# WD repeat domain 5

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21171851](https://www.wikidata.org/wiki/Q21171851)  
**Source**: https://4ort.xyz/entity/wd-repeat-domain-5-q21171851


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P61964)
3. Q20641742
4. [Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
5. [Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
6. [Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
7. [CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
8. [Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
9. [On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
10. [Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
11. [Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
12. [PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
13. [CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
14. [Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
15. [Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
16. [WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kappaB activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
17. [The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
18. [SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
19. [A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
20. [Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
21. [WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
22. [Structural basis for molecular recognition and presentation of histone H3 by WDR5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
23. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
24. [Regulation of transcription by the MLL2 complex and MLL complex–associated AKAP95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
25. [Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
26. [Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
27. [Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
28. [Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
29. [Structural and Biochemical Insights into MLL1 Core Complex Assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
30. [A High-Density Map for Navigating the Human Polycomb Complexome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
31. [Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
32. [Crosstalk between leukemia-associated proteins MOZ and MLL regulates HOX gene expression in human cord blood CD34+ cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
33. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
34. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61964&geneProductId=UniProtKB:P61964)
35. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
36. [Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61964&geneProductId=UniProtKB:P61964)
37. [Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61964&geneProductId=UniProtKB:P61964)
38. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
39. [PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61964&geneProductId=UniProtKB:P61964)
40. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61964&geneProductId=UniProtKB:P61964)
41. [Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
42. [Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61964&geneProductId=UniProtKB:P61964)
43. [On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61964&geneProductId=UniProtKB:P61964)
44. [Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964)
45. Ensembl Release 99