# Von Hippel-Lindau tumor suppressor

> mammalian protein found in Mus musculus

**Wikidata**: [Q14905477](https://www.wikidata.org/wiki/Q14905477)  
**Source**: https://4ort.xyz/entity/von-hippel-lindau-tumor-suppressor-q14905477


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P40338)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
6. [VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
7. [The von Hippel-Lindau tumour suppressor interacts with microtubules through kinesin-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
8. [Regulation of ubiquitin ligase dynamics by the nucleolus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40338&geneProductId=UniProtKB:P40338)
10. [Regulation of ubiquitin ligase dynamics by the nucleolus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40338&geneProductId=UniProtKB:P40338)
11. [The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
12. [Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
13. [pVHL function is essential for endothelial extracellular matrix deposition.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
14. [Vhlh gene deletion induces Hif-1-mediated cell death in thymocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
15. [von Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-α and VEGF-A upregulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
16. [Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
17. [SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40338)
18. ensembl Release 106