# Wnt family member 3A

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21115939](https://www.wikidata.org/wiki/Q21115939)  
**Source**: https://4ort.xyz/entity/wnt-family-member-3a


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P56704)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
5. [Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
7. [WLS retrograde transport to the endoplasmic reticulum during Wnt secretion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
8. [Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
9. [Wnt antagonists bind through a short peptide to the first β-propeller domain of LRP5/6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
10. [Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
11. [APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
12. [Tiki1 Is Required for Head Formation via Wnt Cleavage-Oxidation and Inactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P56704&geneProductId=UniProtKB:P56704)
14. [Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
15. [Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
16. [Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
17. [Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
18. [The Hippo pathway regulates Wnt/beta-catenin signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
19. [Helicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
20. [Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
21. [Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
22. [Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
23. [The importance of Wnt signalling for neurodegeneration in Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
24. [SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
25. [Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
26. [The microRNA-29 family in cartilage homeostasis and osteoarthritis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
27. [Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
28. [Soluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
29. [Wnk kinases are positive regulators of canonical Wnt/β-catenin signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
30. [beta-catenin is involved in N-cadherin-dependent adhesion, but not in canonical Wnt signaling in E2A-PBX1-positive B acute lymphoblastic leukemia cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
31. [Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
32. [Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56704)
33. Ensembl Release 99
34. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)
35. UMLS 2023