# Zinc metallopeptidase, STE24

> mammalian protein found in Mus musculus

**Wikidata**: [Q21497801](https://www.wikidata.org/wiki/Q21497801)  
**Source**: https://4ort.xyz/entity/zinc-metallopeptidase-ste24-q21497801


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q80W54)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
5. [Biochemical studies of Zmpste24-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80W54&geneProductId=UniProtKB:Q80W54)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80W54&geneProductId=UniProtKB:Q80W54)
7. [Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
8. [HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
9. [Biochemical studies of Zmpste24-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
11. [Genomic instability in laminopathy-based premature aging](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
12. [ZMPSTE24 defends against influenza and other pathogenic viruses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
13. [Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
14. [Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
15. [Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
16. [Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
17. [Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
18. [Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
19. [Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
20. [Prelamin A and lamin A appear to be dispensable in the nuclear lamina](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
21. [Premature aging in mice activates a systemic metabolic response involving autophagy induction.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
22. [Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
23. [Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
24. [Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W54)
25. ensembl Release 106