# Voltage dependent anion channel 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21133152](https://www.wikidata.org/wiki/Q21133152)  
**Source**: https://4ort.xyz/entity/voltage-dependent-anion-channel-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P21796)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
5. [Plasminogen kringle 5 induces endothelial cell apoptosis by triggering a voltage-dependent anion channel 1 (VDAC1) positive feedback loop](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21796&geneProductId=UniProtKB:P21796)
7. [Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21796&geneProductId=UniProtKB:P21796)
8. [SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
9. [Human Bop is a novel BH3-only member of the Bcl-2 protein family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
10. [Enzymatically inactive adenylate kinase 4 interacts with mitochondrial ADP/ATP translocase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
11. [Expression of leucine-rich repeat kinase 2 (LRRK2) inhibits the processing of uMtCK to induce cell death in a cell culture model system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
12. [A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
13. [Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
14. [PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
15. [Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
16. [Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
17. [New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
18. [Structure of the human voltage-dependent anion channel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
19. [Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
21. [Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21796&geneProductId=UniProtKB:P21796)
22. [Hepatitis C virus core protein suppresses mitophagy by interacting with parkin in the context of mitochondrial depolarization](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21796&geneProductId=UniProtKB:P21796)
23. [Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21796&geneProductId=UniProtKB:P21796)
24. [The layered structure of human mitochondrial DNA nucleoids](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
25. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21796&geneProductId=UniProtKB:P21796)
26. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21796&geneProductId=UniProtKB:P21796)
27. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21796&geneProductId=UniProtKB:P21796)
28. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21796&geneProductId=UniProtKB:P21796)
29. [Proteomic characterization of the human sperm nucleus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21796&geneProductId=UniProtKB:P21796)
30. [Proteomic characterization of the human sperm nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
31. [Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
32. [Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
33. [Hepatitis C virus core protein suppresses mitophagy by interacting with parkin in the context of mitochondrial depolarization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
34. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
35. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
36. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
37. [Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco‐2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
38. [PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
39. [Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21796)
40. Ensembl Release 99