# Wingless Dmel_CG4889

> protein found in Drosophila melanogaster

**Wikidata**: [Q29812690](https://www.wikidata.org/wiki/Q29812690)  
**Source**: https://4ort.xyz/entity/wingless-dmel-cg4889


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P09615)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
5. [Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
6. [Ligand receptor interactions in the Wnt signaling pathway in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
7. [Roles of N-glycosylation and lipidation in Wg secretion and signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
8. [A new member of the frizzled family from Drosophila functions as a Wingless receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
10. [Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
11. [Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
12. [Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
13. [p24 proteins are required for secretion of Wnt ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
14. [Roles of N-glycosylation and lipidation in Wg secretion and signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
15. [Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
16. [Carrier of Wingless (Cow), a secreted heparan sulfate proteoglycan, promotes extracellular transport of Wingless.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
17. [Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
18. [The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
19. [A new member of the frizzled family from Drosophila functions as a Wingless receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
20. [Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
21. [Direct and long-range action of a wingless morphogen gradient](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
22. [Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
23. [Ligand receptor interactions in the Wnt signaling pathway in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
24. [Sulfated is a negative feedback regulator of wingless in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
25. [The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
26. [Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
27. [Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
28. [Carrier of Wingless (Cow), a secreted heparan sulfate proteoglycan, promotes extracellular transport of Wingless.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
29. [Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
30. [Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09615&geneProductId=UniProtKB:P09615)
31. [Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
32. [In vivo role of lipid adducts on Wingless](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
33. [Fragile X mental retardation protein regulates trans-synaptic signaling inDrosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
34. [Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
35. [A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
36. [Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
37. [Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
38. [Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
39. [Sulfated is a negative feedback regulator of wingless in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
40. [Patterning the peripheral retina of the fly: decoding a gradient](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
41. [Analysis of micro- and nano-structures of the corneal surface of Drosophila and its mutants by atomic force microscopy and optical diffraction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
42. [Canonical wingless signaling regulates cone cell specification in the Drosophila retina](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
43. [Planar polarity and actin dynamics in the epidermis of Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
44. [Wingless effects mesoderm patterning and ectoderm segmentation events via induction of its downstream target sloppy paired](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
45. [Determination of cell fate along the anteroposterior axis of the Drosophila ventral midline.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
46. [Regulation of pattern formation in the Drosophila hindgut by wg, hh, dpp, and en.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
47. [Developmental analysis and squamous morphogenesis of the peripodial epithelium in Drosophila imaginal discs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
48. [A wingless-dependent polar coordinate system in Drosophila imaginal discs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
49. [Different Spatial and Temporal Interactions betweenNotch, wingless,andvestigialSpecify Proximal and Distal Pattern Elements of the Wing inDrosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)
50. [miR-965 controls cell proliferation and migration during tissue morphogenesis in the Drosophila abdomen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09615)