# Xrs2p YDR369C

> fungal protein found in Saccharomyces cerevisiae S288c

**Wikidata**: [Q27547391](https://www.wikidata.org/wiki/Q27547391)  
**Source**: https://4ort.xyz/entity/xrs2p-ydr369c


## References

1. UniProt
2. Q20641742
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P33301)
4. [The characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 complex reveals that Rad50 negatively regulates Mre11 endonucleolytic but not the exonucleolytic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
5. [Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
6. [Yeast Xrs2 Binds DNA and Helps Target Rad50 and Mre11 to DNA Ends](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
7. [Structure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
8. [Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
9. [Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
10. [Sae2 promotes dsDNA endonuclease activity within Mre11–Rad50–Xrs2 to resect DNA breaks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
11. [DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
12. [Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
13. [Proteome-wide protein interaction measurements of bacterial proteins of unknown function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
14. [Complex formation and functional versatility of Mre11 of budding yeast in recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
15. [The Rad50 coiled-coil domain is indispensable for Mre11 complex functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
16. [Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
17. [Xrs2p regulates Mre11p translocation to the nucleus and plays a role in telomere elongation and meiotic recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
19. [Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
20. [Mitochondrial Genome Maintenance: Roles for Nuclear Nonhomologous End-Joining Proteins in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
21. [A genomics-based screen for yeast mutants with an altered recombination/end-joining repair ratio.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
22. [A novel function for the Mre11-Rad50-Xrs2 complex in base excision repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
23. [The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide repeat expansions independently of homologous recombination.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33301)
24. ensembl Release 106