# Wnt family member 5A

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21123973](https://www.wikidata.org/wiki/Q21123973)  
**Source**: https://4ort.xyz/entity/wnt-family-member-5a


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P41221)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
5. [SUZ12 is a candidate target of the non‐canonical WNT pathway in the progression of chronic myeloid leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
6. [Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
7. [Wnt5A/CaMKII Signaling Contributes to the Inflammatory Response of Macrophages and Is a Target for the Antiinflammatory Action of Activated Protein C and Interleukin-10](http://www.ebi.ac.uk/QuickGO/annotations?protein=P41221&geneProductId=UniProtKB:P41221)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P41221&geneProductId=UniProtKB:P41221)
9. [Wnt5A/CaMKII Signaling Contributes to the Inflammatory Response of Macrophages and Is a Target for the Antiinflammatory Action of Activated Protein C and Interleukin-10](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
10. [Wnts grasp the WIF domain of Wnt Inhibitory Factor 1 at two distinct binding sites](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
11. [A novel Wnt5a‐Frizzled4 signaling pathway mediates activity‐independent dendrite morphogenesis via the distal PDZ motif of Frizzled 4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
13. [CaSR stimulates secretion of Wnt5a from colonic myofibroblasts to stimulate CDX2 and sucrase-isomaltase using Ror2 on intestinal epithelia](http://www.ebi.ac.uk/QuickGO/annotations?protein=P41221&geneProductId=UniProtKB:P41221)
14. [WNT5A Is Regulated by PAX2 and May Be Involved in Blastemal Predominant Wilms Tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P41221&geneProductId=UniProtKB:P41221)
15. [Expression of Wnt5a in tooth germs and the related signal transduction analysis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P41221&geneProductId=UniProtKB:P41221)
16. [WNT5A Is Regulated by PAX2 and May Be Involved in Blastemal Predominant Wilms Tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
17. [CaSR stimulates secretion of Wnt5a from colonic myofibroblasts to stimulate CDX2 and sucrase-isomaltase using Ror2 on intestinal epithelia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
18. [Expression of Wnt5a in tooth germs and the related signal transduction analysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
19. [Comprehensive proteomic characterization of stem cell-derived extracellular matrices](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
20. [Wnt-5a/Frizzled9 Receptor Signaling through the Gαo-Gβγ Complex Regulates Dendritic Spine Formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
21. [Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
22. [Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
23. [Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
24. [Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
25. [WNT5A mutations in patients with autosomal dominant Robinow syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
26. [WNT5A inhibits human dental papilla cell proliferation and migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
27. [Cooperation Between TGF-β and Wnt Pathways During Chondrocyte and Adipocyte Differentiation of Human Marrow Stromal Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
28. [Wnt5a Exhibits Layer-Specific Expression in Adult Skin, Is Upregulated in Psoriasis, and Synergizes with Type 1 Interferon](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
29. [Role of Wnt-5a in the Determination of Human Mesenchymal Stem Cells into Preadipocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
30. [WNT5A Is a Regulator of Fibroblast Proliferation and Resistance to Apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
31. [Expression patterns of Wnt genes during development of an anterior part of the chicken eye](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
32. [Role of members of the Wnt gene family in human hematopoiesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
33. [Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate](http://www.ebi.ac.uk/QuickGO/annotations?protein=P41221&geneProductId=UniProtKB:P41221)
34. [Developmental Changes in Human Fetal Testicular Cell Numbers and Messenger Ribonucleic Acid Levels during the Second Trimester](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
35. [Wnt5a Signaling Induces Proliferation and Survival of Endothelial Cells In Vitro and Expression of MMP-1 and Tie-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
36. [Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
37. [Wnt5a-mediated non-canonical Wnt signalling regulates human endothelial cell proliferation and migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
38. [RETRACTED ARTICLE: cGMP-phosphodiesterase 6, transducin and Wnt5a/Frizzled-2-signaling control cGMP and Ca2+ homeostasis in melanoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
39. [Downregulation of Wnt4 and upregulation of Wnt5a expression by epithelialmesenchymal transition in human squamous carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
40. [Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
41. [Detecting PKC Phosphorylation as Part of the Wnt/Calcium Pathway in Cutaneous Melanoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
42. [Activation of Wnt5A signaling is required for CXC chemokine ligand 12–mediated T-cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
43. [The importance of Wnt signalling for neurodegeneration in Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
44. [Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P41221&geneProductId=UniProtKB:P41221)
45. [Effects of Grade of Oocyte–Cumulus Complex and the Interactions Between Grades on the Production of Blastocysts in the Cow, Ewe and Lamb](http://www.ebi.ac.uk/QuickGO/annotations?protein=P41221&geneProductId=UniProtKB:P41221)
46. [Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
47. [WNT5A Signaling Contributes to Aβ-Induced Neuroinflammation and Neurotoxicity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
48. [Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41221)
49. Ensembl Release 99