# Yes1 associated transcriptional regulator

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109257](https://www.wikidata.org/wiki/Q21109257)  
**Source**: https://4ort.xyz/entity/yes1-associated-transcriptional-regulator


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P46937)
3. Q20641742
4. [Tumor suppressor LATS1 is a negative regulator of oncogene YAP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
5. [TEAD mediates YAP-dependent gene induction and growth control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
6. [PTPN14 interacts with and negatively regulates the oncogenic function of YAP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
7. [Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
8. [Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
9. [Angiomotin-like proteins associate with and negatively regulate YAP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
10. [PTPN14 is required for the density-dependent control of YAP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
11. [The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
12. [Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
13. [Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
14. [Proline-rich Gla protein 2 is a cell-surface vitamin K-dependent protein that binds to the transcriptional coactivator Yes-associated protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
15. [Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
16. [Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
17. [Yap1 acts downstream of α-catenin to control epidermal proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
18. [A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
19. [Structural and functional analysis of the YAP-binding domain of human TEAD2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
20. [β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
21. [Ligand binding to WW tandem domains of YAP2 transcriptional regulator is under negative cooperativity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
22. [Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
23. [Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
24. [Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
25. [Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
26. [Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
27. [Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
28. [AMPK modulates Hippo pathway activity to regulate energy homeostasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
29. [MEK1 promotes YAP and their interaction is critical for tumorigenesis in liver cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
30. [A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
31. [Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
32. [Proteome-wide analysis of phospho-regulated PDZ domain interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
33. [Rab11a promotes proliferation and invasion through regulation of YAP in non-small cell lung cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
34. [Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
35. [YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
36. [Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
37. [Physical interaction with Yes-associated protein enhances p73 transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
38. [A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
39. [Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
40. [Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
41. [14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
42. [Aerobic glycolysis tunes YAP/TAZ transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
43. [Interaction of WW Domains with Hematopoietic Transcription Factor p45/NF-E2 and RNA Polymerase II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
44. [Structural insights into the YAP and TEAD complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
45. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
46. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
47. [Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
48. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46937&geneProductId=UniProtKB:P46937)
49. [Nf2–Yap signaling controls the expansion of DRG progenitors and glia during DRG development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)
50. [WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46937)