# What makes it difficult to refine protein models further via molecular dynamics simulations?

> Research article (Proteins Structure Function and Bioinformatics, 2017) · cited 41× · AI/ML

**Wikidata**: [openalex:W2763525793](https://www.wikidata.org/wiki/openalex:W2763525793)  
**Source**: https://4ort.xyz/entity/what-makes-it-difficult-to-refine-protein-models-further-via-molecular-dynamics-simulations