# Wnt family member 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21123961](https://www.wikidata.org/wiki/Q21123961)  
**Source**: https://4ort.xyz/entity/wnt-family-member-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P04628)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
5. [Uncovering novel actors in astrocyte–neuron crosstalk in Parkinson's disease: the Wnt/β‐catenin signaling cascade as the common final pathway for neuroprotection and self‐repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
6. [The effect on cell growth by Wnt1 RNAi in human neuroblastoma SH-SY5Y cell line](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
8. [Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
9. [Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
10. [Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
11. [Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumours](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
12. [Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
13. [A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
14. [Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
15. [SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
16. [BMP-2-modulated chondrogenic differentiation in vitro involves down-regulation of membrane-bound beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
17. [Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04628&geneProductId=UniProtKB:P04628)
18. [SUZ12 is a candidate target of the non-canonical WNT pathway in the progression of chronic myeloid leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
19. [Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
20. [Stem cell markers in the human posterior limbus and corneal endothelium of unwounded and wounded corneas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
21. [Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
22. [Mutations in WNT1 cause different forms of bone fragility](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
23. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04628&geneProductId=UniProtKB:P04628)
24. [Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04628&geneProductId=UniProtKB:P04628)
25. [The importance of Wnt signalling for neurodegeneration in Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
26. [A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1(+/-) mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04628)
27. Ensembl Release 99