# WD repeat domain 77

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21111416](https://www.wikidata.org/wiki/Q21111416)  
**Source**: https://4ort.xyz/entity/wd-repeat-domain-77-q21111416


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9BQA1)
3. Q20641742
4. [5-Hydroxymethylcytosine Plays a Critical Role in Glioblastomagenesis by Recruiting the CHTOP-Methylosome Complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
5. [Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
6. [APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
7. [Dynamic protein-protein interaction wiring of the human spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
8. [Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
9. [MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
10. [Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
11. [Human respiratory syncytial virus N, P and M protein interactions in HEK-293T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
12. [A novel WD repeat protein component of the methylosome binds Sm proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
13. [Crystal structure of the human PRMT5:MEP50 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
14. [Purification and identification of a novel complex which is involved in androgen receptor-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BQA1&geneProductId=UniProtKB:Q9BQA1)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
17. [RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
18. [An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQA1)
19. Ensembl Release 99