# YES proto-oncogene 1, Src family tyrosine kinase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21097216](https://www.wikidata.org/wiki/Q21097216)  
**Source**: https://4ort.xyz/entity/yes-proto-oncogene-1-src-family-tyrosine-kinase


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P07947)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
6. [Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
7. [Cooperation between integrin alphavbeta3 and VEGFR2 in angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07947&geneProductId=UniProtKB:P07947)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07947&geneProductId=UniProtKB:P07947)
9. [Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
10. [VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
11. [The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
12. [Phospho-tyrosine dependent protein-protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
13. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
14. [Analysis of 5-lipoxygenase phosphorylation on molecular level by MALDI-MS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
15. [Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
16. [EG-1 interacts with c-Src and activates its signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
17. [The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motility](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
18. [Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
19. [The Lyn kinase C-lobe mediates Golgi export of Lyn through conformation-dependent ACSL3 association](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
20. [Characterization of cDNA clones for the human c-yes gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
21. [Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
22. [Vav2 is required for cell spreading](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
23. [Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
24. [Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
25. [Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
26. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
27. [Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
28. [Cooperation between integrin alphavbeta3 and VEGFR2 in angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
29. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07947&geneProductId=UniProtKB:P07947)
30. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07947&geneProductId=UniProtKB:P07947)
31. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07947&geneProductId=UniProtKB:P07947)
32. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
33. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947)
34. Ensembl Release 99