotes non-classic proteasome-independent polyubiquitination of COMMD1. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . p14 Arf promotes small ubiquitin-like modifier conjugation of Werners helicase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . Peptides derived from two dynamically disordered proteins self-assemble into amyloid-like fibrils. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Short Mitochondrial ARF Triggers Parkin/PINK1-dependent Mitophagy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Tumor suppressor ARF. Retrieved May 3, 2026, from https://4ort.xyz/entity/tumor-suppressor-arf
MLA “Tumor suppressor ARF.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/tumor-suppressor-arf.
BibTeX @misc{4ortxyz_tumor-suppressor-arf_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Tumor suppressor ARF}}, year = {2026}, url = {https://4ort.xyz/entity/tumor-suppressor-arf}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Tumor suppressor ARF — https://4ort.xyz/entity/tumor-suppressor-arf (retrieved 2026-05-03)

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