# VPS35 retromer complex component

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21125246](https://www.wikidata.org/wiki/Q21125246)  
**Source**: https://4ort.xyz/entity/vps35-retromer-complex-component


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q96QK1)
3. Q20641742
4. [Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
5. [The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
6. [SNX12 role in endosome membrane transport](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
7. [Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
8. [A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
9. [Endosomal recruitment of the WASH complex: active sequences and mutations impairing interaction with the retromer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
10. [Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
11. [A mechanism for retromer endosomal coat complex assembly with cargo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
12. [Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
13. [GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
14. [Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
15. [Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein Aggregation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
16. [VPS35 regulates cell surface recycling and signaling of dopamine receptor D1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
17. [The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
18. [Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
19. [Pharmacological chaperones stabilize retromer to limit APP processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
20. [The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
21. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
22. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
23. [The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
24. [Functional architecture of the retromer cargo-recognition complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
25. [Cellular cofactors affecting hepatitis C virus infection and replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
26. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
27. [The vacuolar-ATPase inhibitor bafilomycin and mutant VPS35 inhibit canonical Wnt signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
28. [The regulation and deregulation of Wnt signaling by PARK genes in health and disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
29. [Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
30. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
31. [Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
32. [Integral and associated lysosomal membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
33. [Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
34. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
35. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
36. [Retromer: Structure, function, and roles in mammalian disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
37. [Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein Aggregation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
38. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
39. [Integral and associated lysosomal membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
40. [The regulation and deregulation of Wnt signaling by PARK genes in health and disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
41. [The vacuolar-ATPase inhibitor bafilomycin and mutant VPS35 inhibit canonical Wnt signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
42. [Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
43. [Retromer: Structure, function, and roles in mammalian disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
44. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
45. [The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
46. [A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
47. [Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
48. [Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96QK1&geneProductId=UniProtKB:Q96QK1)
49. [Retromer Ensures the Degradation of Autophagic Cargo by Maintaining Lysosome Function in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)
50. [Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synuclein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96QK1)